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Items: 1 to 20 of 196

1.

Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia.

Kautz L, Jung G, Du X, Gabayan V, Chapman J, Nasoff M, Nemeth E, Ganz T.

Blood. 2015 Oct 22;126(17):2031-7. doi: 10.1182/blood-2015-07-658419. Epub 2015 Aug 14.

2.

Identification of erythroferrone as an erythroid regulator of iron metabolism.

Kautz L, Jung G, Valore EV, Rivella S, Nemeth E, Ganz T.

Nat Genet. 2014 Jul;46(7):678-84. doi: 10.1038/ng.2996. Epub 2014 Jun 1.

3.

Erythroferrone: the missing link in β-thalassemia?

Moura IC, Hermine O.

Blood. 2015 Oct 22;126(17):1974-5. doi: 10.1182/blood-2015-09-665596.

4.

Deletion of TMPRSS6 attenuates the phenotype in a mouse model of β-thalassemia.

Nai A, Pagani A, Mandelli G, Lidonnici MR, Silvestri L, Ferrari G, Camaschella C.

Blood. 2012 May 24;119(21):5021-9. doi: 10.1182/blood-2012-01-401885. Epub 2012 Apr 6.

5.

Liver expression of hepcidin and other iron genes in two mouse models of beta-thalassemia.

De Franceschi L, Daraio F, Filippini A, Carturan S, Muchitsch EM, Roetto A, Camaschella C.

Haematologica. 2006 Oct;91(10):1336-42.

6.

An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe(-/-) mice and ameliorates anemia and iron overload in murine β-thalassemia intermedia.

Schmidt PJ, Toudjarska I, Sendamarai AK, Racie T, Milstein S, Bettencourt BR, Hettinger J, Bumcrot D, Fleming MD.

Blood. 2013 Feb 14;121(7):1200-8. doi: 10.1182/blood-2012-09-453977. Epub 2012 Dec 6.

7.

mRNA expression of iron regulatory genes in beta-thalassemia intermedia and beta-thalassemia major mouse models.

Weizer-Stern O, Adamsky K, Amariglio N, Rachmilewitz E, Breda L, Rivella S, Rechavi G.

Am J Hematol. 2006 Jul;81(7):479-83.

8.

A competitive enzyme-linked immunosorbent assay specific for murine hepcidin-1: correlation with hepatic mRNA expression in established and novel models of dysregulated iron homeostasis.

Gutschow P, Schmidt PJ, Han H, Ostland V, Bartnikas TB, Pettiglio MA, Herrera C, Butler JS, Nemeth E, Ganz T, Fleming MD, Westerman M.

Haematologica. 2015 Feb;100(2):167-77. doi: 10.3324/haematol.2014.116723. Epub 2014 Nov 25.

9.

Decreasing TfR1 expression reverses anemia and hepcidin suppression in β-thalassemic mice.

Li H, Choesang T, Bao W, Chen H, Feola M, Garcia-Santos D, Li J, Sun S, Follenzi A, Pham P, Liu J, Zhang J, Ponka P, An X, Mohandas N, Fleming RE, Rivella S, Li G, Ginzburg YZ.

Blood. 2017 Mar 16;129(11):1514-1526. doi: 10.1182/blood-2016-09-742387. Epub 2017 Feb 1. Erratum in: Blood. 2017 Dec 21;130(25):2809.

10.

Erythroferrone contributes to recovery from anemia of inflammation.

Kautz L, Jung G, Nemeth E, Ganz T.

Blood. 2014 Oct 16;124(16):2569-74. doi: 10.1182/blood-2014-06-584607. Epub 2014 Sep 5.

11.

Characterization of Putative Erythroid Regulators of Hepcidin in Mouse Models of Anemia.

Mirciov CS, Wilkins SJ, Dunn LA, Anderson GJ, Frazer DM.

PLoS One. 2017 Jan 30;12(1):e0171054. doi: 10.1371/journal.pone.0171054. eCollection 2017.

