Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 165

1.

AP-2-associated protein kinase 1 and cyclin G-associated kinase regulate hepatitis C virus entry and are potential drug targets.

Neveu G, Ziv-Av A, Barouch-Bentov R, Berkerman E, Mulholland J, Einav S.

J Virol. 2015 Apr;89(8):4387-404. doi: 10.1128/JVI.02705-14. Epub 2015 Feb 4.

2.

Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects.

Bekerman E, Neveu G, Shulla A, Brannan J, Pu SY, Wang S, Xiao F, Barouch-Bentov R, Bakken RR, Mateo R, Govero J, Nagamine CM, Diamond MS, De Jonghe S, Herdewijn P, Dye JM, Randall G, Einav S.

J Clin Invest. 2017 Apr 3;127(4):1338-1352. doi: 10.1172/JCI89857. Epub 2017 Feb 27.

3.

Identification and targeting of an interaction between a tyrosine motif within hepatitis C virus core protein and AP2M1 essential for viral assembly.

Neveu G, Barouch-Bentov R, Ziv-Av A, Gerber D, Jacob Y, Einav S.

PLoS Pathog. 2012;8(8):e1002845. doi: 10.1371/journal.ppat.1002845. Epub 2012 Aug 16.

4.

Interactions between the Hepatitis C Virus Nonstructural 2 Protein and Host Adaptor Proteins 1 and 4 Orchestrate Virus Release.

Xiao F, Wang S, Barouch-Bentov R, Neveu G, Pu S, Beer M, Schor S, Kumar S, Nicolaescu V, Lindenbach BD, Randall G, Einav S.

MBio. 2018 Mar 13;9(2). pii: e02233-17. doi: 10.1128/mBio.02233-17.

5.

Selective Inhibitors of Cyclin G Associated Kinase (GAK) as Anti-Hepatitis C Agents.

Kovackova S, Chang L, Bekerman E, Neveu G, Barouch-Bentov R, Chaikuad A, Heroven C, Šála M, De Jonghe S, Knapp S, Einav S, Herdewijn P.

J Med Chem. 2015 Apr 23;58(8):3393-410. doi: 10.1021/jm501759m. Epub 2015 Apr 9.

6.

Nonstructural 3 Protein of Hepatitis C Virus Modulates the Tribbles Homolog 3/Akt Signaling Pathway for Persistent Viral Infection.

Tran SC, Pham TM, Nguyen LN, Park EM, Lim YS, Hwang SB.

J Virol. 2016 Jul 27;90(16):7231-7247. doi: 10.1128/JVI.00326-16. Print 2016 Aug 15.

7.

EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy.

Lupberger J, Zeisel MB, Xiao F, Thumann C, Fofana I, Zona L, Davis C, Mee CJ, Turek M, Gorke S, Royer C, Fischer B, Zahid MN, Lavillette D, Fresquet J, Cosset FL, Rothenberg SM, Pietschmann T, Patel AH, Pessaux P, Doffoël M, Raffelsberger W, Poch O, McKeating JA, Brino L, Baumert TF.

Nat Med. 2011 May;17(5):589-95. doi: 10.1038/nm.2341. Epub 2011 Apr 24.

8.

Contrasting roles of mitogen-activated protein kinases in cellular entry and replication of hepatitis C virus: MKNK1 facilitates cell entry.

Kim S, Ishida H, Yamane D, Yi M, Swinney DC, Foung S, Lemon SM.

J Virol. 2013 Apr;87(8):4214-24. doi: 10.1128/JVI.00954-12. Epub 2013 Jan 30.

9.

Clathrin mediates infectious hepatitis C virus particle egress.

Benedicto I, Gondar V, Molina-Jiménez F, García-Buey L, López-Cabrera M, Gastaminza P, Majano PL.

J Virol. 2015 Apr;89(8):4180-90. doi: 10.1128/JVI.03620-14. Epub 2015 Jan 28.

10.

Involvement of hepatitis C virus NS5A hyperphosphorylation mediated by casein kinase I-α in infectious virus production.

