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Items: 1 to 20 of 88

1.

Autophagy enhances NFκB activity in specific tissue macrophages by sequestering A20 to boost antifungal immunity.

Kanayama M, Inoue M, Danzaki K, Hammer G, He YW, Shinohara ML.

Nat Commun. 2015 Jan 22;6:5779. doi: 10.1038/ncomms6779.

2.

Elevated A20 contributes to age-dependent macrophage dysfunction in the lungs.

Hinojosa CA, Akula Suresh Babu R, Rahman MM, Fernandes G, Boyd AR, Orihuela CJ.

Exp Gerontol. 2014 Jun;54:58-66. doi: 10.1016/j.exger.2014.01.007. Epub 2014 Jan 17.

3.

A20 is an early responding negative regulator of Toll-like receptor 5 signalling in intestinal epithelial cells during inflammation.

Oshima N, Ishihara S, Rumi MA, Aziz MM, Mishima Y, Kadota C, Moriyama I, Ishimura N, Amano Y, Kinoshita Y.

Clin Exp Immunol. 2010 Feb;159(2):185-98. doi: 10.1111/j.1365-2249.2009.04048.x. Epub 2009 Nov 12.

4.

Leishmania donovani exploits host deubiquitinating enzyme A20, a negative regulator of TLR signaling, to subvert host immune response.

Srivastav S, Kar S, Chande AG, Mukhopadhyaya R, Das PK.

J Immunol. 2012 Jul 15;189(2):924-34. doi: 10.4049/jimmunol.1102845. Epub 2012 Jun 8.

5.

A20 (Tnfaip3) deficiency in myeloid cells protects against influenza A virus infection.

Maelfait J, Roose K, Bogaert P, Sze M, Saelens X, Pasparakis M, Carpentier I, van Loo G, Beyaert R.

PLoS Pathog. 2012;8(3):e1002570. doi: 10.1371/journal.ppat.1002570. Epub 2012 Mar 1. Erratum in: PLoS Pathog. 2012 Apr;8(4): doi/10.1371/annotation/a2136b9a-3cbf-426f-9cfb-73e3c9c6396d.

6.

Macrophage autophagy in immunity to Cryptococcus neoformans and Candida albicans.

Nicola AM, Albuquerque P, Martinez LR, Dal-Rosso RA, Saylor C, De Jesus M, Nosanchuk JD, Casadevall A.

Infect Immun. 2012 Sep;80(9):3065-76. doi: 10.1128/IAI.00358-12. Epub 2012 Jun 18.

7.

The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals.

Hitotsumatsu O, Ahmad RC, Tavares R, Wang M, Philpott D, Turer EE, Lee BL, Shiffin N, Advincula R, Malynn BA, Werts C, Ma A.

Immunity. 2008 Mar;28(3):381-90. doi: 10.1016/j.immuni.2008.02.002.

8.

Deubiquitinating enzyme A20 negatively regulates NF-κB signaling in skeletal muscle in mdx mice.

Charan RA, Hanson R, Clemens PR.

FASEB J. 2012 Feb;26(2):587-95. doi: 10.1096/fj.11-189829. Epub 2011 Oct 19. Erratum in: FASEB J. 2013 Jan;27(1):410.

PMID:
22012122
9.

Mast cell and macrophage chemokines CXCL1/CXCL2 control the early stage of neutrophil recruitment during tissue inflammation.

De Filippo K, Dudeck A, Hasenberg M, Nye E, van Rooijen N, Hartmann K, Gunzer M, Roers A, Hogg N.

Blood. 2013 Jun 13;121(24):4930-7. doi: 10.1182/blood-2013-02-486217. Epub 2013 May 3.

10.

Vitamin E γ-Tocotrienol Inhibits Cytokine-Stimulated NF-κB Activation by Induction of Anti-Inflammatory A20 via Stress Adaptive Response Due to Modulation of Sphingolipids.

