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Items: 1 to 20 of 81

1.

A limited sampling strategy based on maximum a posteriori Bayesian estimation for a five-probe phenotyping cocktail.

Nguyen TT, Bénech H, Pruvost A, Lenuzza N.

Eur J Clin Pharmacol. 2016 Jan;72(1):39-51.

PMID:
26490357
2.

Combined phenotypic assessment of CYP1A2, CYP2C19, CYP2D6, CYP3A, N-acetyltransferase-2, and xanthine oxidase with the "Cooperstown cocktail".

Streetman DS, Bleakley JF, Kim JS, Nafziger AN, Leeder JS, Gaedigk A, Gotschall R, Kearns GL, Bertino JS Jr.

Clin Pharmacol Ther. 2000 Oct;68(4):375-83.

PMID:
11061577
3.

Evaluation of Mutual Drug-Drug Interaction within Geneva Cocktail for Cytochrome P450 Phenotyping using Innovative Dried Blood Sampling Method.

Bosilkovska M, Samer C, Déglon J, Thomas A, Walder B, Desmeules J, Daali Y.

Basic Clin Pharmacol Toxicol. 2016 Sep;119(3):284-90. doi: 10.1111/bcpt.12586. Epub 2016 Apr 25.

4.

Design optimisation for pharmacokinetic modeling of a cocktail of phenotyping drugs.

Nguyen TT, Bénech H, Delaforge M, Lenuzza N.

Pharm Stat. 2016 Mar-Apr;15(2):165-77. doi: 10.1002/pst.1731. Epub 2015 Dec 22.

PMID:
26689604
5.

Simultaneous determination of tolbutamide, omeprazole, midazolam and dextromethorphan in human plasma by LC-MS/MS--a high throughput approach to evaluate drug-drug interactions.

Zhang W, Han F, Guo P, Zhao H, Lin ZJ, Huang MQ, Bertelsen K, Weng N.

J Chromatogr B Analyt Technol Biomed Life Sci. 2010 May 1;878(15-16):1169-77. doi: 10.1016/j.jchromb.2010.03.026. Epub 2010 Mar 23.

PMID:
20378422
6.

Pharmacokinetic and pharmacodynamic alterations in the Roux-en-Y gastric bypass recipients.

Tandra S, Chalasani N, Jones DR, Mattar S, Hall SD, Vuppalanchi R.

Ann Surg. 2013 Aug;258(2):262-9. doi: 10.1097/SLA.0b013e31827a0e82.

PMID:
23222033
7.

Geneva cocktail for cytochrome p450 and P-glycoprotein activity assessment using dried blood spots.

Bosilkovska M, Samer CF, Déglon J, Rebsamen M, Staub C, Dayer P, Walder B, Desmeules JA, Daali Y.

Clin Pharmacol Ther. 2014 Sep;96(3):349-59. doi: 10.1038/clpt.2014.83. Epub 2014 Apr 10.

8.

Multiplex Phenotyping for Systems Medicine: A One-Point Optimized Practical Sampling Strategy for Simultaneous Estimation of CYP1A2, CYP2C9, CYP2C19, and CYP2D6 Activities Using a Cocktail Approach.

de Andrés F, Terán S, Bovera M, Fariñas H, Terán E, LLerena A.

OMICS. 2016 Feb;20(2):88-96. doi: 10.1089/omi.2015.0131. Epub 2015 Nov 24.

PMID:
26600202
9.

Simultaneous and comprehensive in vivo analysis of cytochrome P450 activity by using a cocktail approach in rats.

Uchida S, Tanaka S, Namiki N.

Biopharm Drug Dispos. 2014 May;35(4):228-36. doi: 10.1002/bdd.1888. Epub 2014 Feb 4.

PMID:
24395703
10.

Cocktail approach for in vivo phenotyping of 5 major CYP450 isoenzymes: development of an effective sampling, extraction, and analytical procedure and pilot study with comparative genotyping.

