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Items: 1 to 20 of 115

1.

Natural IgM prevents autoimmunity by enforcing B cell central tolerance induction.

Nguyen TT, Elsner RA, Baumgarth N.

J Immunol. 2015 Feb 15;194(4):1489-502. doi: 10.4049/jimmunol.1401880. Epub 2015 Jan 16.

3.

Negative selection by IgM superantigen defines a B cell central tolerance compartment and reveals mutations allowing escape.

Duong BH, Ota T, Aoki-Ota M, Cooper AB, Ait-Azzouzene D, Vela JL, Gavin AL, Nemazee D.

J Immunol. 2011 Dec 1;187(11):5596-605. doi: 10.4049/jimmunol.1102479. Epub 2011 Oct 31.

4.

CD19-regulated signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes.

Inaoki M, Sato S, Weintraub BC, Goodnow CC, Tedder TF.

J Exp Med. 1997 Dec 1;186(11):1923-31.

5.

CD22 x Siglec-G double-deficient mice have massively increased B1 cell numbers and develop systemic autoimmunity.

Jellusova J, Wellmann U, Amann K, Winkler TH, Nitschke L.

J Immunol. 2010 Apr 1;184(7):3618-27. doi: 10.4049/jimmunol.0902711. Epub 2010 Mar 3.

6.

TLR9 in peritoneal B-1b cells is essential for production of protective self-reactive IgM to control Th17 cells and severe autoimmunity.

Stoehr AD, Schoen CT, Mertes MM, Eiglmeier S, Holecska V, Lorenz AK, Schommartz T, Schoen AL, Hess C, Winkler A, Wardemann H, Ehlers M.

J Immunol. 2011 Sep 15;187(6):2953-65. doi: 10.4049/jimmunol.1003340. Epub 2011 Aug 22.

7.

Anergic responses characterize a large fraction of human autoreactive naive B cells expressing low levels of surface IgM.

Quách TD, Manjarrez-Orduño N, Adlowitz DG, Silver L, Yang H, Wei C, Milner EC, Sanz I.

J Immunol. 2011 Apr 15;186(8):4640-8. doi: 10.4049/jimmunol.1001946. Epub 2011 Mar 11.

8.

Loss of tolerance of anti-dsDNA B cells in mice overexpressing CD19.

Taylor DK, Ito E, Thorn M, Sundar K, Tedder T, Spatz LA.

Mol Immunol. 2006 Apr;43(11):1776-90. Epub 2006 Jan 20.

PMID:
16430962
9.

Modulation of peripheral B cell tolerance by CD72 in a murine model.

Li DH, Winslow MM, Cao TM, Chen AH, Davis CR, Mellins ED, Utz PJ, Crabtree GR, Parnes JR.

Arthritis Rheum. 2008 Oct;58(10):3192-204. doi: 10.1002/art.23812.

10.

Surrogate light chain is required for central and peripheral B-cell tolerance and inhibits anti-DNA antibody production by marginal zone B cells.

Ren W, Grimsholm O, Bernardi AI, Höök N, Stern A, Cavallini N, Mårtensson IL.

Eur J Immunol. 2015 Apr;45(4):1228-37. doi: 10.1002/eji.201444917. Epub 2015 Jan 22.

11.

Rheumatoid arthritis is associated with signaling alterations in naturally occurring autoreactive B-lymphocytes.

Liubchenko GA, Appleberry HC, Striebich CC, Franklin KE, Derber LA, Holers VM, Lyubchenko T.

J Autoimmun. 2013 Feb;40:111-21. doi: 10.1016/j.jaut.2012.09.001. Epub 2012 Oct 8.

12.
13.

JNK regulatory molecule G5PR induces IgG autoantibody-producing plasmablasts from peritoneal B1a cells.

Kitabatake M, Soma M, Zhang T, Kuwahara K, Fukushima Y, Nojima T, Kitamura D, Sakaguchi N.

J Immunol. 2015 Feb 15;194(4):1480-8. doi: 10.4049/jimmunol.1401127. Epub 2015 Jan 19.

14.

Reversing Tolerance in Isotype Switch-Competent Anti-Insulin B Lymphocytes.

Williams JM, Bonami RH, Hulbert C, Thomas JW.

J Immunol. 2015 Aug 1;195(3):853-64. doi: 10.4049/jimmunol.1403114. Epub 2015 Jun 24.

15.

Endogenous antigen tunes the responsiveness of naive B cells but not T cells.

Zikherman J, Parameswaran R, Weiss A.

Nature. 2012 Sep 6;489(7414):160-4. doi: 10.1038/nature11311.

16.

Natural IgM and the Development of B Cell-Mediated Autoimmune Diseases.

Nguyen TT, Baumgarth N.

Crit Rev Immunol. 2016;36(2):163-177. Review.

17.

Genetic Interaction between Lyn, Ets1, and Btk in the Control of Antibody Levels.

Mayeux J, Skaug B, Luo W, Russell LM, John S, Saelee P, Abbasi H, Li QZ, Garrett-Sinha LA, Satterthwaite AB.

J Immunol. 2015 Sep 1;195(5):1955-63. doi: 10.4049/jimmunol.1500165. Epub 2015 Jul 24.

18.

Identification of anergic B cells within a wild-type repertoire.

Merrell KT, Benschop RJ, Gauld SB, Aviszus K, Decote-Ricardo D, Wysocki LJ, Cambier JC.

Immunity. 2006 Dec;25(6):953-62.

19.

Functionally responsive self-reactive B cells of low affinity express reduced levels of surface IgM.

Kirchenbaum GA, St Clair JB, Detanico T, Aviszus K, Wysocki LJ.

Eur J Immunol. 2014 Apr;44(4):970-82. doi: 10.1002/eji.201344276. Epub 2014 Jan 20.

20.

Regulatory CD4+ T cells promote B cell anergy in murine lupus.

Liu Y, Liu A, Iikuni N, Xu H, Shi FD, La Cava A.

J Immunol. 2014 May 1;192(9):4069-73. doi: 10.4049/jimmunol.1302897. Epub 2014 Mar 26.

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