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Items: 1 to 20 of 30

1.

Through a Clear Cell, Darkly: HIF2α/PLIN2-Maintained Fat Droplets Protect ccRCCs from ER Stress.

Sim J, Johnson RS.

Cancer Discov. 2015 Jun;5(6):584-5. doi: 10.1158/2159-8290.CD-15-0480.

2.

HIF2α-Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma.

Qiu B, Ackerman D, Sanchez DJ, Li B, Ochocki JD, Grazioli A, Bobrovnikova-Marjon E, Diehl JA, Keith B, Simon MC.

Cancer Discov. 2015 Jun;5(6):652-67. doi: 10.1158/2159-8290.CD-14-1507. Epub 2015 Mar 31.

3.

Re: activation of HIF2α in kidney proximal tubule cells causes abnormal glycogen deposition but not tumorigenesis.

Atala A.

J Urol. 2014 Feb;191(2):555. doi: 10.1016/j.juro.2013.10.083. Epub 2013 Oct 25. No abstract available.

PMID:
24411907
4.

Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway.

Pollard PJ, Spencer-Dene B, Shukla D, Howarth K, Nye E, El-Bahrawy M, Deheragoda M, Joannou M, McDonald S, Martin A, Igarashi P, Varsani-Brown S, Rosewell I, Poulsom R, Maxwell P, Stamp GW, Tomlinson IP.

Cancer Cell. 2007 Apr;11(4):311-9.

5.

HIF-2alpha: many cancers, one engine?

Franovic A, Lee S.

Cell Cycle. 2010 Mar 1;9(5):859-60. Epub 2010 Mar 11. No abstract available.

PMID:
20348840
6.

Englerin A induces an acute inflammatory response and reveals lipid metabolism and ER stress as targetable vulnerabilities in renal cell carcinoma.

Batova A, Altomare D, Creek KE, Naviaux RK, Wang L, Li K, Green E, Williams R, Naviaux JC, Diccianni M, Yu AL.

PLoS One. 2017 Mar 15;12(3):e0172632. doi: 10.1371/journal.pone.0172632. eCollection 2017.

7.
8.

Targeting HIF2α in Clear-Cell Renal Cell Carcinoma.

Ricketts CJ, Crooks DR, Linehan WM.

Cancer Cell. 2016 Oct 10;30(4):515-517. doi: 10.1016/j.ccell.2016.09.016.

9.
10.

A Late G1 Lipid Checkpoint That Is Dysregulated in Clear Cell Renal Carcinoma Cells.

Patel D, Salloum D, Saqcena M, Chatterjee A, Mroz V, Ohh M, Foster DA.

J Biol Chem. 2017 Jan 20;292(3):936-944. doi: 10.1074/jbc.M116.757864. Epub 2016 Dec 12.

11.

How does protein misfolding in the endoplasmic reticulum affect lipid metabolism in the liver?

Wang S, Kaufman RJ.

Curr Opin Lipidol. 2014 Apr;25(2):125-32. doi: 10.1097/MOL.0000000000000056. Review.

PMID:
24565920
12.

HIF-2alpha enhances beta-catenin/TCF-driven transcription by interacting with beta-catenin.

Choi H, Chun YS, Kim TY, Park JW.

Cancer Res. 2010 Dec 15;70(24):10101-11. doi: 10.1158/0008-5472.CAN-10-0505.

13.

The role of endoplasmic reticulum in hepatic lipid homeostasis and stress signaling.

Fu S, Watkins SM, Hotamisligil GS.

Cell Metab. 2012 May 2;15(5):623-34. doi: 10.1016/j.cmet.2012.03.007. Review.

14.

Silencing glucose-regulated protein 78 induced renal cell carcinoma cell line G1 cell-cycle arrest and resistance to conventional chemotherapy.

Lin JA, Fang SU, Su CL, Hsiao CJ, Chang CC, Lin YF, Cheng CW.

Urol Oncol. 2014 Jan;32(1):29.e1-11. doi: 10.1016/j.urolonc.2012.10.006. Epub 2013 Feb 18.

PMID:
23428538
15.

STAT3 inhibitor WP1066 as a novel therapeutic agent for renal cell carcinoma.

Horiguchi A, Asano T, Kuroda K, Sato A, Asakuma J, Ito K, Hayakawa M, Sumitomo M, Asano T.

Br J Cancer. 2010 May 25;102(11):1592-9. doi: 10.1038/sj.bjc.6605691. Epub 2010 May 11.

16.

[Histochemical characteristics of renal cell cancer].

Shliapnikov VV.

Arkh Patol. 1986;48(12):53-7. Russian.

PMID:
3566548
17.

Feedback regulators of hypoxia-inducible factors and their role in cancer biology.

Henze AT, Acker T.

Cell Cycle. 2010 Jul 15;9(14):2749-63. Epub 2010 Jul 30.

PMID:
20603601
18.

Poor prognosis and advanced clinicopathological features of clear cell renal cell carcinoma (ccRCC) are associated with cytoplasmic subcellular localisation of Hypoxia inducible factor-2α.

Kroeger N, Seligson DB, Signoretti S, Yu H, Magyar CE, Huang J, Belldegrun AS, Pantuck AJ.

Eur J Cancer. 2014 May;50(8):1531-40. doi: 10.1016/j.ejca.2014.01.031. Epub 2014 Feb 21.

PMID:
24565854
19.

Expression of hypoxia inducible factor-1α and 2α in conventional renal cell carcinoma with or without sarcomatoid differentiation.

Ku JH, Park YH, Myung JK, Moon KC, Kwak C, Kim HH.

Urol Oncol. 2011 Nov-Dec;29(6):731-7. doi: 10.1016/j.urolonc.2009.08.007. Epub 2009 Nov 13.

PMID:
19914104
20.

Differential expression of caveolin-1 in renal neoplasms.

Tamaskar I, Choueiri TK, Sercia L, Rini B, Bukowski R, Zhou M.

Cancer. 2007 Aug 15;110(4):776-82.

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