Similar articles for PMID: 26497685

Year	Number of Results
1995	1
2000	2
2004	2
2005	3
2006	5
2007	4
2008	2
2009	5
2010	9
2011	12
2012	12
2013	17
2014	9
2015	13
2016	8
2017	10
2018	10
2019	10
2020	4
2021	8
2022	15
2023	4
2024	0

1

The combinatorial activation of the PI3K and Ras/MAPK pathways is sufficient for aggressive tumor formation, while individual pathway activation supports cell persistence.

Thompson KN, Whipple RA, Yoon JR, Lipsky M, Charpentier MS, Boggs AE, Chakrabarti KR, Bhandary L, Hessler LK, Martin SS, Vitolo MI. Thompson KN, et al. Oncotarget. 2015 Nov 3;6(34):35231-46. doi: 10.18632/oncotarget.6159. Oncotarget. 2015. PMID: 26497685 Free PMC article.

2

PTEN expression controls cellular response to cetuximab by mediating PI3K/AKT and RAS/RAF/MAPK downstream signaling in KRAS wild-type, hormone refractory prostate cancer cells.

Bouali S, Chrétien AS, Ramacci C, Rouyer M, Becuwe P, Merlin JL. Bouali S, et al. Oncol Rep. 2009 Mar;21(3):731-5. Oncol Rep. 2009. PMID: 19212633

3

Effects of PTEN Loss and Activated KRAS Overexpression on Mechanical Properties of Breast Epithelial Cells.

Linthicum W, Thanh MH, Vitolo MI, Wen Q. Linthicum W, et al. Int J Mol Sci. 2018 May 30;19(6):1613. doi: 10.3390/ijms19061613. Int J Mol Sci. 2018. PMID: 29848992 Free PMC article.

4

A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors.

Loboda A, Nebozhyn M, Klinghoffer R, Frazier J, Chastain M, Arthur W, Roberts B, Zhang T, Chenard M, Haines B, Andersen J, Nagashima K, Paweletz C, Lynch B, Feldman I, Dai H, Huang P, Watters J. Loboda A, et al. BMC Med Genomics. 2010 Jun 30;3:26. doi: 10.1186/1755-8794-3-26. BMC Med Genomics. 2010. PMID: 20591134 Free PMC article.

5

Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.

McCubrey JA, Steelman LS, Abrams SL, Lee JT, Chang F, Bertrand FE, Navolanic PM, Terrian DM, Franklin RA, D'Assoro AB, Salisbury JL, Mazzarino MC, Stivala F, Libra M. McCubrey JA, et al. Adv Enzyme Regul. 2006;46:249-79. doi: 10.1016/j.advenzreg.2006.01.004. Epub 2006 Jul 18. Adv Enzyme Regul. 2006. PMID: 16854453

6

Combined targeting of MEK/MAPK and PI3K/Akt signalling in multiple myeloma.

Steinbrunn T, Stühmer T, Sayehli C, Chatterjee M, Einsele H, Bargou RC. Steinbrunn T, et al. Br J Haematol. 2012 Nov;159(4):430-40. doi: 10.1111/bjh.12039. Epub 2012 Sep 17. Br J Haematol. 2012. PMID: 22985491 Free article.

7

Single copies of mutant KRAS and mutant PIK3CA cooperate in immortalized human epithelial cells to induce tumor formation.

Wang GM, Wong HY, Konishi H, Blair BG, Abukhdeir AM, Gustin JP, Rosen DM, Denmeade SR, Rasheed Z, Matsui W, Garay JP, Mohseni M, Higgins MJ, Cidado J, Jelovac D, Croessmann S, Cochran RL, Karnan S, Konishi Y, Ota A, Hosokawa Y, Argani P, Lauring J, Park BH. Wang GM, et al. Cancer Res. 2013 Jun 1;73(11):3248-61. doi: 10.1158/0008-5472.CAN-12-1578. Epub 2013 Apr 11. Cancer Res. 2013. PMID: 23580570 Free PMC article.

8

Mutations in FGFR3 and PIK3CA, singly or combined with RAS and AKT1, are associated with AKT but not with MAPK pathway activation in urothelial bladder cancer.

Juanpere N, Agell L, Lorenzo M, de Muga S, López-Vilaró L, Murillo R, Mojal S, Serrano S, Lorente JA, Lloreta J, Hernández S. Juanpere N, et al. Hum Pathol. 2012 Oct;43(10):1573-82. doi: 10.1016/j.humpath.2011.10.026. Epub 2012 Mar 12. Hum Pathol. 2012. PMID: 22417847

9

Exploration of genetic alterations in human endometrial cancer and melanoma: distinct tumorigenic pathways that share a frequent abnormal PI3K/AKT cascade.

Ogawa K, Sun C, Horii A. Ogawa K, et al. Oncol Rep. 2005 Dec;14(6):1481-5. Oncol Rep. 2005. PMID: 16273242

10

PI3K/AKT pathway activation in bladder carcinogenesis.

Calderaro J, Rebouissou S, de Koning L, Masmoudi A, Hérault A, Dubois T, Maille P, Soyeux P, Sibony M, de la Taille A, Vordos D, Lebret T, Radvanyi F, Allory Y. Calderaro J, et al. Int J Cancer. 2014 Apr 15;134(8):1776-84. doi: 10.1002/ijc.28518. Epub 2013 Oct 24. Int J Cancer. 2014. PMID: 24122582 Free article.

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