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Items: 1 to 20 of 250

1.

The Hepatitis C Virus-induced NLRP3 Inflammasome Activates the Sterol Regulatory Element-binding Protein (SREBP) and Regulates Lipid Metabolism.

McRae S, Iqbal J, Sarkar-Dutta M, Lane S, Nagaraj A, Ali N, Waris G.

J Biol Chem. 2016 Feb 12;291(7):3254-67. doi: 10.1074/jbc.M115.694059. Epub 2015 Dec 23. Retraction in: J Biol Chem. 2018 Dec 28;293(52):20011.

2.

Activation of sterol regulatory element binding protein and NLRP3 inflammasome in atherosclerotic lesion development in diabetic pigs.

Li Y, Xu S, Jiang B, Cohen RA, Zang M.

PLoS One. 2013 Jun 25;8(6):e67532. doi: 10.1371/journal.pone.0067532. Print 2013.

3.

Human subtilase SKI-1/S1P is a master regulator of the HCV Lifecycle and a potential host cell target for developing indirect-acting antiviral agents.

Olmstead AD, Knecht W, Lazarov I, Dixit SB, Jean F.

PLoS Pathog. 2012 Jan;8(1):e1002468. doi: 10.1371/journal.ppat.1002468. Epub 2012 Jan 5.

4.

Hepatitis C virus activates interleukin-1β via caspase-1-inflammasome complex.

Burdette D, Haskett A, Presser L, McRae S, Iqbal J, Waris G.

J Gen Virol. 2012 Feb;93(Pt 2):235-46. doi: 10.1099/vir.0.034033-0. Epub 2011 Oct 12.

5.

Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages.

Guo C, Chi Z, Jiang D, Xu T, Yu W, Wang Z, Chen S, Zhang L, Liu Q, Guo X, Zhang X, Li W, Lu L, Wu Y, Song BL, Wang D.

Immunity. 2018 Nov 20;49(5):842-856.e7. doi: 10.1016/j.immuni.2018.08.021. Epub 2018 Oct 23.

PMID:
30366764
6.

Reactive oxygen species-induced TXNIP drives fructose-mediated hepatic inflammation and lipid accumulation through NLRP3 inflammasome activation.

Zhang X, Zhang JH, Chen XY, Hu QH, Wang MX, Jin R, Zhang QY, Wang W, Wang R, Kang LL, Li JS, Li M, Pan Y, Huang JJ, Kong LD.

Antioxid Redox Signal. 2015 Apr 1;22(10):848-70. doi: 10.1089/ars.2014.5868.

7.

COPI-mediated retrieval of SCAP is crucial for regulating lipogenesis under basal and sterol-deficient conditions.

Takashima K, Saitoh A, Funabashi T, Hirose S, Yagi C, Nozaki S, Sato R, Shin HW, Nakayama K.

J Cell Sci. 2015 Aug 1;128(15):2805-15. doi: 10.1242/jcs.164137. Epub 2015 Jun 19.

8.

Hepatitis C virus nonstructural 4B protein modulates sterol regulatory element-binding protein signaling via the AKT pathway.

Park CY, Jun HJ, Wakita T, Cheong JH, Hwang SB.

J Biol Chem. 2009 Apr 3;284(14):9237-46. doi: 10.1074/jbc.M808773200. Epub 2009 Feb 9.

9.

EV71 3D Protein Binds with NLRP3 and Enhances the Assembly of Inflammasome Complex.

Wang W, Xiao F, Wan P, Pan P, Zhang Y, Liu F, Wu K, Liu Y, Wu J.

PLoS Pathog. 2017 Jan 6;13(1):e1006123. doi: 10.1371/journal.ppat.1006123. eCollection 2017 Jan. Erratum in: PLoS Pathog. 2018 Mar 12;14 (3):e1006921.

10.

Magnesium isoglycyrrhizinate blocks fructose-induced hepatic NF-κB/NLRP3 inflammasome activation and lipid metabolism disorder.

