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Items: 1 to 20 of 373

1.

Identification of Cholesterol 25-Hydroxylase as a Novel Host Restriction Factor and a Part of the Primary Innate Immune Responses against Hepatitis C Virus Infection.

Xiang Y, Tang JJ, Tao W, Cao X, Song BL, Zhong J.

J Virol. 2015 Jul;89(13):6805-16. doi: 10.1128/JVI.00587-15. Epub 2015 Apr 22.

2.

Interferon-inducible cholesterol-25-hydroxylase inhibits hepatitis C virus replication via distinct mechanisms.

Chen Y, Wang S, Yi Z, Tian H, Aliyari R, Li Y, Chen G, Liu P, Zhong J, Chen X, Du P, Su L, Qin FX, Deng H, Cheng G.

Sci Rep. 2014 Dec 3;4:7242. doi: 10.1038/srep07242.

3.

Interferon-inducible cholesterol-25-hydroxylase restricts hepatitis C virus replication through blockage of membranous web formation.

Anggakusuma, Romero-Brey I, Berger C, Colpitts CC, Boldanova T, Engelmann M, Todt D, Perin PM, Behrendt P, Vondran FW, Xu S, Goffinet C, Schang LM, Heim MH, Bartenschlager R, Pietschmann T, Steinmann E.

Hepatology. 2015 Sep;62(3):702-14. doi: 10.1002/hep.27913. Epub 2015 Jul 28.

PMID:
25999047
4.

25-Hydroxycholesterol Production by the Cholesterol-25-Hydroxylase Interferon-Stimulated Gene Restricts Mammalian Reovirus Infection.

Doms A, Sanabria T, Hansen JN, Altan-Bonnet N, Holm GH.

J Virol. 2018 Aug 29;92(18). pii: e01047-18. doi: 10.1128/JVI.01047-18. Print 2018 Sep 15.

PMID:
29950420
5.

DDX60L Is an Interferon-Stimulated Gene Product Restricting Hepatitis C Virus Replication in Cell Culture.

Grünvogel O, Esser-Nobis K, Reustle A, Schult P, Müller B, Metz P, Trippler M, Windisch MP, Frese M, Binder M, Fackler O, Bartenschlager R, Ruggieri A, Lohmann V.

J Virol. 2015 Oct;89(20):10548-68. doi: 10.1128/JVI.01297-15. Epub 2015 Aug 12.

6.

EFTUD2 Is a Novel Innate Immune Regulator Restricting Hepatitis C Virus Infection through the RIG-I/MDA5 Pathway.

Zhu C, Xiao F, Hong J, Wang K, Liu X, Cai D, Fusco DN, Zhao L, Jeong SW, Brisac C, Chusri P, Schaefer EA, Zhao H, Peng LF, Lin W, Chung RT.

J Virol. 2015 Jul;89(13):6608-18. doi: 10.1128/JVI.00364-15. Epub 2015 Apr 15.

7.

Cholesterol 25-hydroxylase acts as a host restriction factor on pseudorabies virus replication.

Wang J, Zeng L, Zhang L, Guo ZZ, Lu SF, Ming SL, Li GL, Wan B, Tian KG, Yang GY, Chu BB.

J Gen Virol. 2017 Jun;98(6):1467-1476. doi: 10.1099/jgv.0.000797. Epub 2017 Jun 20.

PMID:
28631596
8.

Cholesterol 25-Hydroxylase Inhibits Porcine Reproductive and Respiratory Syndrome Virus Replication through Enzyme Activity-Dependent and -Independent Mechanisms.

Ke W, Fang L, Jing H, Tao R, Wang T, Li Y, Long S, Wang D, Xiao S.

J Virol. 2017 Sep 12;91(19). pii: e00827-17. doi: 10.1128/JVI.00827-17. Print 2017 Oct 1.

9.

25-Hydroxycholesterol Inhibition of Lassa Virus Infection through Aberrant GP1 Glycosylation.

Shrivastava-Ranjan P, Bergeron É, Chakrabarti AK, Albariño CG, Flint M, Nichol ST, Spiropoulou CF.

MBio. 2016 Dec 20;7(6). pii: e01808-16. doi: 10.1128/mBio.01808-16.

10.

Cholesterol 25-hydroxylase is an interferon-inducible factor that protects against porcine reproductive and respiratory syndrome virus infection.

Song Z, Zhang Q, Liu X, Bai J, Zhao Y, Wang X, Jiang P.

