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IL-34 Suppresses Candida albicans Induced TNFα Production in M1 Macrophages by Downregulating Expression of Dectin-1 and TLR2.

Xu R, Sun HF, Williams DW, Jones AV, Al-Hussaini A, Song B, Wei XQ.

J Immunol Res. 2015;2015:328146. doi: 10.1155/2015/328146. Epub 2015 Jun 3.


Lipopolysaccharide-induced M2 to M1 macrophage transformation for IL-12p70 production is blocked by Candida albicans mediated up-regulation of EBI3 expression.

Zheng XF, Hong YX, Feng GJ, Zhang GF, Rogers H, Lewis MA, Williams DW, Xia ZF, Song B, Wei XQ.

PLoS One. 2013 May 27;8(5):e63967. doi: 10.1371/journal.pone.0063967. Print 2013.


Efficient capture of Candida albicans and zymosan by SIGNR1 augments TLR2-dependent TNF-α production.

Takahara K, Tokieda S, Nagaoka K, Inaba K.

Int Immunol. 2012 Feb;24(2):89-96. doi: 10.1093/intimm/dxr103. Epub 2011 Dec 29.


Vibrio cholerae porin OmpU mediates M1-polarization of macrophages/monocytes via TLR1/TLR2 activation.

Khan J, Sharma PK, Mukhopadhaya A.

Immunobiology. 2015 Nov;220(11):1199-209. doi: 10.1016/j.imbio.2015.06.009. Epub 2015 Jun 5.


Mannan-binding lectin inhibits Candida albicans-induced cellular responses in PMA-activated THP-1 cells through Toll-like receptor 2 and Toll-like receptor 4.

Wang M, Wang F, Yang J, Zhao D, Wang H, Shao F, Wang W, Sun R, Ling M, Zhai J, Song S.

PLoS One. 2013 Dec 31;8(12):e83517. doi: 10.1371/journal.pone.0083517. eCollection 2013.


Cytosolic phospholipase a2 activation by Candida albicans in alveolar macrophages: role of dectin-1.

Parti RP, Loper R, Brown GD, Gordon S, Taylor PR, Bonventre JV, Murphy RC, Williams DL, Leslie CC.

Am J Respir Cell Mol Biol. 2010 Apr;42(4):415-23. doi: 10.1165/rcmb.2009-0110OC. Epub 2009 Jun 5.


Candida albicans cell wall components and farnesol stimulate the expression of both inflammatory and regulatory cytokines in the murine RAW264.7 macrophage cell line.

Ghosh S, Howe N, Volk K, Tati S, Nickerson KW, Petro TM.

FEMS Immunol Med Microbiol. 2010 Oct;60(1):63-73. doi: 10.1111/j.1574-695X.2010.00717.x.


Candida albicans induces selective development of macrophages and monocyte derived dendritic cells by a TLR2 dependent signalling.

Yáñez A, Megías J, O'Connor JE, Gozalbo D, Gil ML.

PLoS One. 2011;6(9):e24761. doi: 10.1371/journal.pone.0024761. Epub 2011 Sep 15.


TLR2, TLR4 and Dectin-1 signalling in hematopoietic stem and progenitor cells determines the antifungal phenotype of the macrophages they produce.

Megías J, Martínez A, Yáñez A, Goodridge HS, Gozalbo D, Gil ML.

Microbes Infect. 2016 May;18(5):354-63. doi: 10.1016/j.micinf.2016.01.005. Epub 2016 Jan 29.


Proteomic characterization of human proinflammatory M1 and anti-inflammatory M2 macrophages and their response to Candida albicans.

Reales-Calderón JA, Aguilera-Montilla N, Corbí ÁL, Molero G, Gil C.

Proteomics. 2014 Jun;14(12):1503-18. doi: 10.1002/pmic.201300508. Epub 2014 May 22.


The macrophage-inducible C-type lectin, mincle, is an essential component of the innate immune response to Candida albicans.

Wells CA, Salvage-Jones JA, Li X, Hitchens K, Butcher S, Murray RZ, Beckhouse AG, Lo YL, Manzanero S, Cobbold C, Schroder K, Ma B, Orr S, Stewart L, Lebus D, Sobieszczuk P, Hume DA, Stow J, Blanchard H, Ashman RB.

J Immunol. 2008 Jun 1;180(11):7404-13.


Intestinal colonization by Candida albicans alters inflammatory responses in Bruton's tyrosine kinase-deficient mice.

Strijbis K, Yilmaz OH, Dougan SK, Esteban A, Gröne A, Kumamoto CA, Ploegh HL.

PLoS One. 2014 Nov 7;9(11):e112472. doi: 10.1371/journal.pone.0112472. eCollection 2014.


Pathways regulating cytosolic phospholipase A2 activation and eicosanoid production in macrophages by Candida albicans.

Suram S, Gangelhoff TA, Taylor PR, Rosas M, Brown GD, Bonventre JV, Akira S, Uematsu S, Williams DL, Murphy RC, Leslie CC.

J Biol Chem. 2010 Oct 1;285(40):30676-85. doi: 10.1074/jbc.M110.143800. Epub 2010 Jul 18.


PPARγ controls Dectin-1 expression required for host antifungal defense against Candida albicans.

Galès A, Conduché A, Bernad J, Lefevre L, Olagnier D, Béraud M, Martin-Blondel G, Linas MD, Auwerx J, Coste A, Pipy B.

PLoS Pathog. 2010 Jan;6(1):e1000714. doi: 10.1371/journal.ppat.1000714. Epub 2010 Jan 8.


Mast cells phagocyte Candida albicans and produce nitric oxide by mechanisms involving TLR2 and Dectin-1.

Pinke KH, Lima HG, Cunha FQ, Lara VS.

Immunobiology. 2016 Feb;221(2):220-7. doi: 10.1016/j.imbio.2015.09.004. Epub 2015 Sep 7.


Biological importance of the two Toll-like receptors, TLR2 and TLR4, in macrophage response to infection with Candida albicans.

Blasi E, Mucci A, Neglia R, Pezzini F, Colombari B, Radzioch D, Cossarizza A, Lugli E, Volpini G, Del Giudice G, Peppoloni S.

FEMS Immunol Med Microbiol. 2005 Apr 1;44(1):69-79.


Differential cytokine production and Toll-like receptor signaling pathways by Candida albicans blastoconidia and hyphae.

van der Graaf CA, Netea MG, Verschueren I, van der Meer JW, Kullberg BJ.

Infect Immun. 2005 Nov;73(11):7458-64.


Role of bacterial lipopolysaccharide in enhancing host immune response to Candida albicans.

Rogers H, Williams DW, Feng GJ, Lewis MA, Wei XQ.

Clin Dev Immunol. 2013;2013:320168. doi: 10.1155/2013/320168. Epub 2013 Jan 21.


The Role of Dectin-2 for Host Defense Against Disseminated Candidiasis.

Ifrim DC, Quintin J, Courjol F, Verschueren I, van Krieken JH, Koentgen F, Fradin C, Gow NA, Joosten LA, van der Meer JW, van de Veerdonk F, Netea MG.

J Interferon Cytokine Res. 2016 Apr;36(4):267-76. doi: 10.1089/jir.2015.0040. Epub 2016 Jan 27.

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