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Items: 1 to 20 of 48

1.

Inhibition of Super-Enhancer Activity in Autoinflammatory Site-Derived T Cells Reduces Disease-Associated Gene Expression.

Peeters JG, Vervoort SJ, Tan SC, Mijnheer G, de Roock S, Vastert SJ, Nieuwenhuis EE, van Wijk F, Prakken BJ, Creyghton MP, Coffer PJ, Mokry M, van Loosdregt J.

Cell Rep. 2015 Sep 29;12(12):1986-96. doi: 10.1016/j.celrep.2015.08.046. Epub 2015 Sep 17.

2.
3.

Anti-tumor necrosis factor α targets protein kinase B/c-Akt-induced resistance of effector cells to suppression in juvenile idiopathic arthritis.

Wehrens EJ, Vastert SJ, Mijnheer G, Meerding J, Klein M, Wulffraat NM, Prakken BJ, van Wijk F.

Arthritis Rheum. 2013 Dec;65(12):3279-84. doi: 10.1002/art.38132.

4.

Hypoxic synovial environment and expression of macrophage inflammatory protein 3gamma/CCL20 in juvenile idiopathic arthritis.

Bosco MC, Delfino S, Ferlito F, Battaglia F, Puppo M, Gregorio A, Gambini C, Gattorno M, Martini A, Varesio L.

Arthritis Rheum. 2008 Jun;58(6):1833-8. doi: 10.1002/art.23516.

5.

Increased autophagy contributes to the inflammatory phenotype of juvenile idiopathic arthritis synovial fluid T cells.

Peeters JGC, de Graeff N, Lotz M, Albani S, de Roock S, van Loosdregt J.

Rheumatology (Oxford). 2017 Oct 1;56(10):1694-1699. doi: 10.1093/rheumatology/kex227.

6.

Th17 transcription factor RORC2 is inversely correlated with FOXP3 expression in the joints of children with juvenile idiopathic arthritis.

Olivito B, Simonini G, Ciullini S, Moriondo M, Betti L, Gambineri E, Cantarini L, De Martino M, Azzari C, Cimaz R.

J Rheumatol. 2009 Sep;36(9):2017-24. doi: 10.3899/jrheum.090066. Epub 2009 Jul 31.

PMID:
19648312
8.

Oligoclonal expansion of T cells in persistent oligoarticular juvenile idiopathic arthritis.

Brunner J, Herrmann M, Metzler M, Gaipl U, Reuter G, Haas JP.

Clin Exp Rheumatol. 2010 Jul-Aug;28(4):592-3. Epub 2010 Aug 31. No abstract available.

PMID:
20659414
9.

BET-bromodomain inhibitors modulate epigenetic patterns at the diacylglycerol kinase alpha enhancer associated with radiation-induced fibrosis.

Valinciute G, Weigel C, Veldwijk MR, Oakes CC, Herskind C, Wenz F, Plass C, Schmezer P, Popanda O.

Radiother Oncol. 2017 Oct;125(1):168-174. doi: 10.1016/j.radonc.2017.08.028. Epub 2017 Sep 12.

PMID:
28916223
10.

Network analysis identifies protein clusters of functional importance in juvenile idiopathic arthritis.

Stevens A, Meyer S, Hanson D, Clayton P, Donn RP.

Arthritis Res Ther. 2014 May 8;16(3):R109. doi: 10.1186/ar4559.

12.

Selective elimination of pathogenic synovial fluid T-cells from rheumatoid arthritis and juvenile idiopathic arthritis by targeted activation of Fas-apoptotic signaling.

Bremer E, Abdulahad WH, de Bruyn M, Samplonius DF, Kallenberg CG, Armbrust W, Brouwers E, Wajant H, Helfrich W.

Immunol Lett. 2011 Aug 30;138(2):161-8. doi: 10.1016/j.imlet.2011.04.004. Epub 2011 Apr 15.

PMID:
21514322
13.

Methotrexate treatment affects effector but not regulatory T cells in juvenile idiopathic arthritis.

Bulatović Ćalasan M, Vastert SJ, Scholman RC, Verweij F, Klein M, Wulffraat NM, Prakken BJ, van Wijk F.

Rheumatology (Oxford). 2015 Sep;54(9):1724-34. doi: 10.1093/rheumatology/kev101. Epub 2015 Apr 14.

PMID:
25877908
14.

The transcription factor CREM drives an inflammatory phenotype of T cells in oligoarticular juvenile idiopathic arthritis.

Ohl K, Nickel H, Moncrieffe H, Klemm P, Scheufen A, Föll D, Wixler V, Schippers A, Wagner N, Wedderburn LR, Tenbrock K.

Pediatr Rheumatol Online J. 2018 Jun 20;16(1):39. doi: 10.1186/s12969-018-0253-x.

15.

Phenotypic and functional characterisation of CCR7+ and CCR7- CD4+ memory T cells homing to the joints in juvenile idiopathic arthritis.

Gattorno M, Prigione I, Morandi F, Gregorio A, Chiesa S, Ferlito F, Favre A, Uccelli A, Gambini C, Martini A, Pistoia V.

Arthritis Res Ther. 2005;7(2):R256-67. Epub 2005 Jan 12.

16.

Sequence specific binding of Ets-1 to the mouse cytokeratin EndoA gene enhancer.

Hamazato F, Fujimura Y, Tamai Y, Takemoto Y, Matsushiro A, Nozaki M.

Biochem Biophys Res Commun. 1993 Apr 30;192(2):430-8.

PMID:
7683460
17.

Self-Sustained Resistance to Suppression of CD8+ Teff Cells at the Site of Autoimmune Inflammation Can Be Reversed by Tumor Necrosis Factor and Interferon-γ Blockade.

Petrelli A, Wehrens EJ, Scholman RC, Prakken BJ, Vastert SJ, van Wijk F.

Arthritis Rheumatol. 2016 Jan;68(1):229-36. doi: 10.1002/art.39418.

18.

Common and specific signatures of gene expression and protein-protein interactions in autoimmune diseases.

Tuller T, Atar S, Ruppin E, Gurevich M, Achiron A.

Genes Immun. 2013 Mar;14(2):67-82. doi: 10.1038/gene.2012.55. Epub 2012 Nov 29.

PMID:
23190644
19.

Synovial and peripheral blood CD4+FoxP3+ T cells in spondyloarthritis.

Appel H, Wu P, Scheer R, Kedor C, Sawitzki B, Thiel A, Radbruch A, Sieper J, Syrbe U.

J Rheumatol. 2011 Nov;38(11):2445-51. doi: 10.3899/jrheum.110377. Epub 2011 Sep 15.

PMID:
21921098
20.

Dual role of anti-TNF therapy: enhancement of TCR-mediated T cell activation in peripheral blood and inhibition of inflammation in target tissues.

Bosè F, Raeli L, Garutti C, Frigerio E, Cozzi A, Crimi M, Caprioli F, Scavelli R, Altomare G, Geginat J, Abrignani S, Reali E.

Clin Immunol. 2011 May;139(2):164-76. doi: 10.1016/j.clim.2011.01.015. Epub 2011 Jan 31.

PMID:
21334981

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