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Items: 1 to 20 of 79

1.

The energy sensor AMPK regulates T cell metabolic adaptation and effector responses in vivo.

Blagih J, Coulombe F, Vincent EE, Dupuy F, Galicia-Vázquez G, Yurchenko E, Raissi TC, van der Windt GJ, Viollet B, Pearce EL, Pelletier J, Piccirillo CA, Krawczyk CM, Divangahi M, Jones RG.

Immunity. 2015 Jan 20;42(1):41-54. doi: 10.1016/j.immuni.2014.12.030. Epub 2015 Jan 2.

2.

AMPK helps T cells survive nutrient starvation.

Yang K, Chi H.

Immunity. 2015 Jan 20;42(1):4-6. doi: 10.1016/j.immuni.2014.12.029.

3.

AMPKα1: a glucose sensor that controls CD8 T-cell memory.

Rolf J, Zarrouk M, Finlay DK, Foretz M, Viollet B, Cantrell DA.

Eur J Immunol. 2013 Apr;43(4):889-96. doi: 10.1002/eji.201243008. Epub 2013 Feb 13.

4.

AMP-activated protein kinase regulates lymphocyte responses to metabolic stress but is largely dispensable for immune cell development and function.

Mayer A, Denanglaire S, Viollet B, Leo O, Andris F.

Eur J Immunol. 2008 Apr;38(4):948-56. doi: 10.1002/eji.200738045.

5.

The AMPK β2 subunit is required for energy homeostasis during metabolic stress.

Dasgupta B, Ju JS, Sasaki Y, Liu X, Jung SR, Higashida K, Lindquist D, Milbrandt J.

Mol Cell Biol. 2012 Jul;32(14):2837-48. doi: 10.1128/MCB.05853-11. Epub 2012 May 14.

7.

Fine-Tuning of CD8(+) T Cell Mitochondrial Metabolism by the Respiratory Chain Repressor MCJ Dictates Protection to Influenza Virus.

Champagne DP, Hatle KM, Fortner KA, D'Alessandro A, Thornton TM, Yang R, Torralba D, Tomás-Cortázar J, Jun YW, Ahn KH, Hansen KC, Haynes L, Anguita J, Rincon M.

Immunity. 2016 Jun 21;44(6):1299-311. doi: 10.1016/j.immuni.2016.02.018. Epub 2016 May 24.

8.

Metabolic sensor AMPK directly phosphorylates RAG1 protein and regulates V(D)J recombination.

Um JH, Brown AL, Singh SK, Chen Y, Gucek M, Lee BS, Luckey MA, Kim MK, Park JH, Sleckman BP, Gellert M, Chung JH.

Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9873-8. doi: 10.1073/pnas.1307928110. Epub 2013 May 28.

9.

AMPKα1 controls hepatocyte proliferation independently of energy balance by regulating Cyclin A2 expression.

Merlen G, Gentric G, Celton-Morizur S, Foretz M, Guidotti JE, Fauveau V, Leclerc J, Viollet B, Desdouets C.

J Hepatol. 2014 Jan;60(1):152-9. doi: 10.1016/j.jhep.2013.08.025. Epub 2013 Sep 6.

PMID:
24012615
10.

The serine/threonine kinase LKB1 controls thymocyte survival through regulation of AMPK activation and Bcl-XL expression.

Cao Y, Li H, Liu H, Zheng C, Ji H, Liu X.

Cell Res. 2010 Jan;20(1):99-108. doi: 10.1038/cr.2009.141. Epub 2009 Dec 22.

PMID:
20029389
11.

AMPK controls exercise endurance, mitochondrial oxidative capacity, and skeletal muscle integrity.

Lantier L, Fentz J, Mounier R, Leclerc J, Treebak JT, Pehmøller C, Sanz N, Sakakibara I, Saint-Amand E, Rimbaud S, Maire P, Marette A, Ventura-Clapier R, Ferry A, Wojtaszewski JF, Foretz M, Viollet B.

FASEB J. 2014 Jul;28(7):3211-24. doi: 10.1096/fj.14-250449. Epub 2014 Mar 20.

PMID:
24652947
12.

AMPK in lymphocyte metabolism and function.

Andris F, Leo O.

Int Rev Immunol. 2015 Jan;34(1):67-81. doi: 10.3109/08830185.2014.969422. Epub 2014 Oct 31. Review.

PMID:
25360847
13.

Compensatory regulation of HDAC5 in muscle maintains metabolic adaptive responses and metabolism in response to energetic stress.

McGee SL, Swinton C, Morrison S, Gaur V, Campbell DE, Jorgensen SB, Kemp BE, Baar K, Steinberg GR, Hargreaves M.

FASEB J. 2014 Aug;28(8):3384-95. doi: 10.1096/fj.14-249359. Epub 2014 Apr 14.

PMID:
24732133
14.

The role of AMPK in T cell metabolism and function.

Ma EH, Poffenberger MC, Wong AH, Jones RG.

Curr Opin Immunol. 2017 Jun;46:45-52. doi: 10.1016/j.coi.2017.04.004. Epub 2017 Apr 28. Review.

PMID:
28460345
15.

Protective CD8 T cell memory is impaired during chronic CD70-driven costimulation.

van Gisbergen KP, van Olffen RW, van Beek J, van der Sluijs KF, Arens R, Nolte MA, van Lier RA.

J Immunol. 2009 May 1;182(9):5352-62. doi: 10.4049/jimmunol.0802809.

16.

Metabolic regulation of neuronal plasticity by the energy sensor AMPK.

Potter WB, O'Riordan KJ, Barnett D, Osting SM, Wagoner M, Burger C, Roopra A.

PLoS One. 2010 Feb 1;5(2):e8996. doi: 10.1371/journal.pone.0008996.

17.

Unlike CD4+ T-cell help, CD28 costimulation is necessary for effective primary CD8+ T-cell influenza-specific immunity.

Seah SG, Carrington EM, Ng WC, Belz GT, Brady JL, Sutherland RM, Hancock MS, La Gruta NL, Brown LE, Turner SJ, Zhan Y, Lew AM.

Eur J Immunol. 2012 Jul;42(7):1744-54. doi: 10.1002/eji.201142211. Epub 2012 Jun 14.

18.

Inducible bronchus-associated lymphoid tissue (iBALT) synergizes with local lymph nodes during antiviral CD4+ T cell responses.

Richert LE, Harmsen AL, Rynda-Apple A, Wiley JA, Servid AE, Douglas T, Harmsen AG.

Lymphat Res Biol. 2013 Dec;11(4):196-202. doi: 10.1089/lrb.2013.0015.

19.

LKB1 and AMPK: central regulators of lymphocyte metabolism and function.

Blagih J, Krawczyk CM, Jones RG.

Immunol Rev. 2012 Sep;249(1):59-71. doi: 10.1111/j.1600-065X.2012.01157.x. Review.

PMID:
22889215
20.

Severe influenza A(H1N1)pdm09 infection induces thymic atrophy through activating innate CD8(+)CD44(hi) T cells by upregulating IFN-γ.

Liu B, Zhang X, Deng W, Liu J, Li H, Wen M, Bao L, Qu J, Liu Y, Li F, An Y, Qin C, Cao B, Wang C.

Cell Death Dis. 2014 Oct 2;5:e1440. doi: 10.1038/cddis.2014.323.

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