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Items: 1 to 20 of 142

1.

The Plasmodium translocon of exported proteins component EXP2 is critical for establishing a patent malaria infection in mice.

Kalanon M, Bargieri D, Sturm A, Matthews K, Ghosh S, Goodman CD, Thiberge S, Mollard V, McFadden GI, Ménard R, de Koning-Ward TF.

Cell Microbiol. 2016 Mar;18(3):399-412. doi: 10.1111/cmi.12520. Epub 2015 Oct 14.

PMID:
26347246
2.

Two putative protein export regulators promote Plasmodium blood stage development in vivo.

Matz JM, Matuschewski K, Kooij TW.

Mol Biochem Parasitol. 2013 Sep;191(1):44-52. doi: 10.1016/j.molbiopara.2013.09.003. Epub 2013 Sep 25.

PMID:
24076174
3.

PTEX is an essential nexus for protein export in malaria parasites.

Elsworth B, Matthews K, Nie CQ, Kalanon M, Charnaud SC, Sanders PR, Chisholm SA, Counihan NA, Shaw PJ, Pino P, Chan JA, Azevedo MF, Rogerson SJ, Beeson JG, Crabb BS, Gilson PR, de Koning-Ward TF.

Nature. 2014 Jul 31;511(7511):587-91. doi: 10.1038/nature13555. Epub 2014 Jul 16.

PMID:
25043043
4.

Uncoupling the Threading and Unfoldase Actions of Plasmodium HSP101 Reveals Differences in Export between Soluble and Insoluble Proteins.

Matthews KM, Kalanon M, de Koning-Ward TF.

MBio. 2019 Jun 4;10(3). pii: e01106-19. doi: 10.1128/mBio.01106-19.

5.

The Plasmodium berghei translocon of exported proteins reveals spatiotemporal dynamics of tubular extensions.

Matz JM, Goosmann C, Brinkmann V, Grützke J, Ingmundson A, Matuschewski K, Kooij TW.

Sci Rep. 2015 Jul 29;5:12532. doi: 10.1038/srep12532.

6.

PTEX component HSP101 mediates export of diverse malaria effectors into host erythrocytes.

Beck JR, Muralidharan V, Oksman A, Goldberg DE.

Nature. 2014 Jul 31;511(7511):592-5. doi: 10.1038/nature13574. Epub 2014 Jul 16.

7.

The Plasmodium translocon of exported proteins (PTEX) component thioredoxin-2 is important for maintaining normal blood-stage growth.

Matthews K, Kalanon M, Chisholm SA, Sturm A, Goodman CD, Dixon MW, Sanders PR, Nebl T, Fraser F, Haase S, McFadden GI, Gilson PR, Crabb BS, de Koning-Ward TF.

Mol Microbiol. 2013 Sep;89(6):1167-86. doi: 10.1111/mmi.12334. Epub 2013 Aug 15.

8.

Spatial organization of protein export in malaria parasite blood stages.

Charnaud SC, Jonsdottir TK, Sanders PR, Bullen HE, Dickerman BK, Kouskousis B, Palmer CS, Pietrzak HM, Laumaea AE, Erazo AB, McHugh E, Tilley L, Crabb BS, Gilson PR.

Traffic. 2018 Aug;19(8):605-623. doi: 10.1111/tra.12577. Epub 2018 May 23.

9.

Expression and characterization of the Plasmodium translocon of the exported proteins component EXP2.

Hakamada K, Watanabe H, Kawano R, Noguchi K, Yohda M.

Biochem Biophys Res Commun. 2017 Jan 22;482(4):700-705. doi: 10.1016/j.bbrc.2016.11.097. Epub 2016 Nov 16.

PMID:
27865834
10.

Proteomic and genetic analyses demonstrate that Plasmodium berghei blood stages export a large and diverse repertoire of proteins.

Pasini EM, Braks JA, Fonager J, Klop O, Aime E, Spaccapelo R, Otto TD, Berriman M, Hiss JA, Thomas AW, Mann M, Janse CJ, Kocken CH, Franke-Fayard B.

