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Items: 1 to 20 of 42

1.

Csf2 and Ptgs2 Epigenetic Dysregulation in Diabetes-prone Bicongenic B6.NODC11bxC1tb Mice.

Garrigan E, Belkin NS, Seydel F, Han Z, Carter J, McDuffie M, Morel L, Peck AB, Clare-Salzler MJ, Atkinson M, Wasserfall C, Davoodi-Semiromi A, Shi JD, Haskell-Luevano C, Yang LJ, Alexander JJ, Cdebaca A, Piliant T, Riggs C, Amick M, Litherland SA.

Genet Epigenet. 2015 Oct 11;7:5-17. doi: 10.4137/GEG.S29696. eCollection 2015.

2.

Persistent STAT5 phosphorylation and epigenetic dysregulation of GM-CSF and PGS2/COX2 expression in Type 1 diabetic human monocytes.

Garrigan E, Belkin NS, Alexander JJ, Han Z, Seydel F, Carter J, Atkinson M, Wasserfall C, Clare-Salzler MJ, Amick MA, Litherland SA.

PLoS One. 2013 Oct 18;8(10):e76919. doi: 10.1371/journal.pone.0076919. eCollection 2013.

3.

GM-CSF induces STAT5 binding at epigenetic regulatory sites within the Csf2 promoter of non-obese diabetic (NOD) mouse myeloid cells.

Seydel F, Garrigan E, Stutevoss B, Belkin N, Makadia B, Carter J, Shi JD, Davoodi-Semiromi A, McDuffie M, Litherland SA.

J Autoimmun. 2008 Dec;31(4):377-84. doi: 10.1016/j.jaut.2008.08.010. Epub 2008 Oct 21.

4.
5.

NOD x 129.H2(g7) backcross delineates 129S1/SvImJ-derived genomic regions modulating type 1 diabetes development in mice.

Leiter EH, Reifsnyder PC, Wallace R, Li R, King B, Churchill GC.

Diabetes. 2009 Jul;58(7):1700-3. doi: 10.2337/db09-0120. Epub 2009 Mar 31.

6.

Increased autoimmune diabetes in pIgR-deficient NOD mice is due to a "Hitchhiking" interval that refines the genetic effect of Idd5.4.

Simpfendorfer KR, Strugnell RA, Brodnicki TC, Wijburg OL.

PLoS One. 2015 Apr 2;10(4):e0121979. doi: 10.1371/journal.pone.0121979. eCollection 2015.

7.

Characterization of PAF-AH Ib1 in NOD mice: PAF-AH may not be a candidate gene of the diabetes susceptibility Idd4.1 locus.

Mi QS, Zhou L, Grattan M, Wang ZZ, Sivilotti M, She JX, Delovitch TL.

Ann N Y Acad Sci. 2006 Oct;1079:147-52.

PMID:
17130546
8.

Identification of the inflammasome Nlrp1b as the candidate gene conferring diabetes risk at the Idd4.1 locus in the nonobese diabetic mouse.

Motta VN, Markle JG, Gulban O, Mortin-Toth S, Liao KC, Mogridge J, Steward CA, Danska JS.

J Immunol. 2015 Jun 15;194(12):5663-73. doi: 10.4049/jimmunol.1400913. Epub 2015 May 11.

9.

Distinct genetic control of autoimmune neuropathy and diabetes in the non-obese diabetic background.

Bour-Jordan H, Thompson HL, Giampaolo JR, Davini D, Rosenthal W, Bluestone JA.

J Autoimmun. 2013 Sep;45:58-67. doi: 10.1016/j.jaut.2013.06.005. Epub 2013 Jul 12.

10.

The idd4 locus displays sex-specific epistatic effects on type 1 diabetes susceptibility in nonobese diabetic mice.

Ivakine EA, Mortin-Toth SM, Gulban OM, Valova A, Canty A, Scott C, Danska JS.

Diabetes. 2006 Dec;55(12):3611-9.

11.

Subcongenic analyses reveal complex interactions between distal chromosome 4 genes controlling diabetogenic B cells and CD4 T cells in nonobese diabetic mice.

Stolp J, Chen YG, Cox SL, Henck V, Zhang W, Tsaih SW, Chapman H, Stearns T, Serreze DV, Silveira PA.

J Immunol. 2012 Aug 1;189(3):1406-17. doi: 10.4049/jimmunol.1200120. Epub 2012 Jun 25.

12.

Two genetic loci regulate T cell-dependent islet inflammation and drive autoimmune diabetes pathogenesis.

Fox CJ, Paterson AD, Mortin-Toth SM, Danska JS.

Am J Hum Genet. 2000 Jul;67(1):67-81. Epub 2000 Jun 9.

13.

Signal transduction activator of transcription 5 (STAT5) dysfunction in autoimmune monocytes and macrophages.

Litherland SA, Xie TX, Grebe KM, Davoodi-Semiromi A, Elf J, Belkin NS, Moldawer LL, Clare-Salzler MJ.

J Autoimmun. 2005 Jun;24(4):297-310. Epub 2005 Mar 23.

14.

The influence of the NOD Nss1/Idd5 loci on sialadenitis and gene expression in salivary glands of congenic mice.

Hjelmervik TO, Lindqvist AK, Petersen K, Johannesson M, Stavrum AK, Johansson A, Jonsson R, Holmdahl R, Bolstad AI.

Arthritis Res Ther. 2007;9(5):R99.

15.

Molecular pathway alterations in CD4 T-cells of nonobese diabetic (NOD) mice in the preinsulitis phase of autoimmune diabetes.

Kakoola DN, Curcio-Brint A, Lenchik NI, Gerling IC.

Results Immunol. 2014 May 21;4:30-45. doi: 10.1016/j.rinim.2014.05.001. eCollection 2014.

16.

Two genetic loci independently confer susceptibility to autoimmune gastritis.

Ang DK, Brodnicki TC, Jordan MA, Wilson WE, Silveira P, Gliddon BL, Baxter AG, van Driel IR.

Int Immunol. 2007 Sep;19(9):1135-44. Epub 2007 Aug 13.

PMID:
17698560
17.
18.

M-CSF and GM-CSF regulation of STAT5 activation and DNA binding in myeloid cell differentiation is disrupted in nonobese diabetic mice.

Rumore-Maton B, Elf J, Belkin N, Stutevoss B, Seydel F, Garrigan E, Litherland SA.

Clin Dev Immunol. 2008;2008:769795. doi: 10.1155/2008/769795. Epub 2009 Jan 20.

19.

Heightened interferon-alpha/beta response causes myeloid cell dysfunction and promotes T1D pathogenesis in NOD mice.

Peng RH, Paek E, Xia CQ, Tennyson N, Clare-Salzler MJ.

Ann N Y Acad Sci. 2006 Oct;1079:99-102.

PMID:
17130537
20.

Genetic effects on bone mechanotransduction in congenic mice harboring bone size and strength quantitative trait loci.

Robling AG, Warden SJ, Shultz KL, Beamer WG, Turner CH.

J Bone Miner Res. 2007 Jul;22(7):984-91.

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