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Items: 1 to 20 of 117


A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status.

Sood S, Gallagher IJ, Lunnon K, Rullman E, Keohane A, Crossland H, Phillips BE, Cederholm T, Jensen T, van Loon LJ, Lannfelt L, Kraus WE, Atherton PJ, Howard R, Gustafsson T, Hodges A, Timmons JA.

Genome Biol. 2015 Sep 7;16:185. doi: 10.1186/s13059-015-0750-x.


Transcriptional profiling of human familial longevity indicates a role for ASF1A and IL7R.

Passtoors WM, Boer JM, Goeman JJ, Akker EB, Deelen J, Zwaan BJ, Scarborough A, Breggen Rv, Vossen RH, Houwing-Duistermaat JJ, Ommen GJ, Westendorp RG, van Heemst D, de Craen AJ, White AJ, Gunn DA, Beekman M, Slagboom PE.

PLoS One. 2012;7(1):e27759. doi: 10.1371/journal.pone.0027759. Epub 2012 Jan 11. Erratum in: PLoS One. 2012;7(5): doi/10.1371/annotation/d4d3b1fb-35e0-4c4d-89bc-e6a839504e54.


Rates of diagnostic transition and cognitive change at 18-month follow-up among 1,112 participants in the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing (AIBL).

Ellis KA, Szoeke C, Bush AI, Darby D, Graham PL, Lautenschlager NT, Macaulay SL, Martins RN, Maruff P, Masters CL, McBride SJ, Pike KE, Rainey-Smith SR, Rembach A, Robertson J, Rowe CC, Savage G, Villemagne VL, Woodward M, Wilson W, Zhang P, Ames D; AIBL Research Group.

Int Psychogeriatr. 2014 Apr;26(4):543-54. doi: 10.1017/S1041610213001956. Epub 2013 Nov 20.


A gene expression pattern in blood for the early detection of Alzheimer's disease.

Booij BB, Lindahl T, Wetterberg P, Skaane NV, Sæbø S, Feten G, Rye PD, Kristiansen LI, Hagen N, Jensen M, Bårdsen K, Winblad B, Sharma P, Lönneborg A.

J Alzheimers Dis. 2011;23(1):109-19. doi: 10.3233/JAD-2010-101518.


Age and disease related changes in the translocator protein (TSPO) system in the human brain: positron emission tomography measurements with [11C]vinpocetine.

Gulyás B, Vas A, Tóth M, Takano A, Varrone A, Cselényi Z, Schain M, Mattsson P, Halldin C.

Neuroimage. 2011 Jun 1;56(3):1111-21. doi: 10.1016/j.neuroimage.2011.02.020. Epub 2011 Feb 12.


ApoE4 effects on automated diagnostic classifiers for mild cognitive impairment and Alzheimer's disease.

Apostolova LG, Hwang KS, Kohannim O, Avila D, Elashoff D, Jack CR Jr, Shaw L, Trojanowski JQ, Weiner MW, Thompson PM; Alzheimer's Disease Neuroimaging Initiative.

Neuroimage Clin. 2014 Jan 4;4:461-72. doi: 10.1016/j.nicl.2013.12.012. eCollection 2014.


Sputum gene expression signature of 6 biomarkers discriminates asthma inflammatory phenotypes.

Baines KJ, Simpson JL, Wood LG, Scott RJ, Fibbens NL, Powell H, Cowan DC, Taylor DR, Cowan JO, Gibson PG.

J Allergy Clin Immunol. 2014 Apr;133(4):997-1007. doi: 10.1016/j.jaci.2013.12.1091. Epub 2014 Feb 28.


Lack of reliable evidence for a distinctive ε4-related cognitive phenotype that is independent from clinical diagnostic status: findings from the Australian Imaging, Biomarkers and Lifestyle Study.

Foster JK, Albrecht MA, Savage G, Lautenschlager NT, Ellis KA, Maruff P, Szoeke C, Taddei K, Martins R, Masters CL, Ames D; AIBL Research Group.

Brain. 2013 Jul;136(Pt 7):2201-16. doi: 10.1093/brain/awt127. Epub 2013 Jun 3.


Skin differences based on age and chronicity of ultraviolet exposure: results from a gene expression profiling study.

McGrath JA, Robinson MK, Binder RL.

