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26043024,25984893,21536669,32966780,26109433,29535191,26551485,28792301,27846364,21174067,22017874,20600853,27308733,27626179,25723488,22377621,26349538,26637326,31690171,21371883,34424124,35840557,16507771,29929426,29261001,28536631,26797053,33713737,26090719,28614034,23219816,32747568,27832521,25709080,32366200,23612225,29789637,27683126,23644654,23989536,32817432,34382902,24805111,19164601,25296649,25959705,29021346,24664425,25429107,19812211,26237736,20971078,24069311,30910794,35722992,23922739,31711362,25002530,26409479,31204559,24269898,20103647,20412801,28467788,29941919,31875696,24120520,29938581,30287680,28121484,30834832,20651984,25049227,30954557,23674497,32868373,27791183,21771882,20680098,25422130,28599191,28121483,24291777,28740232,19398892,35853457,28619261,32164484,35790913,17308121,27169614,31568628,27560450,17331981,22875985,22685320,25153785,27780373,30009671,36357400,27050454,25484081,26762228,26595805,24449574,24157661,22726552,26898796,16286508,26211587,30634694,24959866,25605012,29654755,28130214,35322538,24599075,22580998,26432171,29909722,23991959,20168092,17580304,29976090,19881538,23928700,30744518,17620365,22902070,30347865,26018155,27233943,20061800,34565737,31242129,26075355,32297217,28359760,28415782,27677741,22034875,27422413,31361156,24655592,27551072,35184662,30647455,27364102,22178386,28369861,20018885,29524420,29507222,31121280,32370022,27165736,31295808,32910713,23519119,24215712,33719859,30067838,24220501,31002009,28424968,24675466,24413169,29196868,29289595,32790954,24086678,27263777,35269473,28534814,22518844,29361800,27920251,22726545,21062285,36088079,30253345,17525289,24394643,17986870,31857589,19458478,19200883,27655709,26471237,24934808,31818366,24023840,29738534,29405094,21125340,24998528,34890823,27568838,26240410,20574168,33768999,35237597,25301065,33782410,27118406,31983437,30503389,24589617,28460188,25914958,30962579,21119307,26205085,27391408,22028791,31399560,28782635,21252911,30001636,35920704,32963011,27132469,23575457,23893020,30768956,27264969,26637366,18174161,31750913,35114585,23729400,23559006,27325701,27653365,30612952,28322253,29863498,34298888,19007431,24530967,26483381,23300799,30770874,27112194,28391610,21242725,34440758,28924240,32299840,23503475,27533450,16874037,29729272,26695547,25034783,19755988,33545068,36426924,22622177,34649278,25906314,28450279,34951719,31601788,30131440,27565383,29738493,26186973,34360560,33662035,32041473,27132793,28878026,25344067,28537904,26423274,25484085,32187357,24240628,33482469,34471133,31744379,27807830,30290711,34697296,24618016,26500282,32960686,33510039,36781380,35205670,25837675,29031566,26112016,30120248,23380587,26303972,24029229,26984755,25921531,32127256,30610101,19250912,36894562,25714619,36936919,19524509,33168630,21203451,31952347,24091665,27567537,27284736,27421095,34520793,30737236,25311206,30588824,27793878,29070146,29247244,30294774,18347073,27050463,27693582,31036905,21494086,18336194,36227332,29342507,31817163,26643258,25804753,25286379,15911346,25380823,28159418,32337819,26413874,28812433,29343546,32274755,33158300,20009561,32302550,29148034,33020912,24022788,35014767,33318468,24556681,28855742,21460612,28867468,28279189,23338832,26947893,36771100,31785334,26930712,35799322,25597745,33249983,24124537,36259256,25510159,28743182,36282272,30858500,31776985,22792322,25672626,17132049,36170818,26929451,29571878,26327694,24122957,28244987,31155706,31429038,21568912,34655466,20206555,32341332,26677174,32101123,30806139,30386953,21537343,25470352,36786531,25046115,32442437,29980194,28079010,28120277,33521927,35039480,29719055,33007418,34740308,35452957,24712303,35173167,30941888,34391873,36306030,35446347,31940398,24557832,23239879,24553345,23946485,25051369,30231994,27242780,26986194,33599798,26827824,29708066,32039016,26268733,29080972,16774923,28951592,30529741,29930081,28500557,23800266,30910028,36184612,24769734,35663979,29246658,26831301,27159576,30657305,23901248,34378191,28104575,27187449,25496309,34633870,21670587,29052093,33338270,33318477,25069858,32969571,29343728,31375263,21757721,29327347,20864809,28377722,23752596,27771898,35233680,25183816,25092168,31006338,30653391,31406108,32707866,28552582,22844777,21325881,26013169,22874554,31787362,33677201,31340141,26286116,33259919,21628531,32671780,31014491,19593531,36479690,36964889,24261677,35269789,27477512,27769052,26108343,25888134,28214847,25710535,32922440,32085480,37010767,30760704,32724061,30465934,32093151,25772235,36224200,22952930,26598624,30712673,25093561,27613546,27351204,26087116,21079414,36232565,29515784,29311767,36619857,27161872,28758893,22322858,20553980,29307342,36481701,37047654,30633346,35526043,23670295,36948186,28665616,28650265,22978849,24991827,34117720,29911925,34948065,25000288,24659989,29665004,27744330,23523933,22842577,32751699,28978108,36729287,32825390,30533198,30694855,34363252,29196648,27124586,35104490,26466095,27022091,28404643,28342223,33884901,35722947,29027453,33128506,30577555,35166240,35236820,21189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Year	Number of Results
2004	1
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2007	10
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2009	13
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883 results

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A plastic SQSTM1/p62-dependent autophagic reserve maintains proteostasis and determines proteasome inhibitor susceptibility in multiple myeloma cells.

