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Items: 1 to 20 of 74

1.

Degradation of host ubiquitin E3 ligase Itch by human cytomegalovirus UL42.

Koshizuka T, Tanaka K, Suzutani T.

J Gen Virol. 2016 Jan;97(1):196-208. doi: 10.1099/jgv.0.000336. Epub 2015 Nov 9.

PMID:
26555021
2.

Herpes simplex virus UL56 interacts with and regulates the Nedd4-family ubiquitin ligase Itch.

Ushijima Y, Luo C, Kamakura M, Goshima F, Kimura H, Nishiyama Y.

Virol J. 2010 Aug 3;7:179. doi: 10.1186/1743-422X-7-179.

3.

Herpesviruses possess conserved proteins for interaction with Nedd4 family ubiquitin E3 ligases.

Koshizuka T, Kobayashi T, Ishioka K, Suzutani T.

Sci Rep. 2018 Mar 13;8(1):4447. doi: 10.1038/s41598-018-22682-2.

4.

Herpes simplex virus type 2 UL56 interacts with the ubiquitin ligase Nedd4 and increases its ubiquitination.

Ushijima Y, Koshizuka T, Goshima F, Kimura H, Nishiyama Y.

J Virol. 2008 Jun;82(11):5220-33. doi: 10.1128/JVI.02515-07. Epub 2008 Mar 19.

5.

Regulation of Itch and Nedd4 E3 Ligase Activity and Degradation by LRAD3.

Noyes NC, Hampton B, Migliorini M, Strickland DK.

Biochemistry. 2016 Mar 1;55(8):1204-13. doi: 10.1021/acs.biochem.5b01218. Epub 2016 Feb 17.

PMID:
26854353
6.

Transmembrane Protein pUL50 of Human Cytomegalovirus Inhibits ISGylation by Downregulating UBE1L.

Lee MK, Kim YJ, Kim YE, Han TH, Milbradt J, Marschall M, Ahn JH.

J Virol. 2018 Jul 17;92(15). pii: e00462-18. doi: 10.1128/JVI.00462-18. Print 2018 Aug 1.

PMID:
29743376
7.

ITCH E3 Ubiquitin Ligase Interacts with Ebola Virus VP40 To Regulate Budding.

Han Z, Sagum CA, Bedford MT, Sidhu SS, Sudol M, Harty RN.

J Virol. 2016 Sep 29;90(20):9163-71. doi: 10.1128/JVI.01078-16. Print 2016 Oct 15.

8.

Itch WW Domains Inhibit Its E3 Ubiquitin Ligase Activity by Blocking E2-E3 Ligase Trans-thiolation.

Riling C, Kamadurai H, Kumar S, O'Leary CE, Wu KP, Manion EE, Ying M, Schulman BA, Oliver PM.

J Biol Chem. 2015 Sep 25;290(39):23875-87. doi: 10.1074/jbc.M115.649269. Epub 2015 Aug 5.

9.

Herpes simplex virus type 2 tegument protein UL56 relocalizes ubiquitin ligase Nedd4 and has a role in transport and/or release of virions.

Ushijima Y, Goshima F, Kimura H, Nishiyama Y.

Virol J. 2009 Oct 16;6:168. doi: 10.1186/1743-422X-6-168.

10.

The E3 ubiquitin ligase Itch and Yap1 have antagonistic roles in the regulation of ASPP2 protein stability.

Gao K, An J, Zhang Y, Jin X, Ma J, Peng J, Tang Y, Yu L, Zhang P, Wang C.

FEBS Lett. 2015 Jan 2;589(1):94-101. doi: 10.1016/j.febslet.2014.11.030. Epub 2014 Nov 29.

11.

The E3 ubiquitin ligase Itch regulates sorting nexin 9 through an unconventional substrate recognition domain.

Baumann C, Lindholm CK, Rimoldi D, Lévy F.

FEBS J. 2010 Jul;277(13):2803-14. doi: 10.1111/j.1742-4658.2010.07698.x. Epub 2010 May 20.

12.

Human cytomegalovirus IE1 downregulates Hes1 in neural progenitor cells as a potential E3 ubiquitin ligase.

Liu XJ, Yang B, Huang SN, Wu CC, Li XJ, Cheng S, Jiang X, Hu F, Ming YZ, Nevels M, Britt WJ, Rayner S, Tang Q, Zeng WB, Zhao F, Luo MH.

PLoS Pathog. 2017 Jul 27;13(7):e1006542. doi: 10.1371/journal.ppat.1006542. eCollection 2017 Jul.

13.

The Ubiquitin Ligase Itch and Ubiquitination Regulate BFRF1-Mediated Nuclear Envelope Modification for Epstein-Barr Virus Maturation.

Lee CP, Liu GT, Kung HN, Liu PT, Liao YT, Chow LP, Chang LS, Chang YH, Chang CW, Shu WC, Angers A, Farina A, Lin SF, Tsai CH, Bouamr F, Chen MR.

J Virol. 2016 Sep 29;90(20):8994-9007. doi: 10.1128/JVI.01235-16. Print 2016 Oct 15.

14.

The E3 ubiquitin ligase Itch regulates tumor suppressor protein RASSF5/NORE1 stability in an acetylation-dependent manner.

Suryaraja R, Anitha M, Anbarasu K, Kumari G, Mahalingam S.

Cell Death Dis. 2013 Mar 28;4:e565. doi: 10.1038/cddis.2013.91.

16.

Proteasome-dependent disruption of the E3 ubiquitin ligase anaphase-promoting complex by HCMV protein pUL21a.

Fehr AR, Gualberto NC, Savaryn JP, Terhune SS, Yu D.

PLoS Pathog. 2012;8(7):e1002789. doi: 10.1371/journal.ppat.1002789. Epub 2012 Jul 5.

17.

The E3 ligase Aip4/Itch ubiquitinates and targets ErbB-4 for degradation.

Omerovic J, Santangelo L, Puggioni EM, Marrocco J, Dall'Armi C, Palumbo C, Belleudi F, Di Marcotullio L, Frati L, Torrisi MR, Cesareni G, Gulino A, Alimandi M.

FASEB J. 2007 Sep;21(11):2849-62. Epub 2007 Apr 26.

PMID:
17463226
18.

The E3 ubiquitin ligase ITCH negatively regulates canonical Wnt signaling by targeting dishevelled protein.

Wei W, Li M, Wang J, Nie F, Li L.

Mol Cell Biol. 2012 Oct;32(19):3903-12. doi: 10.1128/MCB.00251-12. Epub 2012 Jul 23.

19.

SIMPLE/LITAF expression induces the translocation of the ubiquitin ligase itch towards the lysosomal compartments.

Eaton HE, Desrochers G, Drory SB, Metcalf J, Angers A, Brunetti CR.

PLoS One. 2011 Feb 4;6(2):e16873. doi: 10.1371/journal.pone.0016873.

20.

The HECT domain ligase itch ubiquitinates endophilin and localizes to the trans-Golgi network and endosomal system.

Angers A, Ramjaun AR, McPherson PS.

J Biol Chem. 2004 Mar 19;279(12):11471-9. Epub 2003 Dec 18.

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