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Loss of PTEN expression does not contribute to PDK-1 activity and PKC activation-loop phosphorylation in Jurkat leukaemic T cells.

Freeley M, Park J, Yang KJ, Wange RL, Volkov Y, Kelleher D, Long A.

Cell Signal. 2007 Dec;19(12):2444-57. Epub 2007 Aug 3.


Epidermal growth factor receptor activation protects gastric epithelial cells from Helicobacter pylori-induced apoptosis.

Yan F, Cao H, Chaturvedi R, Krishna U, Hobbs SS, Dempsey PJ, Peek RM Jr, Cover TL, Washington MK, Wilson KT, Polk DB.

Gastroenterology. 2009 Apr;136(4):1297-1307, e1-3. doi: 10.1053/j.gastro.2008.12.059. Epub 2009 Jan 1.


Helicobacter pylori increases proteasome-mediated degradation of p27(kip1) in gastric epithelial cells.

Eguchi H, Herschenhous N, Kuzushita N, Moss SF.

Cancer Res. 2003 Aug 1;63(15):4739-46.


Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343.

Persad S, Attwell S, Gray V, Mawji N, Deng JT, Leung D, Yan J, Sanghera J, Walsh MP, Dedhar S.

J Biol Chem. 2001 Jul 20;276(29):27462-9. Epub 2001 Apr 19.


Activated forms of H-RAS and K-RAS differentially regulate membrane association of PI3K, PDK-1, and AKT and the effect of therapeutic kinase inhibitors on cell survival.

Carón RW, Yacoub A, Li M, Zhu X, Mitchell C, Hong Y, Hawkins W, Sasazuki T, Shirasawa S, Kozikowski AP, Dennis PA, Hagan MP, Grant S, Dent P.

Mol Cancer Ther. 2005 Feb;4(2):257-70.


Elevated phosphorylation and activation of PDK-1/AKT pathway in human breast cancer.

Lin HJ, Hsieh FC, Song H, Lin J.

Br J Cancer. 2005 Dec 12;93(12):1372-81.


VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.

Yu CC, Yang JC, Chang YC, Chuang JG, Lin CW, Wu MS, Chow LP.

PLoS One. 2013;8(1):e55724. doi: 10.1371/journal.pone.0055724. Epub 2013 Jan 31.


Helicobacter pylori regulates cellular migration and apoptosis by activation of phosphatidylinositol 3-kinase signaling.

Nagy TA, Frey MR, Yan F, Israel DA, Polk DB, Peek RM Jr.

J Infect Dis. 2009 Mar 1;199(5):641-51. doi: 10.1086/596660.


Helicobacter pylori Induces Serine Phosphorylation of EGFR via Novel TAK1-p38 Activation Pathway in an HB-EGF-Independent Manner.

Zaidi SF, Refaat A, Zhou Y, Sualeh Muhammad J, Shin MS, Saiki I, Sakurai H, Sugiyama T.

Helicobacter. 2015 Oct;20(5):381-9. doi: 10.1111/hel.12215. Epub 2015 Feb 23.


Inhibition of PDK-1 activity causes a reduction in cell proliferation and survival.

Flynn P, Wongdagger M, Zavar M, Dean NM, Stokoe D.

Curr Biol. 2000 Nov 16;10(22):1439-42.


3'-phosphoinositide-dependent kinase-1 (PDK-1) in PI 3-kinase signaling.

Storz P, Toker A.

Front Biosci. 2002 Apr 1;7:d886-902. Review.


Molecular mechanisms of the diabetogenic effects of arsenic: inhibition of insulin signaling by arsenite and methylarsonous acid.

Paul DS, Harmon AW, Devesa V, Thomas DJ, Stýblo M.

Environ Health Perspect. 2007 May;115(5):734-42. Epub 2007 Jan 29.


Regulation of protein kinase C zeta by PI 3-kinase and PDK-1.

Chou MM, Hou W, Johnson J, Graham LK, Lee MH, Chen CS, Newton AC, Schaffhausen BS, Toker A.

Curr Biol. 1998 Sep 24;8(19):1069-77.


Integrin-linked kinase modulates lipopolysaccharide- and Helicobacter pylori-induced nuclear factor κB-activated tumor necrosis factor-α production via regulation of p65 serine 536 phosphorylation.

Ahmed AU, Sarvestani ST, Gantier MP, Williams BR, Hannigan GE.

J Biol Chem. 2014 Oct 3;289(40):27776-93. doi: 10.1074/jbc.M114.574541. Epub 2014 Aug 6.


NF-kappaB activation by Helicobacter pylori requires Akt-mediated phosphorylation of p65.

Takeshima E, Tomimori K, Kawakami H, Ishikawa C, Sawada S, Tomita M, Senba M, Kinjo F, Mimuro H, Sasakawa C, Fujita J, Mori N.

BMC Microbiol. 2009 Feb 12;9:36. doi: 10.1186/1471-2180-9-36. Retraction in: BMC Microbiol. 2011;11:128.


Helicobacter pylori CagA upregulation of CIP2A is dependent on the Src and MEK/ERK pathways.

Zhao D, Liu Z, Ding J, Li W, Sun Y, Yu H, Zhou Y, Zeng J, Chen C, Jia J.

J Med Microbiol. 2010 Mar;59(Pt 3):259-65. doi: 10.1099/jmm.0.014704-0. Epub 2009 Dec 3.


Membrane localization of 3-phosphoinositide-dependent protein kinase-1 stimulates activities of Akt and atypical protein kinase C but does not stimulate glucose transport and glycogen synthesis in 3T3-L1 adipocytes.

Egawa K, Maegawa H, Shi K, Nakamura T, Obata T, Yoshizaki T, Morino K, Shimizu S, Nishio Y, Suzuki E, Kashiwagi A.

J Biol Chem. 2002 Oct 11;277(41):38863-9. Epub 2002 Jul 29.


Interaction between the Helicobacter pylori CagA and alpha-Pix in gastric epithelial AGS cells.

Baek HY, Lim JW, Kim H.

Ann N Y Acad Sci. 2007 Jan;1096:18-23.


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