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Items: 1 to 20 of 147

1.

Glucocorticoid receptor gene (NR3C1) methylation processes as mediators of early adversity in stress-related disorders causality: A critical review.

Palma-Gudiel H, Córdova-Palomera A, Leza JC, Fañanás L.

Neurosci Biobehav Rev. 2015 Aug;55:520-35. doi: 10.1016/j.neubiorev.2015.05.016. Epub 2015 Jun 11. Review.

2.

Maternal psychosocial stress during pregnancy alters the epigenetic signature of the glucocorticoid receptor gene promoter in their offspring: a meta-analysis.

Palma-Gudiel H, Córdova-Palomera A, Eixarch E, Deuschle M, Fañanás L.

Epigenetics. 2015;10(10):893-902. doi: 10.1080/15592294.2015.1088630. Review.

3.

Methylation at the CpG island shore region upregulates Nr3c1 promoter activity after early-life stress.

Bockmühl Y, Patchev AV, Madejska A, Hoffmann A, Sousa JC, Sousa N, Holsboer F, Almeida OF, Spengler D.

Epigenetics. 2015;10(3):247-57. doi: 10.1080/15592294.2015.1017199.

4.

Childhood adversity and epigenetic modulation of the leukocyte glucocorticoid receptor: preliminary findings in healthy adults.

Tyrka AR, Price LH, Marsit C, Walters OC, Carpenter LL.

PLoS One. 2012;7(1):e30148. doi: 10.1371/journal.pone.0030148. Epub 2012 Jan 25.

5.

Glucocorticoid receptor gene (NR3C1) DNA methylation in association with trauma, psychopathology, transcript expression, or genotypic variation: A systematic review.

Watkeys OJ, Kremerskothen K, Quidé Y, Fullerton JM, Green MJ.

Neurosci Biobehav Rev. 2018 Dec;95:85-122. doi: 10.1016/j.neubiorev.2018.08.017. Epub 2018 Aug 31.

PMID:
30176278
6.

Glucocorticoid receptor gene methylation moderates the association of childhood trauma and cortisol stress reactivity.

Alexander N, Kirschbaum C, Wankerl M, Stauch BJ, Stalder T, Steudte-Schmiedgen S, Muehlhan M, Miller R.

Psychoneuroendocrinology. 2018 Apr;90:68-75. doi: 10.1016/j.psyneuen.2018.01.020. Epub 2018 Jan 31.

PMID:
29433075
7.

Lower methylation of glucocorticoid receptor gene promoter 1F in peripheral blood of veterans with posttraumatic stress disorder.

Yehuda R, Flory JD, Bierer LM, Henn-Haase C, Lehrner A, Desarnaud F, Makotkine I, Daskalakis NP, Marmar CR, Meaney MJ.

Biol Psychiatry. 2015 Feb 15;77(4):356-64. doi: 10.1016/j.biopsych.2014.02.006. Epub 2014 Feb 17.

PMID:
24661442
8.

Epigenetic modification of the glucocorticoid receptor gene is linked to traumatic memory and post-traumatic stress disorder risk in genocide survivors.

Vukojevic V, Kolassa IT, Fastenrath M, Gschwind L, Spalek K, Milnik A, Heck A, Vogler C, Wilker S, Demougin P, Peter F, Atucha E, Stetak A, Roozendaal B, Elbert T, Papassotiropoulos A, de Quervain DJ.

J Neurosci. 2014 Jul 30;34(31):10274-84. doi: 10.1523/JNEUROSCI.1526-14.2014.

9.

Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses.

Oberlander TF, Weinberg J, Papsdorf M, Grunau R, Misri S, Devlin AM.

Epigenetics. 2008 Mar-Apr;3(2):97-106.

PMID:
18536531
10.

NR3C1 hypermethylation in depressed and bullied adolescents.

Efstathopoulos P, Andersson F, Melas PA, Yang LL, Villaescusa JC, Rȕegg J, Ekström TJ, Forsell Y, Galanti MR, Lavebratt C.

Transl Psychiatry. 2018 Jun 19;8(1):121. doi: 10.1038/s41398-018-0169-8.

11.

Glucocorticoid receptor gene methylation and HPA-axis regulation in adolescents. The TRAILS study.

van der Knaap LJ, Oldehinkel AJ, Verhulst FC, van Oort FV, Riese H.

