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26295576,33051372,25911225,27473315,32019798,31068436,19090038,31217305,17981060,28442603,26878695,33010083,32938702,28611248,32005734,33402536,18608886,32487759,27706915,33177217,30279286,29150592,20656913,24779420,24361821,30755510,23355008,27603677,19220748,21527474,25083783,35107385,21883519,19715768,22028661,32019801,18456861,27538790,27068092,33201436,25597841,31887136,20545865,30205199,33705521,26051489,20452278,28120495,34663092,16531086,16861675,34311583,31131706,34399627,15813678,30538182,30052103,23264643,22220813,18227163,25345444,30698898,31717953,21217201,19703288,31026268,33173002,17501924,16956378,20675576,18708564,28753224,15322014,22345349,21178435,21658997,23022264,21784698,25534941,28174315,30914505,28677124,30139746,31100153,26991818,26605426,33917505,27548283,34722342,17406869,16672465,20439478,23031507,27652896,16110797,15052376,17542914,25196896,24614084,32071276,31757831,34878292,24244155,34579578,27191378,29067690,19917717,32461274,26529322,28453536,20214686,21724450,21091509,25582336,23161019,21490150,31694453,29370403,27649508,24429506,30880633,19822220,30446390,31380304,23104569,17176258,24945802,28489963,24009505,18552284,25724996,16990036,26365385,33323509,25153325,19889083,27801871,29323188,23087369,32269156,31817957,23785510,33028685,31290538,26953327,26854126,12704156,31366710,32667960,30833675,29170805,19429746,27321585,33897671,34524893,22163332,28515264,21062375,19132084,21178506,9669338,20966095,30552790,29248112,25687931,20097742,35972528,11913767,23527074,30251593,30927289,32398317,24568630,30971734,35913157,16205968,9393803,25943523,21210869,26749442,18443090,17601876,26920882,27841851,24189125,7960101,18606827,9923518,18249572,17905922,16804168,27624005,32418035,27651362,20974273,26356475,30292408,25536999,34638975,28701066,29113011,28803907,32873705,27939177,9832321,12146755,20348388,16110796,27687755,28840304,21926329,29423632,30066670,11446528,25932027,28992243,31941812,22562470,25820520,20370364,27816905,27609562,21183690,19028996,33331054,19389762,32812643,26197240,23532976,22675534,10931287,29179120,17845073,22649543,32117802,23584992,18830711,35982778,22083709,19564390,18757806,22058140,22108383,24814063,27816786,29213115,29114981,15075285,32407390,30455681,18599824,25118871,28888885,31424155,28831166,30692551,36719915,26787716,26311470,31284857,22328399,16110787,33780518,27155139,10718844,23563483,30286953,33045305,29848910,12734751,25375670,18689526,32385534,7847892,22678624,31602821,33475797,29084744,32743127,30639305,23676908,12172968,23599423,26342082,18539819,36835119,9620950,25908096,18538268,23185496,24612080,23028460,23209763,29345613,33629421,25084861,23801335,17921349,9229335,32341126,22046314,19893627,28215034,29202712,25329394,30120327,23870253,30842778,15504822,34544876,21724936,29577051,36625602,20363898,22443190,18490465,31134001,29222113,30450827,16110790,30543319,8028645,31416836,12136012,33946853,31192161,25107308,34299357,29911293,21412410,28423062,19124579,23750903,27584150,36768506,31018527,770331,8926121,34468270,19717745,33405042,34798270,21206755,29299840,30072493,27303716,27016805,27524240,33051366,35638742,35941233,31342212,36893734,32265325,32171003,27019389,27889463,20421382,27264789,29109714,29403452,32378777,30971696,28058997,34956933,36094091,33593906,31525190,29467298,31105662,28652019,31887194,21768277,33424809,35080469,30692984,29849062,34632721,24906414,31079330,23346079,19383006,28647921,33405039,27921081,11865299,27820672,25309516,30972049,29371582,27028978,16040966,31263942,30402129,29604490,26492565,27433157,10523272,21178441,29371494,23631920,35448585,10920389,30483221,22808335,35628691,32153523,32457716,27622208,35049996,37140471,32106242,28381925,33126739,29385695,10824201,32391495,36389145,25767465,23819394,30408941,23430083,30941108,30245896,35127559,31554729,11134062,30810017,30810019,30810018[uid]

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The Aspergillus fumigatus pkcA G579R Mutant Is Defective in the Activation of the Cell Wall Integrity Pathway but Is Dispensable for Virulence in a Neutropenic Mouse Infection Model.

Rocha MC, Godoy KF, de Castro PA, Hori JI, Bom VL, Brown NA, Cunha AF, Goldman GH, Malavazi I. Rocha MC, et al. PLoS One. 2015 Aug 21;10(8):e0135195. doi: 10.1371/journal.pone.0135195. eCollection 2015. PLoS One. 2015. PMID: 26295576 Free PMC article.

