Similar articles for PMID: 25951139

Year	Number of Results
1888	1
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1

Discovery of Novel Liver-Stage Antimalarials through Quantum Similarity.

Sullivan DJ, Liu Y, Mott BT, Kaludov N, Martinov MN. Sullivan DJ, et al. PLoS One. 2015 May 7;10(5):e0125593. doi: 10.1371/journal.pone.0125593. eCollection 2015. PLoS One. 2015. PMID: 25951139 Free PMC article.

2

3,5-bis(benzylidene)-4-piperidones and related N-acyl analogs: a novel cluster of antimalarials targeting the liver stage of Plasmodium falciparum.

Das U, Singh RS, Alcorn J, Hickman MR, Sciotti RJ, Leed SE, Lee PJ, Roncal N, Dimmock JR. Das U, et al. Bioorg Med Chem. 2013 Dec 1;21(23):7250-6. doi: 10.1016/j.bmc.2013.09.065. Epub 2013 Oct 8. Bioorg Med Chem. 2013. PMID: 24139941

3

Mapping antimalarial pharmacophores as a useful tool for the rapid discovery of drugs effective in vivo: design, construction, characterization, and pharmacology of metaquine.

Dascombe MJ, Drew MG, Morris H, Wilairat P, Auparakkitanon S, Moule WA, Alizadeh-Shekalgourabi S, Evans PG, Lloyd M, Dyas AM, Carr P, Ismail FM. Dascombe MJ, et al. J Med Chem. 2005 Aug 25;48(17):5423-36. doi: 10.1021/jm0408013. J Med Chem. 2005. PMID: 16107142

4

Quinolin-4(1H)-imines are potent antiplasmodial drugs targeting the liver stage of malaria.

Rodrigues T, da Cruz FP, Lafuente-Monasterio MJ, Gonçalves D, Ressurreição AS, Sitoe AR, Bronze MR, Gut J, Schneider G, Mota MM, Rosenthal PJ, Prudêncio M, Gamo FJ, Lopes F, Moreira R. Rodrigues T, et al. J Med Chem. 2013 Jun 13;56(11):4811-5. doi: 10.1021/jm400246e. Epub 2013 May 23. J Med Chem. 2013. PMID: 23701465

5

Efficacy and pharmacokinetic evaluation of a novel anti-malarial compound (NP046) in a mouse model.

Abay ET, van der Westuizen JH, Swart KJ, Gibhard L, Lawrence N, Dambuza N, Wilhelm A, Pravin K, Wiesner L. Abay ET, et al. Malar J. 2015 Jan 6;14:8. doi: 10.1186/1475-2875-14-8. Malar J. 2015. PMID: 25563929 Free PMC article.

6

New quinoline derivatives demonstrate a promising antimalarial activity against Plasmodium falciparum in vitro and Plasmodium berghei in vivo.

Soares RR, da Silva JM, Carlos BC, da Fonseca CC, de Souza LS, Lopes FV, de Paula Dias RM, Moreira PO, Abramo C, Viana GH, de Pila Varotti F, da Silva AD, Scopel KK. Soares RR, et al. Bioorg Med Chem Lett. 2015 Jun 1;25(11):2308-13. doi: 10.1016/j.bmcl.2015.04.014. Epub 2015 Apr 11. Bioorg Med Chem Lett. 2015. PMID: 25920564

7

Targeting the erythrocytic and liver stages of malaria parasites with s-triazine-based hybrids.

Rodrigues CA, Frade RF, Albuquerque IS, Perry MJ, Gut J, Machado M, Rosenthal PJ, Prudêncio M, Afonso CA, Moreira R. Rodrigues CA, et al. ChemMedChem. 2015 May;10(5):883-90. doi: 10.1002/cmdc.201500011. Epub 2015 Mar 17. ChemMedChem. 2015. PMID: 25784585

8

Flexible 3D Cell-Based Platforms for the Discovery and Profiling of Novel Drugs Targeting Plasmodium Hepatic Infection.

Arez F, Rebelo SP, Fontinha D, Simão D, Martins TR, Machado M, Fischli C, Oeuvray C, Badolo L, Carrondo MJT, Rottmann M, Spangenberg T, Brito C, Greco B, Prudêncio M, Alves PM. Arez F, et al. ACS Infect Dis. 2019 Nov 8;5(11):1831-1842. doi: 10.1021/acsinfecdis.9b00144. Epub 2019 Sep 13. ACS Infect Dis. 2019. PMID: 31479238

9

A Novel Pyrazolopyridine with in Vivo Activity in Plasmodium berghei- and Plasmodium falciparum-Infected Mouse Models from Structure-Activity Relationship Studies around the Core of Recently Identified Antimalarial Imidazopyridazines.

Le Manach C, Paquet T, Brunschwig C, Njoroge M, Han Z, Gonzàlez Cabrera D, Bashyam S, Dhinakaran R, Taylor D, Reader J, Botha M, Churchyard A, Lauterbach S, Coetzer TL, Birkholtz LM, Meister S, Winzeler EA, Waterson D, Witty MJ, Wittlin S, Jiménez-Díaz MB, Santos Martínez M, Ferrer S, Angulo-Barturen I, Street LJ, Chibale K. Le Manach C, et al. J Med Chem. 2015 Nov 12;58(21):8713-22. doi: 10.1021/acs.jmedchem.5b01605. Epub 2015 Nov 2. J Med Chem. 2015. PMID: 26502160

10

A plant-derived morphinan as a novel lead compound active against malaria liver stages.

Carraz M, Jossang A, Franetich JF, Siau A, Ciceron L, Hannoun L, Sauerwein R, Frappier F, Rasoanaivo P, Snounou G, Mazier D. Carraz M, et al. PLoS Med. 2006 Dec;3(12):e513. doi: 10.1371/journal.pmed.0030513. PLoS Med. 2006. PMID: 17194195 Free PMC article.

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