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25760758,29631686,23181522,23681764,28134973,24845100,24334103,25283330,22471389,23936120,28946872,29373533,23419397,23166699,25724338,28555033,21327327,27318173,26242624,29021504,26365347,30176712,32920140,21902673,30551441,24450392,22224971,24582594,26088335,24597820,23727383,25523390,27350007,27475717,25529897,26190448,23557604,26046125,27792464,23627464,23126661,25181477,24666293,33152931,23541989,26119076,29410516,29966981,24091917,26905195,25128422,23369342,27940057,21147366,26205968,22292054,30185113,27246736,27470278,29695233,20332066,25142414,25585626,24530909,23179316,25761066,19885945,25366162,24952133,29604586,26085110,28508719,16368784,31486092,29710033,35807476,30354116,28604636,29170122,27590487,21291493,21294077,19403287,22848028,22901559,27917887,26907332,28595985,27085773,24014306,24673832,27063434,22818712,29630878,29596447,23291758,25559859,20346961,17646392,26860768,26350746,28417922,24369814,31108834,23517912,20208359,26305241,20962015,22687396,30539499,29976086,17129589,26679488,16579723,18703634,27117918,24634340,17904778,26535679,23521110,26211472,26631505,19427183,21669278,25569623,23465614,22641065,25987215,26990658,25516096,27309406,27542074,26174858,25936595,32191574,19606518,26719859,25914364,27882370,30055130,18174026,34302803,26016552,32466183,26902408,29441719,30472463,28204815,25623997,22687402,32824545,26471469,28571740,29316805,26424016,21082272,22000441,27667512,17028188,14688407,32779962,22537056,15664998,28088385,23810795,28953247,24325571,26341132,20627112,29689351,15367685,16461467,26833256,17433253,25212747,25735898,19126543,24128855,29480572,31726767,28887923,28842339,28282409,28921681,27481193,14499025,21091246,27977180,20460753,17549051,26494490,28579594,28891956,28625492,30249030,19213344,28870006,11456275,23999723,26524639,33275195,21848503,27044015,26068433,30248417,26966068,15985551,29899319,26390196,28239754,26214491,26159900,28332893,29987205,25639984,27469197,29680740,35671635,23576576,19808909,28646352,23919458,31963184,19666473,25222709,27470336,17884939,19811452,32106371,24194944,34932954,26313919,30031040,28257978,25940979,29789508,30360145,34356649,25896661,28067305,29649628,25428599,29442012,27098252,28972158,30322210,24068707,27206252,36071319,17071615,18981473,19324970,24663213,28279068,26942597,29094436,29283422,21147878,25173565,24811171,28582464,20357182,28884178,26449462,34323694,27070585,21327521,17581254,12095417,26703207,30439703,25595190,29071567,30462381,33557339,34948427,32960468,22870818,27653985,23512806,21434777,29663555,22282047,18596209,33799634,9822687,20567236,20590410,28869898,25779645,17576771,32443487,30177649,26797605,18029481,26816335,31883537,20158974,20427709,28351837,32990471,11911853,29225318,33945810,33121932,19056650,26408789,34619292,26244589,27604997,30446312,31659183,26083118,23071089,31615896,24211593,24884680,29164883,25817070,28285642,32150331,19520133,30860936,22137902,27512010,26947594,26075699,30090014,26396188,31752244,23389992,30597201,28501567,25878062,34767806,36628832,27374289,26797706,32326254,22911724,29209111,15659569,19360322,21845103,12437985,26525853,27475846,23494817,23399665,28775290,15504954,29709906,33023055,21978785,21542777,29115433,28755519,25451943,25756947,30621146,24821545,22024497,33615467,26880616,19141617,22889231,24418043,31238218,30496566,28972997,28441735,23027678,32481686,15632071,28398659,26604105,31150363,31067509,29258500,35663445,27424923,31955908,28708070,19735186,35921899,28056918,18790715,27098798,12351639,22678810,22687475,22544347,23330002,28515350,15564676,28060835,29884167,21760932,28552586,23239344,27825360,23850470,31608255,26359088,31569605,25273391,17056071,22473998,26271306,24859974,23762131,20339310,28490236,23880330,32434447,35163941,26459774,26584287,36448374,22292086,21332398,28647365,20459638,27765349,29576843,31783835,18840928,31306686,35563118,27109161,11527376,29768199,23344050,25923408,26940012,31068163,31371025,30833079,18469497,21557215,19167359,29029793,24829131,32183002,28965824,27293199,23956107,23951196,25813581,21029370,22978376,29501496,19610030,22893262,20886176,24687644,31902039,20412023,23707571,28278164,23313487,24682657,29934339,26968895,26721419,29526086,32787498,20179325,35688794,14505802,24096869,30029534,30902099,32365527,25905670,19026986,28586165,27494072,17335118,21562223,29396442,31791580,27347916,31100494,21602272,29233982,34948240,34009022,21816900,34342323,27575855,22298784,23620165,28747725,32115509,29468504,15630282,36633126,23332504,25310765,25410008,26065429,20519739,23798556,27320865,28393240,34801515,30521605,31731552,34009020,30891787,28146410,26901177,34356676,30267661,36083402,25323802,31109074,19646953,15754337,31878261,31452707,21861722,25487878,35696246,28642037,31434544,27302893,35367764,18844326,31838799,18664595,31759991,27583359,26553151,23063366,29202451,20823583,19067171,27868125,15553830,16107706,28601955,24180341,27669202,26285147,31991567,29030964,29447191,32236964,35348231,30193323,26812237,29880530,24959884,281023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Zanthoxylum schinifolium leaf ethanol extract inhibits adipocyte differentiation through inactivation of the extracellular signal regulated kinase and phosphoinositide 3-kinase/Akt signaling pathways in 3T3-L1 pre-adipocytes.

