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Items: 1 to 20 of 263

1.

Variants in the SNCA gene associate with motor progression while variants in the MAPT gene associate with the severity of Parkinson's disease.

Wang G, Huang Y, Chen W, Chen S, Wang Y, Xiao Q, Liu J, Fung VS, Halliday G, Chen S.

Parkinsonism Relat Disord. 2016 Mar;24:89-94. doi: 10.1016/j.parkreldis.2015.12.018. Epub 2015 Dec 30.

PMID:
26776090
2.

SNCA Gene, but Not MAPT, Influences Onset Age of Parkinson's Disease in Chinese and Australians.

Huang Y, Wang G, Rowe D, Wang Y, Kwok JB, Xiao Q, Mastaglia F, Liu J, Chen SD, Halliday G.

Biomed Res Int. 2015;2015:135674. doi: 10.1155/2015/135674. Epub 2015 Apr 15.

3.

Protective effect of LRRK2 p.R1398H on risk of Parkinson's disease is independent of MAPT and SNCA variants.

Heckman MG, Elbaz A, Soto-Ortolaza AI, Serie DJ, Aasly JO, Annesi G, Auburger G, Bacon JA, Boczarska-Jedynak M, Bozi M, Brighina L, Chartier-Harlin MC, Dardiotis E, Destée A, Ferrarese C, Ferraris A, Fiske B, Gispert S, Hadjigeorgiou GM, Hattori N, Ioannidis JP, Jasinska-Myga B, Jeon BS, Kim YJ, Klein C, Kruger R, Kyratzi E, Lin CH, Lohmann K, Loriot MA, Lynch T, Mellick GD, Mutez E, Opala G, Park SS, Petrucci S, Quattrone A, Sharma M, Silburn PA, Sohn YH, Stefanis L, Tadic V, Tomiyama H, Uitti RJ, Valente EM, Vassilatis DK, Vilariño-Güell C, White LR, Wirdefeldt K, Wszolek ZK, Wu RM, Xiromerisiou G, Maraganore DM, Farrer MJ, Ross OA; Genetic Epidemiology Of Parkinson's Disease (GEO-PD) Consortium.

Neurobiol Aging. 2014 Jan;35(1):266.e5-14. doi: 10.1016/j.neurobiolaging.2013.07.013. Epub 2013 Aug 17.

4.

Independent and joint effects of the MAPT and SNCA genes in Parkinson disease.

Elbaz A, Ross OA, Ioannidis JP, Soto-Ortolaza AI, Moisan F, Aasly J, Annesi G, Bozi M, Brighina L, Chartier-Harlin MC, Destée A, Ferrarese C, Ferraris A, Gibson JM, Gispert S, Hadjigeorgiou GM, Jasinska-Myga B, Klein C, Krüger R, Lambert JC, Lohmann K, van de Loo S, Loriot MA, Lynch T, Mellick GD, Mutez E, Nilsson C, Opala G, Puschmann A, Quattrone A, Sharma M, Silburn PA, Stefanis L, Uitti RJ, Valente EM, Vilariño-Güell C, Wirdefeldt K, Wszolek ZK, Xiromerisiou G, Maraganore DM, Farrer MJ; Genetic Epidemiology of Parkinson's Disease (GEO-PD) Consortium.

Ann Neurol. 2011 May;69(5):778-92. doi: 10.1002/ana.22321. Epub 2011 Mar 9.

5.

Does α-synuclein have a dual and opposing effect in preclinical vs. clinical Parkinson's disease?

Markopoulou K, Biernacka JM, Armasu SM, Anderson KJ, Ahlskog JE, Chase BA, Chung SJ, Cunningham JM, Farrer M, Frigerio R, Maraganore DM.

Parkinsonism Relat Disord. 2014 Jun;20(6):584-9; discussion 584. doi: 10.1016/j.parkreldis.2014.02.021. Epub 2014 Mar 5.

6.

SNCA and MAPT genes: Independent and joint effects in Parkinson disease in the Italian population.

Trotta L, Guella I, Soldà G, Sironi F, Tesei S, Canesi M, Pezzoli G, Goldwurm S, Duga S, Asselta R.

Parkinsonism Relat Disord. 2012 Mar;18(3):257-62. doi: 10.1016/j.parkreldis.2011.10.014. Epub 2011 Nov 21.

7.

APOE, MAPT, and SNCA genes and cognitive performance in Parkinson disease.

Mata IF, Leverenz JB, Weintraub D, Trojanowski JQ, Hurtig HI, Van Deerlin VM, Ritz B, Rausch R, Rhodes SL, Factor SA, Wood-Siverio C, Quinn JF, Chung KA, Peterson AL, Espay AJ, Revilla FJ, Devoto J, Hu SC, Cholerton BA, Wan JY, Montine TJ, Edwards KL, Zabetian CP.

JAMA Neurol. 2014 Nov;71(11):1405-12. doi: 10.1001/jamaneurol.2014.1455.

8.

SNCA, MAPT, and GSK3B in Parkinson disease: a gene-gene interaction study.

Wider C, Vilariño-Güell C, Heckman MG, Jasinska-Myga B, Ortolaza-Soto AI, Diehl NN, Crook JE, Cobb SA, Bacon JA, Aasly JO, Gibson JM, Lynch T, Uitti RJ, Wszolek ZK, Farrer MJ, Ross OA.