Zhao XJ, Yang YZ, Zheng YJ, Wang SC, Gu HM, Pan Y, Wang SJ, Xu HJ, Kong LD.

Eur J Pharmacol. 2017 Aug 15;809:141-150. doi: 10.1016/j.ejphar.2017.05.032. Epub 2017 May 17.

PMID:
28526339
11.
12.

Hepatitis C virus stimulates low-density lipoprotein receptor expression to facilitate viral propagation.

Syed GH, Tang H, Khan M, Hassanein T, Liu J, Siddiqui A.

J Virol. 2014 Mar;88(5):2519-29. doi: 10.1128/JVI.02727-13. Epub 2013 Dec 18.

13.

IL-1β production through the NLRP3 inflammasome by hepatic macrophages links hepatitis C virus infection with liver inflammation and disease.

Negash AA, Ramos HJ, Crochet N, Lau DT, Doehle B, Papic N, Delker DA, Jo J, Bertoletti A, Hagedorn CH, Gale M Jr.

PLoS Pathog. 2013;9(4):e1003330. doi: 10.1371/journal.ppat.1003330. Epub 2013 Apr 25.

14.

Mycobacterium abscessus activates the NLRP3 inflammasome via Dectin-1-Syk and p62/SQSTM1.

Lee HM, Yuk JM, Kim KH, Jang J, Kang G, Park JB, Son JW, Jo EK.

Immunol Cell Biol. 2012 Jul;90(6):601-10. doi: 10.1038/icb.2011.72. Epub 2011 Aug 30.

15.

The inflammasome in alcoholic hepatitis: Its relationship with Mallory-Denk body formation.

Peng Y, French BA, Tillman B, Morgan TR, French SW.

Exp Mol Pathol. 2014 Oct;97(2):305-13. doi: 10.1016/j.yexmp.2014.08.006. Epub 2014 Aug 19.

16.

Caspase-1 autoproteolysis is differentially required for NLRP1b and NLRP3 inflammasome function.

Guey B, Bodnar M, Manié SN, Tardivel A, Petrilli V.

Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17254-9. doi: 10.1073/pnas.1415756111. Epub 2014 Nov 17.

17.

Glutamine stimulates the gene expression and processing of sterol regulatory element binding proteins, thereby increasing the expression of their target genes.

Inoue J, Ito Y, Shimada S, Satoh SI, Sasaki T, Hashidume T, Kamoshida Y, Shimizu M, Sato R.

FEBS J. 2011 Aug;278(15):2739-50. doi: 10.1111/j.1742-4658.2011.08204.x. Epub 2011 Jun 22.

18.

Chlamydia pneumoniae harness host NLRP3 inflammasome-mediated caspase-1 activation for optimal intracellular growth in murine macrophages.

Itoh R, Murakami I, Chou B, Ishii K, Soejima T, Suzuki T, Hiromatsu K.

Biochem Biophys Res Commun. 2014 Sep 26;452(3):689-94. doi: 10.1016/j.bbrc.2014.08.128. Epub 2014 Sep 1.

PMID:
25193701
19.

Hepatitis C Virus Infection of Cultured Human Hepatoma Cells Causes Apoptosis and Pyroptosis in Both Infected and Bystander Cells.

Kofahi HM, Taylor NG, Hirasawa K, Grant MD, Russell RS.

Sci Rep. 2016 Dec 15;6:37433. doi: 10.1038/srep37433.

20.

The purinergic 2X7 receptor participates in renal inflammation and injury induced by high-fat diet: possible role of NLRP3 inflammasome activation.

Solini A, Menini S, Rossi C, Ricci C, Santini E, Blasetti Fantauzzi C, Iacobini C, Pugliese G.

J Pathol. 2013 Nov;231(3):342-53. doi: 10.1002/path.4237. Epub 2013 Sep 3.

PMID:
23843215

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