Vet Microbiol. 2017 Oct;210:153-161. doi: 10.1016/j.vetmic.2017.09.011. Epub 2017 Sep 20.

PMID:
29103685
11.

MicroRNA-130a inhibits HCV replication by restoring the innate immune response.

Li S, Duan X, Li Y, Liu B, McGilvray I, Chen L.

J Viral Hepat. 2014 Feb;21(2):121-8. doi: 10.1111/jvh.12131. Epub 2013 Jul 30.

PMID:
24383925
12.

Interferon-independent antiviral activity of 25-hydroxycholesterol in a teleost fish.

Pereiro P, Forn-Cuní G, Dios S, Coll J, Figueras A, Novoa B.

Antiviral Res. 2017 Sep;145:146-159. doi: 10.1016/j.antiviral.2017.08.003. Epub 2017 Aug 5.

PMID:
28789986
13.

Hepatitis C virus triggers apoptosis of a newly developed hepatoma cell line through antiviral defense system.

Zhu H, Dong H, Eksioglu E, Hemming A, Cao M, Crawford JM, Nelson DR, Liu C.

Gastroenterology. 2007 Nov;133(5):1649-59. Epub 2007 Sep 16.

PMID:
17983809
14.

Pathogen-Associated Molecular Pattern Recognition of Hepatitis C Virus Transmitted/Founder Variants by RIG-I Is Dependent on U-Core Length.

Kell A, Stoddard M, Li H, Marcotrigiano J, Shaw GM, Gale M Jr.

J Virol. 2015 Nov;89(21):11056-68. doi: 10.1128/JVI.01964-15. Epub 2015 Aug 26.

15.

N-Myc Downstream-Regulated Gene 1 Restricts Hepatitis C Virus Propagation by Regulating Lipid Droplet Biogenesis and Viral Assembly.

Schweitzer CJ, Zhang F, Boyer A, Valdez K, Cam M, Liang TJ.

J Virol. 2018 Jan 2;92(2). pii: e01166-17. doi: 10.1128/JVI.01166-17. Print 2018 Jan 15.

16.

HBV Bypasses the Innate Immune Response and Does Not Protect HCV From Antiviral Activity of Interferon.

Mutz P, Metz P, Lempp FA, Bender S, Qu B, Schöneweis K, Seitz S, Tu T, Restuccia A, Frankish J, Dächert C, Schusser B, Koschny R, Polychronidis G, Schemmer P, Hoffmann K, Baumert TF, Binder M, Urban S, Bartenschlager R.

Gastroenterology. 2018 May;154(6):1791-1804.e22. doi: 10.1053/j.gastro.2018.01.044. Epub 2018 Feb 1.

17.

Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol.

Liu SY, Aliyari R, Chikere K, Li G, Marsden MD, Smith JK, Pernet O, Guo H, Nusbaum R, Zack JA, Freiberg AN, Su L, Lee B, Cheng G.

Immunity. 2013 Jan 24;38(1):92-105. doi: 10.1016/j.immuni.2012.11.005. Epub 2012 Dec 27.

18.

Up-regulation of the ATP-binding cassette transporter A1 inhibits hepatitis C virus infection.

Bocchetta S, Maillard P, Yamamoto M, Gondeau C, Douam F, Lebreton S, Lagaye S, Pol S, Helle F, Plengpanich W, Guérin M, Bourgine M, Michel ML, Lavillette D, Roingeard P, le Goff W, Budkowska A.

PLoS One. 2014 Mar 19;9(3):e92140. doi: 10.1371/journal.pone.0092140. eCollection 2014.

19.

Targeting cellular squalene synthase, an enzyme essential for cholesterol biosynthesis, is a potential antiviral strategy against hepatitis C virus.

Saito K, Shirasago Y, Suzuki T, Aizaki H, Hanada K, Wakita T, Nishijima M, Fukasawa M.

J Virol. 2015 Feb;89(4):2220-32. doi: 10.1128/JVI.03385-14. Epub 2014 Dec 3.

20.

Hepatitis C virus replication in mouse cells is restricted by IFN-dependent and -independent mechanisms.

Nandakumar R, Finsterbusch K, Lipps C, Neumann B, Grashoff M, Nair S, Hochnadel I, Lienenklaus S, Wappler I, Steinmann E, Hauser H, Pietschmann T, Kröger A.

Gastroenterology. 2013 Dec;145(6):1414-23.e1. doi: 10.1053/j.gastro.2013.08.037. Epub 2013 Aug 21.

PMID:
23973921

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