Wohlfarth A, Naue J, Lutz-Bonengel S, Dresen S, Auwärter V.

J Clin Pharmacol. 2012 Aug;52(8):1200-14. doi: 10.1177/0091270011410570. Epub 2011 Sep 1.

PMID:
21885687
11.

Development of the "Inje cocktail" for high-throughput evaluation of five human cytochrome P450 isoforms in vivo.

Ryu JY, Song IS, Sunwoo YE, Shon JH, Liu KH, Cha IJ, Shin JG.

Clin Pharmacol Ther. 2007 Nov;82(5):531-40. Epub 2007 Mar 28. Erratum in: Clin Pharmacol Ther. 2010 Aug;88(2):275. Dosage error in article text.

PMID:
17392720
12.

Pharmacokinetic assessment of a five-probe cocktail for CYPs 1A2, 2C9, 2C19, 2D6 and 3A.

Turpault S, Brian W, Van Horn R, Santoni A, Poitiers F, Donazzolo Y, Boulenc X.

Br J Clin Pharmacol. 2009 Dec;68(6):928-35. doi: 10.1111/j.1365-2125.2009.03548.x.

13.

Evaluation of modafinil as a perpetrator of metabolic drug-drug interactions using a model informed cocktail reaction phenotyping trial protocol.

Rowland A, van Dyk M, Warncken D, Mangoni AA, Sorich MJ, Rowland A.

Br J Clin Pharmacol. 2018 Mar;84(3):501-509. doi: 10.1111/bcp.13478. Epub 2018 Jan 10.

14.

Pharmacokinetic drug interactions between clobazam and drugs metabolized by cytochrome P450 isoenzymes.

Walzer M, Bekersky I, Blum RA, Tolbert D.

Pharmacotherapy. 2012 Apr;32(4):340-53. doi: 10.1002/j.1875-9114.2012.01028.x. Epub 2012 Mar 15.

PMID:
22422635
15.

Evaluation of felodipine as a potential perpetrator of pharmacokinetic drug-drug interactions.

Snyder BD, Rowland A, Polasek TM, Miners JO, Doogue MP.

Eur J Clin Pharmacol. 2014 Sep;70(9):1115-22. doi: 10.1007/s00228-014-1716-8. Epub 2014 Jul 17.

PMID:
25028073
16.
17.

Evaluation of the drug interaction potential of aplaviroc, a novel human immunodeficiency virus entry inhibitor, using a modified cooperstown 5 + 1 cocktail.

Johnson BM, Song IH, Adkison KK, Borland J, Fang L, Lou Y, Berrey MM, Nafziger AN, Piscitelli SC, Bertino JS Jr.

J Clin Pharmacol. 2006 May;46(5):577-87.

PMID:
16638741
18.

A high-throughput assay using liquid chromatography-tandem mass spectrometry for simultaneous in vivo phenotyping of 5 major cytochrome p450 enzymes in patients.

Ghassabian S, Chetty M, Tattam BN, Chem MC, Glen J, Rahme J, Stankovic Z, Ramzan I, Murray M, McLachlan AJ.

Ther Drug Monit. 2009 Apr;31(2):239-46. doi: 10.1097/FTD.0b013e318197e1bf.

PMID:
19307938
19.

Pharmacokinetic and pharmacodynamic assessment of a five-probe metabolic cocktail for CYPs 1A2, 3A4, 2C9, 2D6 and 2E1.

Blakey GE, Lockton JA, Perrett J, Norwood P, Russell M, Aherne Z, Plume J.

Br J Clin Pharmacol. 2004 Feb;57(2):162-9.

20.

Simultaneous LC-MS/MS quantification of P-glycoprotein and cytochrome P450 probe substrates and their metabolites in DBS and plasma.

Bosilkovska M, Déglon J, Samer C, Walder B, Desmeules J, Staub C, Daali Y.

Bioanalysis. 2014 Jan;6(2):151-64. doi: 10.4155/bio.13.289.

PMID:
24423593

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