Milan E, Perini T, Resnati M, Orfanelli U, Oliva L, Raimondi A, Cascio P, Bachi A, Marcatti M, Ciceri F, Cenci S. Milan E, et al. Autophagy. 2015;11(7):1161-78. doi: 10.1080/15548627.2015.1052928. Autophagy. 2015. PMID: 26043024 Free PMC article.

The GST-BHMT assay reveals a distinct mechanism underlying proteasome inhibition-induced macroautophagy in mammalian cells.

Rui YN, Xu Z, Chen Z, Zhang S. Rui YN, et al. Autophagy. 2015;11(5):812-32. doi: 10.1080/15548627.2015.1034402. Autophagy. 2015. PMID: 25984893 Free PMC article.

Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: association with sequestosome 1/p62.

Myeku N, Figueiredo-Pereira ME. Myeku N, et al. J Biol Chem. 2011 Jun 24;286(25):22426-40. doi: 10.1074/jbc.M110.149252. Epub 2011 May 2. J Biol Chem. 2011. PMID: 21536669 Free PMC article.

The Interaction of the Tumor Suppressor FAM46C with p62 and FNDC3 Proteins Integrates Protein and Secretory Homeostasis.

Fucci C, Resnati M, Riva E, Perini T, Ruggieri E, Orfanelli U, Paradiso F, Cremasco F, Raimondi A, Pasqualetto E, Nuvolone M, Rampoldi L, Cenci S, Milan E. Fucci C, et al. Cell Rep. 2020 Sep 22;32(12):108162. doi: 10.1016/j.celrep.2020.108162. Cell Rep. 2020. PMID: 32966780 Free article.

KLF4-SQSTM1/p62-associated prosurvival autophagy contributes to carfilzomib resistance in multiple myeloma models.

Riz I, Hawley TS, Hawley RG. Riz I, et al. Oncotarget. 2015 Jun 20;6(17):14814-31. doi: 10.18632/oncotarget.4530. Oncotarget. 2015. PMID: 26109433 Free PMC article.

Rapid induction of p62 and GABARAPL1 upon proteasome inhibition promotes survival before autophagy activation.

Sha Z, Schnell HM, Ruoff K, Goldberg A. Sha Z, et al. J Cell Biol. 2018 May 7;217(5):1757-1776. doi: 10.1083/jcb.201708168. Epub 2018 Mar 13. J Cell Biol. 2018. PMID: 29535191 Free PMC article.

The Proteasome Inhibitor Bortezomib Maintains Osteocyte Viability in Multiple Myeloma Patients by Reducing Both Apoptosis and Autophagy: A New Function for Proteasome Inhibitors.

Toscani D, Palumbo C, Dalla Palma B, Ferretti M, Bolzoni M, Marchica V, Sena P, Martella E, Mancini C, Ferri V, Costa F, Accardi F, Craviotto L, Aversa F, Giuliani N. Toscani D, et al. J Bone Miner Res. 2016 Apr;31(4):815-27. doi: 10.1002/jbmr.2741. Epub 2015 Dec 14. J Bone Miner Res. 2016. PMID: 26551485 Free article.

SQSTM1/p62-mediated autophagy compensates for loss of proteasome polyubiquitin recruiting capacity.

Demishtein A, Fraiberg M, Berko D, Tirosh B, Elazar Z, Navon A. Demishtein A, et al. Autophagy. 2017 Oct 3;13(10):1697-1708. doi: 10.1080/15548627.2017.1356549. Epub 2017 Aug 9. Autophagy. 2017. PMID: 28792301 Free PMC article.

HSF1 stress response pathway regulates autophagy receptor SQSTM1/p62-associated proteostasis.

Watanabe Y, Tsujimura A, Taguchi K, Tanaka M. Watanabe Y, et al. Autophagy. 2017 Jan 2;13(1):133-148. doi: 10.1080/15548627.2016.1248018. Epub 2016 Nov 15. Autophagy. 2017. PMID: 27846364 Free PMC article.

Combined treatment with bortezomib plus bafilomycin A1 enhances the cytocidal effect and induces endoplasmic reticulum stress in U266 myeloma cells: crosstalk among proteasome, autophagy-lysosome and ER stress.

Kawaguchi T, Miyazawa K, Moriya S, Ohtomo T, Che XF, Naito M, Itoh M, Tomoda A. Kawaguchi T, et al. Int J Oncol. 2011 Mar;38(3):643-54. doi: 10.3892/ijo.2010.882. Epub 2010 Dec 21. Int J Oncol. 2011. PMID: 21174067

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