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Items: 1 to 20 of 97

1.

Identification of Biological Relevant Minor Histocompatibility Antigens within the B-lymphocyte-Derived HLA-Ligandome Using a Reverse Immunology Approach.

Hombrink P, Hassan C, Kester MG, Jahn L, Pont MJ, de Ru AH, van Bergen CA, Griffioen M, Falkenburg JH, van Veelen PA, Heemskerk MH.

Clin Cancer Res. 2015 May 1;21(9):2177-86. doi: 10.1158/1078-0432.CCR-14-2188. Epub 2015 Jan 14.

2.

Collateral damage of nonhematopoietic tissue by hematopoiesis-specific T cells results in graft-versus-host disease during an ongoing profound graft-versus-leukemia reaction.

van der Zouwen B, Kruisselbrink AB, Frederik Falkenburg JH, Jedema I.

Biol Blood Marrow Transplant. 2014 Jun;20(6):760-9. doi: 10.1016/j.bbmt.2014.03.002. Epub 2014 Mar 7.

3.

Discovery of T cell epitopes implementing HLA-peptidomics into a reverse immunology approach.

Hombrink P, Hassan C, Kester MG, de Ru AH, van Bergen CA, Nijveen H, Drijfhout JW, Falkenburg JH, Heemskerk MH, van Veelen PA.

J Immunol. 2013 Apr 15;190(8):3869-77. doi: 10.4049/jimmunol.1202351. Epub 2013 Mar 8.

4.

High-throughput characterization of 10 new minor histocompatibility antigens by whole genome association scanning.

Van Bergen CA, Rutten CE, Van Der Meijden ED, Van Luxemburg-Heijs SA, Lurvink EG, Houwing-Duistermaat JJ, Kester MG, Mulder A, Willemze R, Falkenburg JH, Griffioen M.

Cancer Res. 2010 Nov 15;70(22):9073-83. doi: 10.1158/0008-5472.CAN-10-1832. Epub 2010 Nov 9.

5.

Concurrent detection of circulating minor histocompatibility antigen-specific CD8+ T cells in SCT recipients by combinatorial encoding MHC multimers.

Broen K, Greupink-Draaisma A, Woestenenk R, Schaap N, Brickner AG, Dolstra H.

PLoS One. 2011;6(6):e21266. doi: 10.1371/journal.pone.0021266. Epub 2011 Jun 24.

6.

High-throughput identification of potential minor histocompatibility antigens by MHC tetramer-based screening: feasibility and limitations.

Hombrink P, Hadrup SR, Bakker A, Kester MG, Falkenburg JH, von dem Borne PA, Schumacher TN, Heemskerk MH.

PLoS One. 2011;6(8):e22523. doi: 10.1371/journal.pone.0022523. Epub 2011 Aug 5.

7.

Diverse patterns of T-cell response against multiple newly identified human Y chromosome-encoded minor histocompatibility epitopes.

Ofran Y, Kim HT, Brusic V, Blake L, Mandrell M, Wu CJ, Sarantopoulos S, Bellucci R, Keskin DB, Soiffer RJ, Antin JH, Ritz J.

Clin Cancer Res. 2010 Mar 1;16(5):1642-51. doi: 10.1158/1078-0432.CCR-09-2701. Epub 2010 Feb 16.

8.

Integrated Whole Genome and Transcriptome Analysis Identified a Therapeutic Minor Histocompatibility Antigen in a Splice Variant of ITGB2.

Pont MJ, van der Lee DI, van der Meijden ED, van Bergen CA, Kester MG, Honders MW, Vermaat M, Eefting M, Marijt EW, Kielbasa SM, Hoen PA, Falkenburg JH, Griffioen M.

Clin Cancer Res. 2016 Aug 15;22(16):4185-96. doi: 10.1158/1078-0432.CCR-15-2307. Epub 2016 Mar 10.

9.

Degree of predicted minor histocompatibility antigen mismatch correlates with poorer clinical outcomes in nonmyeloablative allogeneic hematopoietic cell transplantation.

Larsen ME, Kornblit B, Larsen MV, Masmas TN, Nielsen M, Thiim M, Garred P, Stryhn A, Lund O, Buus S, Vindelov L.

