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Items: 1 to 20 of 92

1.

Induction of immunogenic cell death by targeting RIG-I-like helicases in pancreatic cancer.

Schnurr M, Duewell P.

Oncoimmunology. 2014 Dec 13;3(9):e955687. eCollection 2014 Oct.

2.

RIG-I-like helicases induce immunogenic cell death of pancreatic cancer cells and sensitize tumors toward killing by CD8(+) T cells.

Duewell P, Steger A, Lohr H, Bourhis H, Hoelz H, Kirchleitner SV, Stieg MR, Grassmann S, Kobold S, Siveke JT, Endres S, Schnurr M.

Cell Death Differ. 2014 Dec;21(12):1825-37. doi: 10.1038/cdd.2014.96. Epub 2014 Jul 11. Erratum in: Cell Death Differ. 2014 Dec;21(12):161.

3.

Immunostimulatory RNA leads to functional reprogramming of myeloid-derived suppressor cells in pancreatic cancer.

Metzger P, Kirchleitner SV, Kluge M, Koenig LM, Hörth C, Rambuscheck CA, Böhmer D, Ahlfeld J, Kobold S, Friedel CC, Endres S, Schnurr M, Duewell P.

J Immunother Cancer. 2019 Nov 6;7(1):288. doi: 10.1186/s40425-019-0778-7.

4.

Targeted activation of melanoma differentiation-associated protein 5 (MDA5) for immunotherapy of pancreatic carcinoma.

Duewell P, Beller E, Kirchleitner SV, Adunka T, Bourhis H, Siveke J, Mayr D, Kobold S, Endres S, Schnurr M.

Oncoimmunology. 2015 Apr 14;4(10):e1029698. eCollection 2015 Oct.

5.

Therapeutic efficacy of bifunctional siRNA combining TGF-β1 silencing with RIG-I activation in pancreatic cancer.

Ellermeier J, Wei J, Duewell P, Hoves S, Stieg MR, Adunka T, Noerenberg D, Anders HJ, Mayr D, Poeck H, Hartmann G, Endres S, Schnurr M.

Cancer Res. 2013 Mar 15;73(6):1709-20. doi: 10.1158/0008-5472.CAN-11-3850. Epub 2013 Jan 21.

6.

TLR4 signaling induces retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5 in mesangial cells.

Imaizumi T, Aizawa-Yashiro T, Watanabe S, Matsumiya T, Yoshida H, Tatsuta T, Xing F, Meng P, Hayakari R, Tsuruga K, Tanaka H.

J Nephrol. 2013 Sep-Oct;26(5):886-93. doi: 10.5301/jn.5000254. Epub 2013 Apr 5.

PMID:
23559071
7.

Regulation and function of the cytosolic viral RNA sensor RIG-I in pancreatic beta cells.

García M, Dogusan Z, Moore F, Sato S, Hartmann G, Eizirik DL, Rasschaert J.

Biochim Biophys Acta. 2009 Nov;1793(11):1768-75. doi: 10.1016/j.bbamcr.2009.09.005. Epub 2009 Sep 10.

8.

Mechanisms and pathways of innate immune activation and regulation in health and cancer.

Cui J, Chen Y, Wang HY, Wang RF.

Hum Vaccin Immunother. 2014;10(11):3270-85. doi: 10.4161/21645515.2014.979640. Review.

9.

Reprint of Neutrophil cell surface receptors and their intracellular signal transduction pathways.

Futosi K, Fodor S, Mócsai A.

Int Immunopharmacol. 2013 Dec;17(4):1185-97. doi: 10.1016/j.intimp.2013.11.010. Epub 2013 Nov 18. Review.

PMID:
24263067
10.

Viral RNA induces type I interferon-dependent cytokine release and cell death in mesangial cells via melanoma-differentiation-associated gene-5: Implications for viral infection-associated glomerulonephritis.

Flür K, Allam R, Zecher D, Kulkarni OP, Lichtnekert J, Schwarz M, Beutler B, Vielhauer V, Anders HJ.

Am J Pathol. 2009 Nov;175(5):2014-22. doi: 10.2353/ajpath.2009.080585. Epub 2009 Oct 22.

11.

MDA5 and ISG56 mediate CXCL10 expression induced by toll-like receptor 4 activation in U373MG human astrocytoma cells.