Br J Dermatol. 2012 Jun;166 Suppl 2:9-15. doi: 10.1111/j.1365-2133.2012.10860.x.


Molecular networks of human muscle adaptation to exercise and age.

Phillips BE, Williams JP, Gustafsson T, Bouchard C, Rankinen T, Knudsen S, Smith K, Timmons JA, Atherton PJ.

PLoS Genet. 2013 Mar;9(3):e1003389. doi: 10.1371/journal.pgen.1003389. Epub 2013 Mar 21. Erratum in: PLoS Genet. 2013;9(4). doi: 10.1371/annotation/0dd3671e-1460-48fa-9d6a-2865dce78c07.


Genetic Analysis of Association Between Calcium Signaling and Hippocampal Activation, Memory Performance in the Young and Old, and Risk for Sporadic Alzheimer Disease.

Heck A, Fastenrath M, Coynel D, Auschra B, Bickel H, Freytag V, Gschwind L, Hartmann F, Jessen F, Kaduszkiewicz H, Maier W, Milnik A, Pentzek M, Riedel-Heller SG, Spalek K, Vogler C, Wagner M, Weyerer S, Wolfsgruber S, de Quervain DJ, Papassotiropoulos A.

JAMA Psychiatry. 2015 Oct;72(10):1029-36. doi: 10.1001/jamapsychiatry.2015.1309.


Evolutionary conserved longevity genes and human cognitive abilities in elderly cohorts.

Lopez LM, Harris SE, Luciano M, Liewald D, Davies G, Gow AJ, Tenesa A, Payton A, Ke X, Whalley LJ, Fox H, Haggerty P, Ollier W, Pickles A, Porteous DJ, Horan MA, Pendleton N, Starr JM, Deary IJ.

Eur J Hum Genet. 2012 Mar;20(3):341-7. doi: 10.1038/ejhg.2011.201. Epub 2011 Nov 2.


Healthy ageing in the Nun Study: definition and neuropathologic correlates.

Tyas SL, Snowdon DA, Desrosiers MF, Riley KP, Markesbery WR.

Age Ageing. 2007 Nov;36(6):650-5. Epub 2007 Sep 28.


B-Vitamin Intake and Biomarker Status in Relation to Cognitive Decline in Healthy Older Adults in a 4-Year Follow-Up Study.

Hughes CF, Ward M, Tracey F, Hoey L, Molloy AM, Pentieva K, McNulty H.

Nutrients. 2017 Jan 10;9(1). pii: E53. doi: 10.3390/nu9010053.


Towards ageing well: Use it or lose it: Exercise, epigenetics and cognition.

Rea IM.

Biogerontology. 2017 Aug;18(4):679-691. doi: 10.1007/s10522-017-9719-3. Epub 2017 Jun 17.


Alzheimer and vascular dementias and driving. A prospective road and laboratory study.

Fitten LJ, Perryman KM, Wilkinson CJ, Little RJ, Burns MM, Pachana N, Mervis JR, Malmgren R, Siembieda DW, Ganzell S.

JAMA. 1995 May 3;273(17):1360-5.


Kicking Back Cognitive Ageing: Leg Power Predicts Cognitive Ageing after Ten Years in Older Female Twins.

Steves CJ, Mehta MM, Jackson SH, Spector TD.

Gerontology. 2016;62(2):138-49. doi: 10.1159/000441029. Epub 2015 Nov 10.


Predicting Alzheimer disease with β-amyloid imaging: results from the Australian imaging, biomarkers, and lifestyle study of ageing.

Rowe CC, Bourgeat P, Ellis KA, Brown B, Lim YY, Mulligan R, Jones G, Maruff P, Woodward M, Price R, Robins P, Tochon-Danguy H, O'Keefe G, Pike KE, Yates P, Szoeke C, Salvado O, Macaulay SL, O'Meara T, Head R, Cobiac L, Savage G, Martins R, Masters CL, Ames D, Villemagne VL.

Ann Neurol. 2013 Dec;74(6):905-13. doi: 10.1002/ana.24040.


Towards a multidimensional healthy ageing phenotype.

Mount S, Lara J, Schols AM, Mathers JC.

Curr Opin Clin Nutr Metab Care. 2016 Nov;19(6):418-426. Review.


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