Masaki T, Matsunaga S, Takahashi H, Nakashima K, Kimura Y, Ito M, Matsuda M, Murayama A, Kato T, Hirano H, Endo Y, Lemon SM, Wakita T, Sawasaki T, Suzuki T.

J Virol. 2014 Jul;88(13):7541-55. doi: 10.1128/JVI.03170-13. Epub 2014 Apr 23.

11.

AAK1 regulates Numb function at an early step in clathrin-mediated endocytosis.

Sorensen EB, Conner SD.

Traffic. 2008 Sep;9(10):1791-800. doi: 10.1111/j.1600-0854.2008.00790.x. Epub 2008 Jul 24.

12.

Gefitinib and luteolin cause growth arrest of human prostate cancer PC-3 cells via inhibition of cyclin G-associated kinase and induction of miR-630.

Sakurai MA, Ozaki Y, Okuzaki D, Naito Y, Sasakura T, Okamoto A, Tabara H, Inoue T, Hagiyama M, Ito A, Yabuta N, Nojima H.

PLoS One. 2014 Jun 27;9(6):e100124. doi: 10.1371/journal.pone.0100124. eCollection 2014.

13.

N-Myc Downstream-Regulated Gene 1 Restricts Hepatitis C Virus Propagation by Regulating Lipid Droplet Biogenesis and Viral Assembly.

Schweitzer CJ, Zhang F, Boyer A, Valdez K, Cam M, Liang TJ.

J Virol. 2018 Jan 2;92(2). pii: e01166-17. doi: 10.1128/JVI.01166-17. Print 2018 Jan 15.

14.

Pim Kinase Interacts with Nonstructural 5A Protein and Regulates Hepatitis C Virus Entry.

Park C, Min S, Park EM, Lim YS, Kang S, Suzuki T, Shin EC, Hwang SB.

J Virol. 2015 Oct;89(19):10073-86. doi: 10.1128/JVI.01707-15. Epub 2015 Jul 22.

15.

A novel AAK1 splice variant functions at multiple steps of the endocytic pathway.

Henderson DM, Conner SD.

Mol Biol Cell. 2007 Jul;18(7):2698-706. Epub 2007 May 9.

16.

Feasibility and biological rationale of repurposing sunitinib and erlotinib for dengue treatment.

Pu SY, Xiao F, Schor S, Bekerman E, Zanini F, Barouch-Bentov R, Nagamine CM, Einav S.

Antiviral Res. 2018 Jul;155:67-75. doi: 10.1016/j.antiviral.2018.05.001. Epub 2018 May 16.

PMID:
29753658
17.

Integrative functional genomics of hepatitis C virus infection identifies host dependencies in complete viral replication cycle.

Li Q, Zhang YY, Chiu S, Hu Z, Lan KH, Cha H, Sodroski C, Zhang F, Hsu CS, Thomas E, Liang TJ.

PLoS Pathog. 2014 May 22;10(5):e1004163. doi: 10.1371/journal.ppat.1004163. eCollection 2014 May.

18.

Hepatitis C virus induces epidermal growth factor receptor activation via CD81 binding for viral internalization and entry.

Diao J, Pantua H, Ngu H, Komuves L, Diehl L, Schaefer G, Kapadia SB.

J Virol. 2012 Oct;86(20):10935-49. Epub 2012 Aug 1.

19.

RNA interference and single particle tracking analysis of hepatitis C virus endocytosis.

Coller KE, Berger KL, Heaton NS, Cooper JD, Yoon R, Randall G.

PLoS Pathog. 2009 Dec;5(12):e1000702. doi: 10.1371/journal.ppat.1000702. Epub 2009 Dec 24.

20.

Identification of an adaptor-associated kinase, AAK1, as a regulator of clathrin-mediated endocytosis.

Conner SD, Schmid SL.

J Cell Biol. 2002 Mar 4;156(5):921-9. Epub 2002 Mar 4.

Supplemental Content

Support Center