Psychoneuroendocrinology. 2015 Aug;58:46-50. doi: 10.1016/j.psyneuen.2015.04.012. Epub 2015 Apr 24.

PMID:
25951242
12.

Chronic Fatigue Syndrome and DNA Hypomethylation of the Glucocorticoid Receptor Gene Promoter 1F Region: Associations With HPA Axis Hypofunction and Childhood Trauma.

Vangeel E, Van Den Eede F, Hompes T, Izzi B, Del Favero J, Moorkens G, Lambrechts D, Freson K, Claes S.

Psychosom Med. 2015 Oct;77(8):853-62. doi: 10.1097/PSY.0000000000000224.

PMID:
26230484
13.

Methylation of the leukocyte glucocorticoid receptor gene promoter in adults: associations with early adversity and depressive, anxiety and substance-use disorders.

Tyrka AR, Parade SH, Welch ES, Ridout KK, Price LH, Marsit C, Philip NS, Carpenter LL.

Transl Psychiatry. 2016 Jul 5;6(7):e848. doi: 10.1038/tp.2016.112.

14.

Increased methylation at an unexplored glucocorticoid responsive element within exon 1D of NR3C1 gene is related to anxious-depressive disorders and decreased hippocampal connectivity.

Palma-Gudiel H, Córdova-Palomera A, Tornador C, Falcón C, Bargalló N, Deco G, Fañanás L.

Eur Neuropsychopharmacol. 2018 May;28(5):579-588. doi: 10.1016/j.euroneuro.2018.03.015. Epub 2018 Apr 10.

PMID:
29650294
15.

Increased methylation of glucocorticoid receptor gene (NR3C1) in adults with a history of childhood maltreatment: a link with the severity and type of trauma.

Perroud N, Paoloni-Giacobino A, Prada P, Olié E, Salzmann A, Nicastro R, Guillaume S, Mouthon D, Stouder C, Dieben K, Huguelet P, Courtet P, Malafosse A.

Transl Psychiatry. 2011 Dec 13;1:e59. doi: 10.1038/tp.2011.60.

16.

DNA methylation differences at the glucocorticoid receptor gene in depression are related to functional alterations in hypothalamic-pituitary-adrenal axis activity and to early life emotional abuse.

Farrell C, Doolin K, O' Leary N, Jairaj C, Roddy D, Tozzi L, Morris D, Harkin A, Frodl T, Nemoda Z, Szyf M, Booij L, O'Keane V.

Psychiatry Res. 2018 Jul;265:341-348. doi: 10.1016/j.psychres.2018.04.064. Epub 2018 May 8.

PMID:
29793048
17.

Tissue-, sex-, and age-specific DNA methylation of rat glucocorticoid receptor gene promoter and insulin-like growth factor 2 imprinting control region.

Agba OB, Lausser L, Huse K, Bergmeier C, Jahn N, Groth M, Bens M, Sahm A, Gall M, Witte OW, Kestler HA, Schwab M, Platzer M.

Physiol Genomics. 2017 Nov 1;49(11):690-702. doi: 10.1152/physiolgenomics.00009.2017. Epub 2017 Sep 15.

PMID:
28916632
18.

Glucocorticoid receptor gene (NR3C1) methylation following stressful events between birth and adolescence. The TRAILS study.

van der Knaap LJ, Riese H, Hudziak JJ, Verbiest MM, Verhulst FC, Oldehinkel AJ, van Oort FV.

Transl Psychiatry. 2014 Apr 8;4:e381. doi: 10.1038/tp.2014.22.

19.

Longitudinal associations between glucocorticoid receptor methylation and late-life depression.

Kang HJ, Bae KY, Kim SW, Shin IS, Kim HR, Shin MG, Yoon JS, Kim JM.

Prog Neuropsychopharmacol Biol Psychiatry. 2018 Jun 8;84(Pt A):56-62. doi: 10.1016/j.pnpbp.2018.02.004. Epub 2018 Feb 9.

PMID:
29432878
20.

Glucocorticoid receptor exon 1F methylation and the cortisol stress response in health and disease.

Schür RR, van Leeuwen JMC, Houtepen LC, Joëls M, Kahn RS, Boks MP, Vinkers CH.

Psychoneuroendocrinology. 2018 Nov;97:182-189. doi: 10.1016/j.psyneuen.2018.07.018. Epub 2018 Jul 11.

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