Eur J Neurol. 2011 Jun;18(6):876-81. doi: 10.1111/j.1468-1331.2010.03297.x. Epub 2010 Dec 15.

PMID:
21159074
9.

Variants in GBA, SNCA, and MAPT influence Parkinson disease risk, age at onset, and progression.

Davis AA, Andruska KM, Benitez BA, Racette BA, Perlmutter JS, Cruchaga C.

Neurobiol Aging. 2016 Jan;37:209.e1-209.e7. doi: 10.1016/j.neurobiolaging.2015.09.014. Epub 2015 Sep 30.

10.

Do interactions between SNCA, MAPT, and LRRK2 genes contribute to Parkinson's disease susceptibility?

Biernacka JM, Armasu SM, Cunningham JM, Ahlskog JE, Chung SJ, Maraganore DM.

Parkinsonism Relat Disord. 2011 Dec;17(10):730-6. doi: 10.1016/j.parkreldis.2011.07.001. Epub 2011 Aug 3.

11.

α-Synuclein genetic variants predict faster motor symptom progression in idiopathic Parkinson disease.

Ritz B, Rhodes SL, Bordelon Y, Bronstein J.

PLoS One. 2012;7(5):e36199. doi: 10.1371/journal.pone.0036199. Epub 2012 May 15.

12.

Hyposmia correlates with SNCA variant and non-motor symptoms in Chinese patients with Parkinson's disease.

Chen W, Kang WY, Chen S, Wang Y, Xiao Q, Wang G, Liu J, Chen SD.

Parkinsonism Relat Disord. 2015 Jun;21(6):610-4. doi: 10.1016/j.parkreldis.2015.03.021. Epub 2015 Mar 31.

PMID:
25921825
13.

Genetic Variants of SNCA Are Associated with Susceptibility to Parkinson's Disease but Not Amyotrophic Lateral Sclerosis or Multiple System Atrophy in a Chinese Population.

Chen Y, Wei QQ, Ou R, Cao B, Chen X, Zhao B, Guo X, Yang Y, Chen K, Wu Y, Song W, Shang HF.

PLoS One. 2015 Jul 24;10(7):e0133776. doi: 10.1371/journal.pone.0133776. eCollection 2015.

14.

Replication of MAPT and SNCA, but not PARK16-18, as susceptibility genes for Parkinson's disease.

Mata IF, Yearout D, Alvarez V, Coto E, de Mena L, Ribacoba R, Lorenzo-Betancor O, Samaranch L, Pastor P, Cervantes S, Infante J, Garcia-Gorostiaga I, Sierra M, Combarros O, Snapinn KW, Edwards KL, Zabetian CP.

Mov Disord. 2011 Apr;26(5):819-23. doi: 10.1002/mds.23642. Epub 2011 Mar 21.

15.

Common variants in PARK loci and related genes and Parkinson's disease.

Chung SJ, Armasu SM, Biernacka JM, Lesnick TG, Rider DN, Lincoln SJ, Ortolaza AI, Farrer MJ, Cunningham JM, Rocca WA, Maraganore DM.

Mov Disord. 2011 Feb 1;26(2):280-8. doi: 10.1002/mds.23376. Epub 2010 Dec 13.

16.

Interaction between α-synuclein and tau genotypes and the progression of Parkinson's disease.

Huang Y, Rowe DB, Halliday GM.

J Parkinsons Dis. 2011;1(3):271-6. doi: 10.3233/JPD-2011-11027.

PMID:
23939307
17.

Tau and alpha-synuclein in susceptibility to, and dementia in, Parkinson's disease.

Goris A, Williams-Gray CH, Clark GR, Foltynie T, Lewis SJ, Brown J, Ban M, Spillantini MG, Compston A, Burn DJ, Chinnery PF, Barker RA, Sawcer SJ.

Ann Neurol. 2007 Aug;62(2):145-53.

PMID:
17683088
18.

Polygenic determinants of Parkinson's disease in a Chinese population.

Guo JF, Li K, Yu RL, Sun QY, Wang L, Yao LY, Hu YC, Lv ZY, Luo LZ, Shen L, Jiang H, Yan XX, Pan Q, Xia K, Tang BS.

Neurobiol Aging. 2015 Apr;36(4):1765.e1-1765.e6. doi: 10.1016/j.neurobiolaging.2014.12.030. Epub 2015 Jan 6.

PMID:
25623333
19.

Genetic susceptibility loci, environmental exposures, and Parkinson's disease: a case-control study of gene-environment interactions.

Chung SJ, Armasu SM, Anderson KJ, Biernacka JM, Lesnick TG, Rider DN, Cunningham JM, Ahlskog JE, Frigerio R, Maraganore DM.

Parkinsonism Relat Disord. 2013 Jun;19(6):595-9. doi: 10.1016/j.parkreldis.2013.02.008. Epub 2013 Mar 16.

20.

Risk variants of the α-synuclein locus and REM sleep behavior disorder in Parkinson's disease: a genetic association study.

Bjørnarå KA, Pihlstrøm L, Dietrichs E, Toft M.

BMC Neurol. 2018 Feb 21;18(1):20. doi: 10.1186/s12883-018-1023-6.

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