Choi EO, Park C, Shin SS, Cho EJ, Kim BW, Hwang JA, Hwang HJ, Choi YH. Choi EO, et al. Mol Med Rep. 2015 Jul;12(1):1314-20. doi: 10.3892/mmr.2015.3463. Epub 2015 Mar 10. Mol Med Rep. 2015. PMID: 25760758

Anti-obesity effects of Laminaria japonica fermentation on 3T3-L1 adipocytes are mediated by the inhibition of C/EBP-α/β and PPAR-γ.

Kim YM, Jang MS. Kim YM, et al. Cell Mol Biol (Noisy-le-grand). 2018 Mar 31;64(4):71-77. Cell Mol Biol (Noisy-le-grand). 2018. PMID: 29631686

Centipede grass exerts anti-adipogenic activity through inhibition of C/EBPβ, C/EBPα, and PPARγ expression and the AKT signaling pathway in 3T3-L1 adipocytes.

Park HJ, Chung BY, Lee MK, Song Y, Lee SS, Chu GM, Kang SN, Song YM, Kim GS, Cho JH. Park HJ, et al. BMC Complement Altern Med. 2012 Nov 26;12:230. doi: 10.1186/1472-6882-12-230. BMC Complement Altern Med. 2012. PMID: 23181522 Free PMC article.

4-Hydroxyderricin and xanthoangelol from Ashitaba (Angelica keiskei) suppress differentiation of preadiopocytes to adipocytes via AMPK and MAPK pathways.

Zhang T, Sawada K, Yamamoto N, Ashida H. Zhang T, et al. Mol Nutr Food Res. 2013 Oct;57(10):1729-40. doi: 10.1002/mnfr.201300020. Epub 2013 May 16. Mol Nutr Food Res. 2013. PMID: 23681764

Fucosterol, isolated from Ecklonia stolonifera, inhibits adipogenesis through modulation of FoxO1 pathway in 3T3-L1 adipocytes.

Lee JH, Jung HA, Kang MJ, Choi JS, Kim GD. Lee JH, et al. J Pharm Pharmacol. 2017 Mar;69(3):325-333. doi: 10.1111/jphp.12684. Epub 2017 Jan 30. J Pharm Pharmacol. 2017. PMID: 28134973

The chalcones cardamonin and flavokawain B inhibit the differentiation of preadipocytes to adipocytes by activating ERK.

Zhang T, Yamamoto N, Yamashita Y, Ashida H. Zhang T, et al. Arch Biochem Biophys. 2014 Jul 15;554:44-54. doi: 10.1016/j.abb.2014.05.008. Epub 2014 May 17. Arch Biochem Biophys. 2014. PMID: 24845100

Phlorotannins isolated from the edible brown alga Ecklonia stolonifera exert anti-adipogenic activity on 3T3-L1 adipocytes by downregulating C/EBPα and PPARγ.

Jung HA, Jung HJ, Jeong HY, Kwon HJ, Ali MY, Choi JS. Jung HA, et al. Fitoterapia. 2014 Jan;92:260-9. doi: 10.1016/j.fitote.2013.12.003. Epub 2013 Dec 12. Fitoterapia. 2014. PMID: 24334103

Phloretin promotes adipocyte differentiation in vitro and improves glucose homeostasis in vivo.

Shu G, Lu NS, Zhu XT, Xu Y, Du MQ, Xie QP, Zhu CJ, Xu Q, Wang SB, Wang LN, Gao P, Xi QY, Zhang YL, Jiang QY. Shu G, et al. J Nutr Biochem. 2014 Dec;25(12):1296-308. doi: 10.1016/j.jnutbio.2014.07.007. Epub 2014 Sep 16. J Nutr Biochem. 2014. PMID: 25283330

Citrus aurantium flavonoids inhibit adipogenesis through the Akt signaling pathway in 3T3-L1 cells.

Kim GS, Park HJ, Woo JH, Kim MK, Koh PO, Min W, Ko YG, Kim CH, Won CK, Cho JH. Kim GS, et al. BMC Complement Altern Med. 2012 Apr 3;12:31. doi: 10.1186/1472-6882-12-31. BMC Complement Altern Med. 2012. PMID: 22471389 Free PMC article.

Blueberry peel extracts inhibit adipogenesis in 3T3-L1 cells and reduce high-fat diet-induced obesity.

Song Y, Park HJ, Kang SN, Jang SH, Lee SJ, Ko YG, Kim GS, Cho JH. Song Y, et al. PLoS One. 2013 Jul 25;8(7):e69925. doi: 10.1371/journal.pone.0069925. Print 2013. PLoS One. 2013. PMID: 23936120 Free PMC article.

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