Mol Cell Proteomics. 2013 Feb;12(2):426-48. doi: 10.1074/mcp.M112.021238. Epub 2012 Nov 28.

11.

Knockdown of the translocon protein EXP2 in Plasmodium falciparum reduces growth and protein export.

Charnaud SC, Kumarasingha R, Bullen HE, Crabb BS, Gilson PR.

PLoS One. 2018 Nov 15;13(11):e0204785. doi: 10.1371/journal.pone.0204785. eCollection 2018.

12.

A newly discovered protein export machine in malaria parasites.

de Koning-Ward TF, Gilson PR, Boddey JA, Rug M, Smith BJ, Papenfuss AT, Sanders PR, Lundie RJ, Maier AG, Cowman AF, Crabb BS.

Nature. 2009 Jun 18;459(7249):945-9. doi: 10.1038/nature08104.

13.

Biosynthesis, localization, and macromolecular arrangement of the Plasmodium falciparum translocon of exported proteins (PTEX).

Bullen HE, Charnaud SC, Kalanon M, Riglar DT, Dekiwadia C, Kangwanrangsan N, Torii M, Tsuboi T, Baum J, Ralph SA, Cowman AF, de Koning-Ward TF, Crabb BS, Gilson PR.

J Biol Chem. 2012 Mar 9;287(11):7871-84. doi: 10.1074/jbc.M111.328591. Epub 2012 Jan 17.

14.

Stable Translocation Intermediates Jam Global Protein Export in Plasmodium falciparum Parasites and Link the PTEX Component EXP2 with Translocation Activity.

Mesén-Ramírez P, Reinsch F, Blancke Soares A, Bergmann B, Ullrich AK, Tenzer S, Spielmann T.

PLoS Pathog. 2016 May 11;12(5):e1005618. doi: 10.1371/journal.ppat.1005618. eCollection 2016 May.

15.

Plasmodium species: master renovators of their host cells.

de Koning-Ward TF, Dixon MW, Tilley L, Gilson PR.

Nat Rev Microbiol. 2016 Aug;14(8):494-507. doi: 10.1038/nrmicro.2016.79. Epub 2016 Jul 4. Review.

PMID:
27374802
16.

EXP2 is a nutrient-permeable channel in the vacuolar membrane of Plasmodium and is essential for protein export via PTEX.

Garten M, Nasamu AS, Niles JC, Zimmerberg J, Goldberg DE, Beck JR.

Nat Microbiol. 2018 Oct;3(10):1090-1098. doi: 10.1038/s41564-018-0222-7. Epub 2018 Aug 27.

17.

Functional evaluation of Plasmodium export signals in Plasmodium berghei suggests multiple modes of protein export.

Sijwali PS, Rosenthal PJ.

PLoS One. 2010 Apr 19;5(4):e10227. doi: 10.1371/journal.pone.0010227.

18.

The N-terminus of EXP2 forms the membrane-associated pore of the protein exporting translocon PTEX in Plasmodium falciparum.

Sanders PR, Dickerman BK, Charnaud SC, Ramsland PA, Crabb BS, Gilson PR.

J Biochem. 2019 Mar 1;165(3):239-248. doi: 10.1093/jb/mvy099.

PMID:
30476118
19.

Host erythrocyte environment influences the localization of exported protein 2, an essential component of the Plasmodium translocon.

Meibalan E, Comunale MA, Lopez AM, Bergman LW, Mehta A, Vaidya AB, Burns JM Jr.

Eukaryot Cell. 2015 Apr;14(4):371-84. doi: 10.1128/EC.00228-14. Epub 2015 Feb 6.

20.

The malaria PTEX component PTEX88 interacts most closely with HSP101 at the host-parasite interface.

Chisholm SA, Kalanon M, Nebl T, Sanders PR, Matthews KM, Dickerman BK, Gilson PR, de Koning-Ward TF.

FEBS J. 2018 Jun;285(11):2037-2055. doi: 10.1111/febs.14463. Epub 2018 Apr 20.

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