Imaizumi T, Murakami K, Ohta K, Seki H, Matsumiya T, Meng P, Hayakari R, Xing F, Aizawa-Yashiro T, Tatsuta T, Yoshida H, Kijima H.

Neurosci Res. 2013 Aug;76(4):195-206. doi: 10.1016/j.neures.2013.05.002. Epub 2013 May 15.

PMID:
23684765
12.

MAVS-dependent IRF3/7 bypass of interferon β-induction restricts the response to measles infection in CD150Tg mouse bone marrow-derived dendritic cells.

Takaki H, Honda K, Atarashi K, Kobayashi F, Ebihara T, Oshiumi H, Matsumoto M, Shingai M, Seya T.

Mol Immunol. 2014 Feb;57(2):100-10. doi: 10.1016/j.molimm.2013.08.007. Epub 2013 Oct 4.

13.

Particulate formulations for the delivery of poly(I:C) as vaccine adjuvant.

Hafner AM, Corthésy B, Merkle HP.

Adv Drug Deliv Rev. 2013 Oct;65(10):1386-99. doi: 10.1016/j.addr.2013.05.013. Epub 2013 Jun 7. Review.

PMID:
23751781
14.

Concomitant TLR/RLH signaling of radioresistant and radiosensitive cells is essential for protection against vesicular stomatitis virus infection.

Spanier J, Lienenklaus S, Paijo J, Kessler A, Borst K, Heindorf S, Baker DP, Kröger A, Weiss S, Detje CN, Staeheli P, Kalinke U.

J Immunol. 2014 Sep 15;193(6):3045-54. doi: 10.4049/jimmunol.1400959. Epub 2014 Aug 15.

15.

TRIM13 is a negative regulator of MDA5-mediated type I interferon production.

Narayan K, Waggoner L, Pham ST, Hendricks GL, Waggoner SN, Conlon J, Wang JP, Fitzgerald KA, Kang J.

J Virol. 2014 Sep;88(18):10748-57. doi: 10.1128/JVI.02593-13. Epub 2014 Jul 9.

16.

Molecular basis for ebolavirus VP35 suppression of human dendritic cell maturation.

Yen B, Mulder LC, Martinez O, Basler CF.

J Virol. 2014 Nov;88(21):12500-10. doi: 10.1128/JVI.02163-14. Epub 2014 Aug 20.

17.

Both RIG-I and MDA5 RNA helicases contribute to the induction of alpha/beta interferon in measles virus-infected human cells.

Ikegame S, Takeda M, Ohno S, Nakatsu Y, Nakanishi Y, Yanagi Y.

J Virol. 2010 Jan;84(1):372-9. doi: 10.1128/JVI.01690-09.

18.

An optimized retinoic acid-inducible gene I agonist M8 induces immunogenic cell death markers in human cancer cells and dendritic cell activation.

Castiello L, Zevini A, Vulpis E, Muscolini M, Ferrari M, Palermo E, Peruzzi G, Krapp C, Jakobsen M, Olagnier D, Zingoni A, Santoni A, Hiscott J.

Cancer Immunol Immunother. 2019 Sep;68(9):1479-1492. doi: 10.1007/s00262-019-02380-2. Epub 2019 Aug 28.

PMID:
31463653
19.

Sensing and control of bluetongue virus infection in epithelial cells via RIG-I and MDA5 helicases.

Chauveau E, Doceul V, Lara E, Adam M, Breard E, Sailleau C, Viarouge C, Desprat A, Meyer G, Schwartz-Cornil I, Ruscanu S, Charley B, Zientara S, Vitour D.

J Virol. 2012 Nov;86(21):11789-99. doi: 10.1128/JVI.00430-12. Epub 2012 Aug 22.

20.

Interaction between interferon-stimulated gene 56 and melanoma differentiation-associated gene 5 in Toll-like receptor 3 signaling in normal human mesangial cells.

Imaizumi T, Aizawa-Yashiro T, Matsumiya T, Yoshida H, Watanabe S, Tsuruga K, Tatsuta T, Xing F, Hayakari R, Meng P, Tanaka H.

Am J Nephrol. 2013;37(2):118-25. doi: 10.1159/000346415. Epub 2013 Jan 29.

PMID:
23363937

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