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Plasma fractalkine is a sustained marker of disease severity and outcome in sepsis patients.

Hoogendijk AJ, Wiewel MA, van Vught LA, Scicluna BP, Belkasim-Bohoudi H, Horn J, Zwinderman AH, Klein Klouwenberg PM, Cremer OL, Bonten MJ, Schultz MJ, van der Poll T; MARS consortium.

Crit Care. 2015 Nov 25;19:412. doi: 10.1186/s13054-015-1125-0.


Association of diabetes and diabetes treatment with the host response in critically ill sepsis patients.

van Vught LA, Scicluna BP, Hoogendijk AJ, Wiewel MA, Klein Klouwenberg PM, Cremer OL, Horn J, Nürnberg P, Bonten MM, Schultz MJ, van der Poll T.

Crit Care. 2016 Aug 6;20(1):252. doi: 10.1186/s13054-016-1429-8.


Prognostic value of circulating amino-terminal pro-C-type natriuretic peptide in critically ill patients.

Koch A, Voigt S, Sanson E, Dückers H, Horn A, Zimmermann HW, Trautwein C, Tacke F.

Crit Care. 2011;15(1):R45. doi: 10.1186/cc10007. Epub 2011 Jan 31.


Incidence, Risk Factors, and Attributable Mortality of Secondary Infections in the Intensive Care Unit After Admission for Sepsis.

van Vught LA, Klein Klouwenberg PM, Spitoni C, Scicluna BP, Wiewel MA, Horn J, Schultz MJ, Nürnberg P, Bonten MJ, Cremer OL, van der Poll T; MARS Consortium.

JAMA. 2016 Apr 12;315(14):1469-79. doi: 10.1001/jama.2016.2691.


Circulating soluble urokinase plasminogen activator receptor is stably elevated during the first week of treatment in the intensive care unit and predicts mortality in critically ill patients.

Koch A, Voigt S, Kruschinski C, Sanson E, Dückers H, Horn A, Yagmur E, Zimmermann H, Trautwein C, Tacke F.

Crit Care. 2011;15(1):R63. doi: 10.1186/cc10037. Epub 2011 Feb 16.


Antithrombin levels, morbidity, and mortality in a surgical intensive care unit.

Sakr Y, Reinhart K, Hagel S, Kientopf M, Brunkhorst F.

Anesth Analg. 2007 Sep;105(3):715-23.


Elevated plasma levels of heparin-binding protein in intensive care unit patients with severe sepsis and septic shock.

Linder A, Åkesson P, Inghammar M, Treutiger CJ, Linnér A, Sundén-Cullberg J.

Crit Care. 2012 May 21;16(3):R90. doi: 10.1186/cc11353.


Efficacy and significance of various scores for pneumonia severity in the management of patients with community-acquired pneumonia in China.

Yang Y, Xu F, Shi LY, Diao R, Cheng YS, Chen XY, Jing JY, Wang XD, Shen HH.

Chin Med J (Engl). 2012 Feb;125(4):639-45.


The Host Response in Patients with Sepsis Developing Intensive Care Unit-acquired Secondary Infections.

van Vught LA, Wiewel MA, Hoogendijk AJ, Frencken JF, Scicluna BP, Klein Klouwenberg PMC, Zwinderman AH, Lutter R, Horn J, Schultz MJ, Bonten MMJ, Cremer OL, van der Poll T.

Am J Respir Crit Care Med. 2017 Aug 15;196(4):458-470. doi: 10.1164/rccm.201606-1225OC.


Elevated biomarkers of endothelial dysfunction/activation at ICU admission are associated with sepsis development.

Vassiliou AG, Mastora Z, Orfanos SE, Jahaj E, Maniatis NA, Koutsoukou A, Armaganidis A, Kotanidou A.

Cytokine. 2014 Oct;69(2):240-7. doi: 10.1016/j.cyto.2014.06.010. Epub 2014 Jul 12.


Fractalkine (CX3CL1): a biomarker reflecting symptomatic severity in patients with knee osteoarthritis.

Huo LW, Ye YL, Wang GW, Ye YG.

J Investig Med. 2015 Apr;63(4):626-31. doi: 10.1097/JIM.0000000000000158.


Endocan is useful biomarker of survival and severity in sepsis.

Mihajlovic DM, Lendak DF, Brkic SV, Draskovic BG, Mitic GP, Novakov Mikic AS, Cebovic TN.

Microvasc Res. 2014 May;93:92-7. doi: 10.1016/j.mvr.2014.04.004. Epub 2014 Apr 21.


Incidence, risk factors, and outcome of severe sepsis and septic shock in adults. A multicenter prospective study in intensive care units. French ICU Group for Severe Sepsis.

Brun-Buisson C, Doyon F, Carlet J, Dellamonica P, Gouin F, Lepoutre A, Mercier JC, Offenstadt G, Régnier B.

JAMA. 1995 Sep 27;274(12):968-74.


Lipopolysaccharide binding protein in a surgical intensive care unit: a marker of sepsis?

Sakr Y, Burgett U, Nacul FE, Reinhart K, Brunkhorst F.

Crit Care Med. 2008 Jul;36(7):2014-22. doi: 10.1097/CCM.0b013e31817b86e3.


A combination of early warning score and lactate to predict intensive care unit transfer of inpatients with severe sepsis/septic shock.

Yoo JW, Lee JR, Jung YK, Choi SH, Son JS, Kang BJ, Park TS, Huh JW, Lim CM, Koh Y, Hong SB.

Korean J Intern Med. 2015 Jul;30(4):471-7. doi: 10.3904/kjim.2015.30.4.471. Epub 2015 Jun 29.


Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis.

Ricciuto DR, dos Santos CC, Hawkes M, Toltl LJ, Conroy AL, Rajwans N, Lafferty EI, Cook DJ, Fox-Robichaud A, Kahnamoui K, Kain KC, Liaw PC, Liles WC.

Crit Care Med. 2011 Apr;39(4):702-10. doi: 10.1097/CCM.0b013e318206d285.


[Changes in plasma adiponectin concentrations in sepsis and its correlation with the severity of the disease].

Gong XY, Zhang XL, Zang B.

Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2012 Sep;24(9):541-5. Chinese.


Revisiting the white blood cell count: immature granulocytes count as a diagnostic marker to discriminate between SIRS and sepsis--a prospective, observational study.

Nierhaus A, Klatte S, Linssen J, Eismann NM, Wichmann D, Hedke J, Braune SA, Kluge S.

BMC Immunol. 2013 Feb 12;14:8. doi: 10.1186/1471-2172-14-8.


[Epidemiology of infection and sepsis in intensive care unit patients].

Le Gall JR, Alberti C, Brun Buisson C.

Bull Acad Natl Med. 2004;188(7):1115-25; discussion 1125-6. French.


Time course of angiopoietin-2 release during experimental human endotoxemia and sepsis.

Kümpers P, van Meurs M, David S, Molema G, Bijzet J, Lukasz A, Biertz F, Haller H, Zijlstra JG.

Crit Care. 2009;13(3):R64. doi: 10.1186/cc7866. Epub 2009 May 5.

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