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Items: 1 to 20 of 80

1.

MYC-induced reprogramming of glutamine catabolism supports optimal virus replication.

Thai M, Thaker SK, Feng J, Du Y, Hu H, Ting Wu T, Graeber TG, Braas D, Christofk HR.

Nat Commun. 2015 Nov 12;6:8873. doi: 10.1038/ncomms9873.

2.

Adenovirus E4ORF1-induced MYC activation promotes host cell anabolic glucose metabolism and virus replication.

Thai M, Graham NA, Braas D, Nehil M, Komisopoulou E, Kurdistani SK, McCormick F, Graeber TG, Christofk HR.

Cell Metab. 2014 Apr 1;19(4):694-701. doi: 10.1016/j.cmet.2014.03.009.

3.

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction.

Wise DR, DeBerardinis RJ, Mancuso A, Sayed N, Zhang XY, Pfeiffer HK, Nissim I, Daikhin E, Yudkoff M, McMahon SB, Thompson CB.

Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18782-7. doi: 10.1073/pnas.0810199105. Epub 2008 Nov 24.

4.

Myc promotes glutaminolysis in human neuroblastoma through direct activation of glutaminase 2.

Xiao D, Ren P, Su H, Yue M, Xiu R, Hu Y, Liu H, Qing G.

Oncotarget. 2015 Dec 1;6(38):40655-66. doi: 10.18632/oncotarget.5821.

5.

Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction.

Fogal V, Babic I, Chao Y, Pastorino S, Mukthavaram R, Jiang P, Cho YJ, Pingle SC, Crawford JR, Piccioni DE, Kesari S.

Oncotarget. 2015 Jan 20;6(2):1157-70.

6.

Cross-talk between ER and HER2 regulates c-MYC-mediated glutamine metabolism in aromatase inhibitor resistant breast cancer cells.

Chen Z, Wang Y, Warden C, Chen S.

J Steroid Biochem Mol Biol. 2015 May;149:118-27. doi: 10.1016/j.jsbmb.2015.02.004. Epub 2015 Feb 12.

7.

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation.

Wang R, Dillon CP, Shi LZ, Milasta S, Carter R, Finkelstein D, McCormick LL, Fitzgerald P, Chi H, Munger J, Green DR.

Immunity. 2011 Dec 23;35(6):871-82. doi: 10.1016/j.immuni.2011.09.021.

8.

The mTORC1/S6K1 pathway regulates glutamine metabolism through the eIF4B-dependent control of c-Myc translation.

Csibi A, Lee G, Yoon SO, Tong H, Ilter D, Elia I, Fendt SM, Roberts TM, Blenis J.

Curr Biol. 2014 Oct 6;24(19):2274-80. doi: 10.1016/j.cub.2014.08.007. Epub 2014 Sep 11.

9.

Oncogenic Myc Induces Expression of Glutamine Synthetase through Promoter Demethylation.

Bott AJ, Peng IC, Fan Y, Faubert B, Zhao L, Li J, Neidler S, Sun Y, Jaber N, Krokowski D, Lu W, Pan JA, Powers S, Rabinowitz J, Hatzoglou M, Murphy DJ, Jones R, Wu S, Girnun G, Zong WX.

Cell Metab. 2015 Dec 1;22(6):1068-77. doi: 10.1016/j.cmet.2015.09.025. Epub 2015 Oct 23.

10.

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism.

Gao P, Tchernyshyov I, Chang TC, Lee YS, Kita K, Ochi T, Zeller KI, De Marzo AM, Van Eyk JE, Mendell JT, Dang CV.

Nature. 2009 Apr 9;458(7239):762-5. doi: 10.1038/nature07823. Epub 2009 Feb 15.

11.

Metabolism goes viral.

Miyake-Stoner SJ, O'Shea CC.

Cell Metab. 2014 Apr 1;19(4):549-50. doi: 10.1016/j.cmet.2014.03.022.

12.

MYC, microRNAs and glutamine addiction in cancers.

Dang CV.

Cell Cycle. 2009 Oct 15;8(20):3243-5. Epub 2009 Oct 15.

PMID:
19806017
13.

Adenoviral E1A function through Myc.

Chakraborty AA, Tansey WP.

Cancer Res. 2009 Jan 1;69(1):6-9. doi: 10.1158/0008-5472.CAN-08-3026. Review.

14.

The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type.

Yuneva MO, Fan TW, Allen TD, Higashi RM, Ferraris DV, Tsukamoto T, Matés JM, Alonso FJ, Wang C, Seo Y, Chen X, Bishop JM.

Cell Metab. 2012 Feb 8;15(2):157-70. doi: 10.1016/j.cmet.2011.12.015.

15.

A Time for MYC: Metabolism and Therapy.

Dang CV.

Cold Spring Harb Symp Quant Biol. 2016;81:79-83. doi: 10.1101/sqb.2016.81.031153. Epub 2017 Feb 7. Review.

PMID:
28174256
16.

Rethinking the Warburg effect with Myc micromanaging glutamine metabolism.

Dang CV.

Cancer Res. 2010 Feb 1;70(3):859-62. doi: 10.1158/0008-5472.CAN-09-3556. Epub 2010 Jan 19. Review.

17.

Adenovirus E4-ORF1 Dysregulates Epidermal Growth Factor and Insulin/Insulin-Like Growth Factor Receptors To Mediate Constitutive Myc Expression.

Kong K, Kumar M, Taruishi M, Javier RT.

J Virol. 2015 Nov;89(21):10774-85. doi: 10.1128/JVI.01463-15. Epub 2015 Aug 12.

18.

Mutual interference of adenovirus infection and myc expression.

Löhr K, Hartmann O, Schäfer H, Dobbelstein M.

J Virol. 2003 Jul;77(14):7936-44.

19.

Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling.

Yang C, Sudderth J, Dang T, Bachoo RM, McDonald JG, DeBerardinis RJ.

Cancer Res. 2009 Oct 15;69(20):7986-93. doi: 10.1158/0008-5472.CAN-09-2266. Epub 2009 Oct 13. Erratum in: Cancer Res. 2010 Feb 1;70(3):1275. Bachoo, Robert G [corrected to Bachoo, Robert M].

20.

Targeting Glutamine Induces Apoptosis: A Cancer Therapy Approach.

Chen L, Cui H.

Int J Mol Sci. 2015 Sep 22;16(9):22830-55. doi: 10.3390/ijms160922830. Review.

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