Similar articles for PMID: 25741791

Year	Number of Results
1999	4
2000	1
2001	2
2002	4
2003	4
2004	4
2005	3
2006	5
2007	9
2008	3
2009	11
2010	10
2011	16
2012	23
2013	20
2014	29
2015	26
2016	30
2017	34
2018	29
2019	18
2020	18
2021	20
2022	9
2023	2
2024	0

1

The emerging role of the first 17 amino acids of huntingtin in Huntington's disease.

Arndt JR, Chaibva M, Legleiter J. Arndt JR, et al. Biomol Concepts. 2015 Mar;6(1):33-46. doi: 10.1515/bmc-2015-0001. Biomol Concepts. 2015. PMID: 25741791 Free PMC article. Review.

2

The interaction of polyglutamine peptides with lipid membranes is regulated by flanking sequences associated with huntingtin.

Burke KA, Kauffman KJ, Umbaugh CS, Frey SL, Legleiter J. Burke KA, et al. J Biol Chem. 2013 May 24;288(21):14993-5005. doi: 10.1074/jbc.M112.446237. Epub 2013 Apr 9. J Biol Chem. 2013. PMID: 23572526 Free PMC article.

3

SUMOylation Prevents Huntingtin Fibrillization and Localization onto Lipid Membranes.

Sedighi F, Adegbuyiro A, Legleiter J. Sedighi F, et al. ACS Chem Neurosci. 2020 Feb 5;11(3):328-343. doi: 10.1021/acschemneuro.9b00509. Epub 2020 Jan 9. ACS Chem Neurosci. 2020. PMID: 31880908

4

Exploding the Repeat Length Paradigm while Exploring Amyloid Toxicity in Huntington's Disease.

Wetzel R. Wetzel R. Acc Chem Res. 2020 Oct 20;53(10):2347-2357. doi: 10.1021/acs.accounts.0c00450. Epub 2020 Sep 25. Acc Chem Res. 2020. PMID: 32975927

5

Phosphomimetic Mutations Impact Huntingtin Aggregation in the Presence of a Variety of Lipid Systems.

Groover SE, Beasley M, Ramamurthy V, Legleiter J. Groover SE, et al. Biochemistry. 2020 Dec 15;59(49):4681-4693. doi: 10.1021/acs.biochem.0c00788. Epub 2020 Nov 30. Biochemistry. 2020. PMID: 33256402

6

Cholesterol Modifies Huntingtin Binding to, Disruption of, and Aggregation on Lipid Membranes.

Gao X, Campbell WA 4th, Chaibva M, Jain P, Leslie AE, Frey SL, Legleiter J. Gao X, et al. Biochemistry. 2016 Jan 12;55(1):92-102. doi: 10.1021/acs.biochem.5b00900. Epub 2015 Dec 22. Biochemistry. 2016. PMID: 26652744 Free PMC article.

7

Aggregation landscapes of Huntingtin exon 1 protein fragments and the critical repeat length for the onset of Huntington's disease.

Chen M, Wolynes PG. Chen M, et al. Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):4406-4411. doi: 10.1073/pnas.1702237114. Epub 2017 Apr 11. Proc Natl Acad Sci U S A. 2017. PMID: 28400517 Free PMC article.

8

Inhibition of polyglutamine aggregation by SIMILAR huntingtin N-terminal sequences: Prospective molecules for preclinical evaluation in Huntington's disease.

Burra G, Thakur AK. Burra G, et al. Biopolymers. 2017 Jul;108(4). doi: 10.1002/bip.23021. Biopolymers. 2017. PMID: 28406522

9

Oxidation Promotes Distinct Huntingtin Aggregates in the Presence and Absence of Membranes.

Adegbuyiro A, Stonebraker AR, Sedighi F, Fan CK, Hodges B, Li P, Valentine SJ, Legleiter J. Adegbuyiro A, et al. Biochemistry. 2022 Jul 19;61(14):1517-1530. doi: 10.1021/acs.biochem.2c00212. Epub 2022 Jun 27. Biochemistry. 2022. PMID: 35759798 Free PMC article.

10

Physicochemical Properties Altered by the Tail Group of Lipid Membranes Influence Huntingtin Aggregation and Lipid Binding.

Beasley M, Frazee N, Groover S, Valentine SJ, Mertz B, Legleiter J. Beasley M, et al. J Phys Chem B. 2022 Apr 28;126(16):3067-3081. doi: 10.1021/acs.jpcb.1c10254. Epub 2022 Apr 19. J Phys Chem B. 2022. PMID: 35439000

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