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Items: 1 to 20 of 561

1.

EFTUD2 Is a Novel Innate Immune Regulator Restricting Hepatitis C Virus Infection through the RIG-I/MDA5 Pathway.

Zhu C, Xiao F, Hong J, Wang K, Liu X, Cai D, Fusco DN, Zhao L, Jeong SW, Brisac C, Chusri P, Schaefer EA, Zhao H, Peng LF, Lin W, Chung RT.

J Virol. 2015 Jul;89(13):6608-18. doi: 10.1128/JVI.00364-15. Epub 2015 Apr 15.

2.

EFTUD2 on innate immunity.

Zhu C, Xiao F, Lin W.

Oncotarget. 2015 Oct 20;6(32):32313-4. doi: 10.18632/oncotarget.5863. No abstract available.

3.

DDX60L Is an Interferon-Stimulated Gene Product Restricting Hepatitis C Virus Replication in Cell Culture.

Grünvogel O, Esser-Nobis K, Reustle A, Schult P, Müller B, Metz P, Trippler M, Windisch MP, Frese M, Binder M, Fackler O, Bartenschlager R, Ruggieri A, Lohmann V.

J Virol. 2015 Oct;89(20):10548-68. doi: 10.1128/JVI.01297-15. Epub 2015 Aug 12.

4.

MDA5 plays a critical role in interferon response during hepatitis C virus infection.

Cao X, Ding Q, Lu J, Tao W, Huang B, Zhao Y, Niu J, Liu YJ, Zhong J.

J Hepatol. 2015 Apr;62(4):771-8. doi: 10.1016/j.jhep.2014.11.007. Epub 2014 Nov 21.

PMID:
25463548
5.

Retinoic acid inducible gene-I (RIG-I) signaling of hepatic stellate cells inhibits hepatitis C virus replication in hepatocytes.

Wang Y, Ye L, Wang X, Li J, Song L, Ho W.

Innate Immun. 2013;19(2):193-202. doi: 10.1177/1753425912460414. Epub 2012 Oct 11.

6.

Pathogen-Associated Molecular Pattern Recognition of Hepatitis C Virus Transmitted/Founder Variants by RIG-I Is Dependent on U-Core Length.

Kell A, Stoddard M, Li H, Marcotrigiano J, Shaw GM, Gale M Jr.

J Virol. 2015 Nov;89(21):11056-68. doi: 10.1128/JVI.01964-15. Epub 2015 Aug 26.

7.

Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells.

Plumlee CR, Lazaro CA, Fausto N, Polyak SJ.

Virol J. 2005 Dec 2;2:89.

8.

Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2.

Saito T, Hirai R, Loo YM, Owen D, Johnson CL, Sinha SC, Akira S, Fujita T, Gale M Jr.

Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):582-7. Epub 2006 Dec 26.

9.

Establishment and maintenance of the innate antiviral response to West Nile Virus involves both RIG-I and MDA5 signaling through IPS-1.

Fredericksen BL, Keller BC, Fornek J, Katze MG, Gale M Jr.

J Virol. 2008 Jan;82(2):609-16. Epub 2007 Oct 31.

10.

Hepatitis C virus reveals a novel early control in acute immune response.

Arnaud N, Dabo S, Akazawa D, Fukasawa M, Shinkai-Ouchi F, Hugon J, Wakita T, Meurs EF.

PLoS Pathog. 2011 Oct;7(10):e1002289. doi: 10.1371/journal.ppat.1002289. Epub 2011 Oct 13.

11.

HepG2 cells mount an effective antiviral interferon-lambda based innate immune response to hepatitis C virus infection.

Israelow B, Narbus CM, Sourisseau M, Evans MJ.

Hepatology. 2014 Oct;60(4):1170-9. doi: 10.1002/hep.27227. Epub 2014 Aug 21.

12.

Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B.

Kitai Y, Takeuchi O, Kawasaki T, Ori D, Sueyoshi T, Murase M, Akira S, Kawai T.

J Biol Chem. 2015 Jan 9;290(2):1269-80. doi: 10.1074/jbc.M114.611053. Epub 2014 Dec 1.

13.

Enterovirus 2Apro targets MDA5 and MAVS in infected cells.

Feng Q, Langereis MA, Lork M, Nguyen M, Hato SV, Lanke K, Emdad L, Bhoopathi P, Fisher PB, Lloyd RE, van Kuppeveld FJ.

J Virol. 2014 Mar;88(6):3369-78. doi: 10.1128/JVI.02712-13. Epub 2014 Jan 3.

14.

The protein kinase IKKepsilon can inhibit HCV expression independently of IFN and its own expression is downregulated in HCV-infected livers.

Vilasco M, Larrea E, Vitour D, Dabo S, Breiman A, Regnault B, Riezu JI, Eid P, Prieto J, Meurs EF.

Hepatology. 2006 Dec;44(6):1635-47.

PMID:
17133498
15.

RAVER1 is a coactivator of MDA5-mediated cellular antiviral response.

Chen H, Li Y, Zhang J, Ran Y, Wei J, Yang Y, Shu HB.

J Mol Cell Biol. 2013 Apr;5(2):111-9. doi: 10.1093/jmcb/mjt006. Epub 2013 Feb 5.

PMID:
23390309
16.

Independent, parallel pathways to CXCL10 induction in HCV-infected hepatocytes.

Brownell J, Wagoner J, Lovelace ES, Thirstrup D, Mohar I, Smith W, Giugliano S, Li K, Crispe IN, Rosen HR, Polyak SJ.

J Hepatol. 2013 Oct;59(4):701-8. doi: 10.1016/j.jhep.2013.06.001. Epub 2013 Jun 12.

17.

Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA.

Saito T, Owen DM, Jiang F, Marcotrigiano J, Gale M Jr.

Nature. 2008 Jul 24;454(7203):523-7. doi: 10.1038/nature07106. Epub 2008 Jun 11.

18.

RIG-I is a key antiviral interferon-stimulated gene against hepatitis E virus regardless of interferon production.

Xu L, Wang W, Li Y, Zhou X, Yin Y, Wang Y, de Man RA, van der Laan LJW, Huang F, Kamar N, Peppelenbosch MP, Pan Q.

Hepatology. 2017 Jun;65(6):1823-1839. doi: 10.1002/hep.29105. Epub 2017 May 3.

PMID:
28195391
19.

Sustained activation of interferon regulatory factor 3 during infection by paramyxoviruses requires MDA5.

Grandvaux N, Guan X, Yoboua F, Zucchini N, Fink K, Doyon P, Martin L, Servant MJ, Chartier S.

J Innate Immun. 2014;6(5):650-62. doi: 10.1159/000360764. Epub 2014 Apr 30.

20.

Melanoma differentiation-associated gene 5 senses hepatitis B virus and activates innate immune signaling to suppress virus replication.

Lu HL, Liao F.

J Immunol. 2013 Sep 15;191(6):3264-76. doi: 10.4049/jimmunol.1300512. Epub 2013 Aug 7.

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