Biol Blood Marrow Transplant. 2010 Oct;16(10):1370-81. doi: 10.1016/j.bbmt.2010.03.022. Epub 2010 Mar 28.

10.

Identification of 4 novel HLA-B*40:01 restricted minor histocompatibility antigens and their potential as targets for graft-versus-leukemia reactivity.

Griffioen M, Honders MW, van der Meijden ED, van Luxemburg-Heijs SA, Lurvink EG, Kester MG, van Bergen CA, Falkenburg JH.

Haematologica. 2012 Aug;97(8):1196-204. doi: 10.3324/haematol.2011.049478. Epub 2012 Mar 14.

11.

Towards effective and safe immunotherapy after allogeneic stem cell transplantation: identification of hematopoietic-specific minor histocompatibility antigen UTA2-1.

Oostvogels R, Minnema MC, van Elk M, Spaapen RM, te Raa GD, Giovannone B, Buijs A, van Baarle D, Kater AP, Griffioen M, Spierings E, Lokhorst HM, Mutis T.

Leukemia. 2013 Mar;27(3):642-9. doi: 10.1038/leu.2012.277. Epub 2012 Oct 1.

13.

CD4(+)and CD8(+)T-cell reactions against leukemia-associated- or minor-histocompatibility-antigens in AML-patients after allogeneic SCT.

Steger B, Milosevic S, Doessinger G, Reuther S, Liepert A, Braeu M, Schick J, Vogt V, Schuster F, Kroell T, Busch DH, Borkhardt A, Kolb HJ, Tischer J, Buhmann R, Schmetzer H.

Immunobiology. 2014 Apr;219(4):247-60. doi: 10.1016/j.imbio.2013.10.008. Epub 2013 Oct 27.

PMID:
24315637
14.

Minor histocompatibility antigens--targets of graft versus leukemia responses.

Riddell SR, Murata M, Bryant S, Warren EH.

Int J Hematol. 2002 Aug;76 Suppl 2:155-61. Review.

PMID:
12430918
15.

miHA-Match: computational detection of tissue-specific minor histocompatibility antigens.

Feldhahn M, Dönnes P, Schubert B, Schilbach K, Rammensee HG, Kohlbacher O.

J Immunol Methods. 2012 Dec 14;386(1-2):94-100. doi: 10.1016/j.jim.2012.09.004. Epub 2012 Sep 14.

PMID:
22985828
16.

Promiscuity of the AlloHLA-A2 restricted T cell repertoire hampers the generation of minor Histocompatibility antigen-specific cytotoxic T cells across HLA barriers.

Oosten LE, Blokland E, Kester MG, Falkenburg JH, van Halteren AG, Goulmy E.

Biol Blood Marrow Transplant. 2007 Feb;13(2):151-63.

17.

B and T lymphocyte attenuator mediates inhibition of tumor-reactive CD8+ T cells in patients after allogeneic stem cell transplantation.

Hobo W, Norde WJ, Schaap N, Fredrix H, Maas F, Schellens K, Falkenburg JH, Korman AJ, Olive D, van der Voort R, Dolstra H.

J Immunol. 2012 Jul 1;189(1):39-49. doi: 10.4049/jimmunol.1102807. Epub 2012 May 25.

18.

Common minor histocompatibility antigen discovery based upon patient clinical outcomes and genomic data.

Armistead PM, Liang S, Li H, Lu S, Van Bergen CA, Alatrash G, St John L, Hunsucker SA, Sarantopoulos S, Falkenburg JH, Molldrem JJ.

PLoS One. 2011;6(8):e23217. doi: 10.1371/journal.pone.0023217. Epub 2011 Aug 9.

19.

Strategies for the identification of T cell-recognized tumor antigens in hematological malignancies for improved graft-versus-tumor responses after allogeneic blood and marrow transplantation.

Zilberberg J, Feinman R, Korngold R.

Biol Blood Marrow Transplant. 2015 Jun;21(6):1000-7. doi: 10.1016/j.bbmt.2014.11.001. Epub 2014 Nov 20. Review.

20.

Minor histocompatibility antigens as targets of graft-versus-leukemia reactions.

Falkenburg JH, Marijt WA, Heemskerk MH, Willemze R.

Curr Opin Hematol. 2002 Nov;9(6):497-502. Review.

PMID:
12394171

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