Wang Y, Park NY, Jang Y, Ma A, Jiang Q.

J Immunol. 2015 Jul 1;195(1):126-33. doi: 10.4049/jimmunol.1403149. Epub 2015 May 22.

11.

The deubiquitinase activity of A20 is dispensable for NF-κB signaling.

De A, Dainichi T, Rathinam CV, Ghosh S.

EMBO Rep. 2014 Jul;15(7):775-83. doi: 10.15252/embr.201338305. Epub 2014 May 30.

12.

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis.

Matmati M, Jacques P, Maelfait J, Verheugen E, Kool M, Sze M, Geboes L, Louagie E, Mc Guire C, Vereecke L, Chu Y, Boon L, Staelens S, Matthys P, Lambrecht BN, Schmidt-Supprian M, Pasparakis M, Elewaut D, Beyaert R, van Loo G.

Nat Genet. 2011 Aug 14;43(9):908-12. doi: 10.1038/ng.874.

PMID:
21841782
13.

Absence of functional TLR4 impairs response of macrophages after Candida albicans infection.

Gasparoto TH, Tessarolli V, Garlet TP, Torres SA, Garlet GP, da Silva JS, Campanelli AP.

Med Mycol. 2010 Dec;48(8):1009-17. doi: 10.3109/13693786.2010.481292. Epub 2010 May 14.

PMID:
20465519
14.

Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment.

Martinez-Outschoorn UE, Trimmer C, Lin Z, Whitaker-Menezes D, Chiavarina B, Zhou J, Wang C, Pavlides S, Martinez-Cantarin MP, Capozza F, Witkiewicz AK, Flomenberg N, Howell A, Pestell RG, Caro J, Lisanti MP, Sotgia F.

Cell Cycle. 2010 Sep 1;9(17):3515-33. Epub 2010 Sep 9.

15.

A20, a regulator of NFkappaB, maps to an atherosclerosis locus and differs between parental sensitive C57BL/6J and resistant FVB/N strains.

Idel S, Dansky HM, Breslow JL.

Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14235-40. Epub 2003 Nov 12.

16.

SYK regulates macrophage MHC-II expression via activation of autophagy in response to oxidized LDL.

Choi SH, Gonen A, Diehl CJ, Kim J, Almazan F, Witztum JL, Miller YI.

Autophagy. 2015;11(5):785-95. doi: 10.1080/15548627.2015.1037061.

17.

The Src-Family Kinases Hck and Fgr Regulate Early Lipopolysaccharide-Induced Myeloid Cell Recruitment into the Lung and Their Ability To Secrete Chemokines.

Mazzi P, Caveggion E, Lapinet-Vera JA, Lowell CA, Berton G.

J Immunol. 2015 Sep 1;195(5):2383-95. doi: 10.4049/jimmunol.1402011. Epub 2015 Jul 31.

18.

Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis.

Vereecke L, Sze M, Mc Guire C, Rogiers B, Chu Y, Schmidt-Supprian M, Pasparakis M, Beyaert R, van Loo G.

J Exp Med. 2010 Jul 5;207(7):1513-23. doi: 10.1084/jem.20092474. Epub 2010 Jun 7.

19.

MicroRNA-873 Inhibits Morphine-Induced Macrophage Apoptosis by Elevating A20 Expression.

Li MC, Yu JH, Yu SS, Chi YY, Xiang YB.

Pain Med. 2015 Oct;16(10):1993-9. doi: 10.1111/pme.12784. Epub 2015 May 19.

PMID:
25989384
20.

Nod2 and Rip2 contribute to innate immune responses in mouse neutrophils.

Jeong YJ, Kang MJ, Lee SJ, Kim CH, Kim JC, Kim TH, Kim DJ, Kim D, Núñez G, Park JH.

Immunology. 2014 Oct;143(2):269-76. doi: 10.1111/imm.12307.

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