12.

EPO-dependent induction of erythroferrone drives hepcidin suppression and systematic iron absorption under phenylhydrazine-induced hemolytic anemia.

Jiang X, Gao M, Chen Y, Liu J, Qi S, Ma J, Zhang Z, Xu Y.

Blood Cells Mol Dis. 2016 May;58:45-51. doi: 10.1016/j.bcmd.2016.02.005. Epub 2016 Feb 19.

PMID:
27067488
13.

Increased hepcidin in transferrin-treated thalassemic mice correlates with increased liver BMP2 expression and decreased hepatocyte ERK activation.

Chen H, Choesang T, Li H, Sun S, Pham P, Bao W, Feola M, Westerman M, Li G, Follenzi A, Blanc L, Rivella S, Fleming RE, Ginzburg YZ.

Haematologica. 2016 Mar;101(3):297-308. doi: 10.3324/haematol.2015.127902. Epub 2015 Dec 3.

14.

Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice.

Gardenghi S, Ramos P, Marongiu MF, Melchiori L, Breda L, Guy E, Muirhead K, Rao N, Roy CN, Andrews NC, Nemeth E, Follenzi A, An X, Mohandas N, Ginzburg Y, Rachmilewitz EA, Giardina PJ, Grady RW, Rivella S.

J Clin Invest. 2010 Dec;120(12):4466-77. doi: 10.1172/JCI41717. Epub 2010 Nov 22.

15.

Exogenous iron increases hemoglobin in beta-thalassemic mice.

Ginzburg YZ, Rybicki AC, Suzuka SM, Hall CB, Breuer W, Cabantchik ZI, Bouhassira EE, Fabry ME, Nagel RL.

Exp Hematol. 2009 Feb;37(2):172-83. doi: 10.1016/j.exphem.2008.10.004. Epub 2008 Dec 6.

PMID:
19059700
16.

Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin.

Gardenghi S, Marongiu MF, Ramos P, Guy E, Breda L, Chadburn A, Liu Y, Amariglio N, Rechavi G, Rachmilewitz EA, Breuer W, Cabantchik ZI, Wrighting DM, Andrews NC, de Sousa M, Giardina PJ, Grady RW, Rivella S.

Blood. 2007 Jun 1;109(11):5027-35. Epub 2007 Feb 13.

17.

Hepcidin and Hfe in iron overload in beta-thalassemia.

Gardenghi S, Ramos P, Follenzi A, Rao N, Rachmilewitz EA, Giardina PJ, Grady RW, Rivella S.

Ann N Y Acad Sci. 2010 Aug;1202:221-5. doi: 10.1111/j.1749-6632.2010.05595.x. Review.

18.

Immunoassay for human serum erythroferrone.

Ganz T, Jung G, Naeim A, Ginzburg Y, Pakbaz Z, Walter PB, Kautz L, Nemeth E.

Blood. 2017 Sep 7;130(10):1243-1246. doi: 10.1182/blood-2017-04-777987. Epub 2017 Jul 24.

19.

Hepcidin is suppressed by erythropoiesis in hemoglobin E β-thalassemia and β-thalassemia trait.

Jones E, Pasricha SR, Allen A, Evans P, Fisher CA, Wray K, Premawardhena A, Bandara D, Perera A, Webster C, Sturges P, Olivieri NF, St Pierre T, Armitage AE, Porter JB, Weatherall DJ, Drakesmith H.

Blood. 2015 Jan 29;125(5):873-80. doi: 10.1182/blood-2014-10-606491. Epub 2014 Dec 17.

20.

Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells.

Tanno T, Porayette P, Sripichai O, Noh SJ, Byrnes C, Bhupatiraju A, Lee YT, Goodnough JB, Harandi O, Ganz T, Paulson RF, Miller JL.

Blood. 2009 Jul 2;114(1):181-6. doi: 10.1182/blood-2008-12-195503. Epub 2009 May 4.

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