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Items: 1 to 20 of 103


Alpha7 nicotinic acetylcholine receptor is required for blood-brain barrier injury-related CNS disorders caused by Cryptococcus neoformans and HIV-1 associated comorbidity factors.

Zhang B, Yu JY, Liu LQ, Peng L, Chi F, Wu CH, Jong A, Wang SF, Cao H, Huang SH.

BMC Infect Dis. 2015 Aug 19;15:352. doi: 10.1186/s12879-015-1075-9.


CD44-mediated monocyte transmigration across Cryptococcus neoformans-infected brain microvascular endothelial cells is enhanced by HIV-1 gp41-I90 ectodomain.

He X, Shi X, Puthiyakunnon S, Zhang L, Zeng Q, Li Y, Boddu S, Qiu J, Lai Z, Ma C, Xie Y, Long M, Du L, Huang SH, Cao H.

J Biomed Sci. 2016 Feb 20;23:28. doi: 10.1186/s12929-016-0247-2.


Alpha7 nicotinic acetylcholine receptor is required for amyloid pathology in brain endothelial cells induced by Glycoprotein 120, methamphetamine and nicotine.

Liu L, Yu J, Li L, Zhang B, Liu L, Wu CH, Jong A, Mao DA, Huang SH.

Sci Rep. 2017 Jan 11;7:40467. doi: 10.1038/srep40467.


Circulating brain microvascular endothelial cells (cBMECs) as potential biomarkers of the blood-brain barrier disorders caused by microbial and non-microbial factors.

Huang SH, Wang L, Chi F, Wu CH, Cao H, Zhang A, Jong A.

PLoS One. 2013 Apr 26;8(4):e62164. doi: 10.1371/journal.pone.0062164. Print 2013.


Meningitic Escherichia coli K1 penetration and neutrophil transmigration across the blood-brain barrier are modulated by alpha7 nicotinic receptor.

Chi F, Wang L, Zheng X, Wu CH, Jong A, Sheard MA, Shi W, Huang SH.

PLoS One. 2011;6(9):e25016. doi: 10.1371/journal.pone.0025016. Epub 2011 Sep 22.


Methyllycaconitine prevents methamphetamine-induced effects in mouse striatum: involvement of alpha7 nicotinic receptors.

Escubedo E, Chipana C, Pérez-Sánchez M, Camarasa J, Pubill D.

J Pharmacol Exp Ther. 2005 Nov;315(2):658-67. Epub 2005 Aug 2.


Methamphetamine alters blood brain barrier protein expression in mice, facilitating central nervous system infection by neurotropic Cryptococcus neoformans.

Eugenin EA, Greco JM, Frases S, Nosanchuk JD, Martinez LR.

J Infect Dis. 2013 Aug 15;208(4):699-704. doi: 10.1093/infdis/jit117. Epub 2013 Mar 26.


Anti-inflammatory effects of astroglial α7 nicotinic acetylcholine receptors are mediated by inhibition of the NF-κB pathway and activation of the Nrf2 pathway.

Patel H, McIntire J, Ryan S, Dunah A, Loring R.

J Neuroinflammation. 2017 Sep 26;14(1):192. doi: 10.1186/s12974-017-0967-6.


The role of the α7 subunit of the nicotinic acetylcholine receptor on motor coordination in mice treated with methyllycaconitine and anabasine.

Welch KD, Pfister JA, Gardner DR, Green BT, Panter KE.

J Appl Toxicol. 2013 Sep;33(9):1017-26. doi: 10.1002/jat.2894. Epub 2013 May 24.


Tropisetron as a neuroprotective agent against glutamate-induced excitotoxicity and mechanisms of action.

Swartz MM, Linn DM, Linn CL.

Neuropharmacology. 2013 Oct;73:111-21. doi: 10.1016/j.neuropharm.2013.05.020. Epub 2013 May 29.


HIV-1 gp41 ectodomain enhances Cryptococcus neoformans binding to human brain microvascular endothelial cells via gp41 core-induced membrane activities.

Huang SH, Wu CH, Jiang S, Bahner I, Lossinsky AS, Jong AY.

Biochem J. 2011 Sep 15;438(3):457-66. doi: 10.1042/BJ20110218.


The role of the α7 subunit of the nicotinic acetylcholine receptor in the acute toxicosis of methyllycaconitine in mice.

Welch KD, Green BT, Panter KE, Pfister JA, Gardner DR.

J Appl Toxicol. 2013 Sep;33(9):1011-6. doi: 10.1002/jat.2851. Epub 2013 Jan 8.


Biomolecular recognition of antagonists by α7 nicotinic acetylcholine receptor: Antagonistic mechanism and structure-activity relationships studies.

Peng W, Ding F.

Eur J Pharm Sci. 2015 Aug 30;76:119-32. doi: 10.1016/j.ejps.2015.05.005. Epub 2015 May 7.


A novel nicotinic mechanism underlies β-amyloid-induced neurotoxicity.

Liu Q, Xie X, Emadi S, Sierks MR, Wu J.

Neuropharmacology. 2015 Oct;97:457-63. doi: 10.1016/j.neuropharm.2015.04.025. Epub 2015 May 7.


GTS-21 attenuates lipopolysaccharide-induced inflammatory cytokine production in vitro by modulating the Akt and NF-κB signaling pathway through the α7 nicotinic acetylcholine receptor.

Yue Y, Liu R, Cheng W, Hu Y, Li J, Pan X, Peng J, Zhang P.

Int Immunopharmacol. 2015 Dec;29(2):504-512. doi: 10.1016/j.intimp.2015.10.005. Epub 2015 Oct 18.


Selective activation of α7 nicotinic acetylcholine receptor by PHA-543613 improves Aβ25-35-mediated cognitive deficits in mice.

Sadigh-Eteghad S, Talebi M, Mahmoudi J, Babri S, Shanehbandi D.

Neuroscience. 2015 Jul 9;298:81-93. doi: 10.1016/j.neuroscience.2015.04.017. Epub 2015 Apr 13.


Activation of nicotinic cholinergic receptors prevents ventilator-induced lung injury in rats.

Brégeon F, Xeridat F, Andreotti N, Lepidi H, Delpierre S, Roch A, Ravailhe S, Jammes Y, Steinberg JG.

PLoS One. 2011;6(8):e22386. doi: 10.1371/journal.pone.0022386. Epub 2011 Aug 8.


Inhibition of both alpha7* and beta2* nicotinic acetylcholine receptors is necessary to prevent development of sensitization to cocaine-elicited increases in extracellular dopamine levels in the ventral striatum.

Zanetti L, de Kerchove D'Exaerde A, Zanardi A, Changeux JP, Picciotto MR, Zoli M.

Psychopharmacology (Berl). 2006 Aug;187(2):181-8. Epub 2006 Jun 1.


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