Aspergillus fumigatus G-Protein Coupled Receptors GprM and GprJ Are Important for the Regulation of the Cell Wall Integrity Pathway, Secondary Metabolite Production, and Virulence.

Filho APDC, Brancini GTP, de Castro PA, Valero C, Ferreira Filho JA, Silva LP, Rocha MC, Malavazi I, Pontes JGM, Fill T, Silva RN, Almeida F, Steenwyk JL, Rokas A, Dos Reis TF, Ries LNA, Goldman GH. Filho APDC, et al. mBio. 2020 Oct 13;11(5):e02458-20. doi: 10.1128/mBio.02458-20. mBio. 2020. PMID: 33051372 Free PMC article.

The Aspergillus fumigatus sitA Phosphatase Homologue Is Important for Adhesion, Cell Wall Integrity, Biofilm Formation, and Virulence.

Bom VL, de Castro PA, Winkelströter LK, Marine M, Hori JI, Ramalho LN, dos Reis TF, Goldman MH, Brown NA, Rajendran R, Ramage G, Walker LA, Munro CA, Rocha MC, Malavazi I, Hagiwara D, Goldman GH. Bom VL, et al. Eukaryot Cell. 2015 Aug;14(8):728-44. doi: 10.1128/EC.00008-15. Epub 2015 Apr 24. Eukaryot Cell. 2015. PMID: 25911225 Free PMC article.

Aspergillus fumigatus MADS-Box Transcription Factor rlmA Is Required for Regulation of the Cell Wall Integrity and Virulence.

Rocha MC, Fabri JH, Franco de Godoy K, Alves de Castro P, Hori JI, Ferreira da Cunha A, Arentshorst M, Ram AF, van den Hondel CA, Goldman GH, Malavazi I. Rocha MC, et al. G3 (Bethesda). 2016 Sep 8;6(9):2983-3002. doi: 10.1534/g3.116.031112. G3 (Bethesda). 2016. PMID: 27473315 Free PMC article.

The Aspergillus fumigatus Phosphoproteome Reveals Roles of High-Osmolarity Glycerol Mitogen-Activated Protein Kinases in Promoting Cell Wall Damage and Caspofungin Tolerance.

Mattos EC, Silva LP, Valero C, de Castro PA, Dos Reis TF, Ribeiro LFC, Marten MR, Silva-Rocha R, Westmann C, da Silva CHTP, Taft CA, Al-Furaiji N, Bromley M, Mortensen UH, Benz JP, Brown NA, Goldman GH. Mattos EC, et al. mBio. 2020 Feb 4;11(1):e02962-19. doi: 10.1128/mBio.02962-19. mBio. 2020. PMID: 32019798 Free PMC article.

An Ssd1 Homolog Impacts Trehalose and Chitin Biosynthesis and Contributes to Virulence in Aspergillus fumigatus.

Thammahong A, Dhingra S, Bultman KM, Kerkaert JD, Cramer RA. Thammahong A, et al. mSphere. 2019 May 8;4(3):e00244-19. doi: 10.1128/mSphere.00244-19. mSphere. 2019. PMID: 31068436 Free PMC article.

Afcwh41 is required for cell wall synthesis, conidiation, and polarity in Aspergillus fumigatus.

Zhang L, Zhou H, Ouyang H, Li Y, Jin C. Zhang L, et al. FEMS Microbiol Lett. 2008 Dec;289(2):155-65. doi: 10.1111/j.1574-6968.2008.01376.x. FEMS Microbiol Lett. 2008. PMID: 19090038

The Aspergillus fumigatus Mucin MsbA Regulates the Cell Wall Integrity Pathway and Controls Recognition of the Fungus by the Immune System.

Gurgel ILDS, Jorge KTOS, Malacco NLSO, Souza JAM, Rocha MC, Fernandes MF, Martins FRB, Malavazi I, Teixeira MM, Soriani FM. Gurgel ILDS, et al. mSphere. 2019 Jun 19;4(3):e00350-19. doi: 10.1128/mSphere.00350-19. mSphere. 2019. PMID: 31217305 Free PMC article.

The mitogen-activated protein kinase MpkA of Aspergillus fumigatus regulates cell wall signaling and oxidative stress response.

Valiante V, Heinekamp T, Jain R, Härtl A, Brakhage AA. Valiante V, et al. Fungal Genet Biol. 2008 May;45(5):618-27. doi: 10.1016/j.fgb.2007.09.006. Epub 2007 Sep 25. Fungal Genet Biol. 2008. PMID: 17981060

Aspergillus fumigatus Trehalose-Regulatory Subunit Homolog Moonlights To Mediate Cell Wall Homeostasis through Modulation of Chitin Synthase Activity.

Thammahong A, Caffrey-Card AK, Dhingra S, Obar JJ, Cramer RA. Thammahong A, et al. mBio. 2017 Apr 25;8(2):e00056-17. doi: 10.1128/mBio.00056-17. mBio. 2017. PMID: 28442603 Free PMC article.

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