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Items: 1 to 20 of 127

1.

The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections.

Jaeger M, van der Lee R, Cheng SC, Johnson MD, Kumar V, Ng A, Plantinga TS, Smeekens SP, Oosting M, Wang X, Barchet W, Fitzgerald K, Joosten LAB, Perfect JR, Wijmenga C, van de Veerdonk FL, Huynen MA, Xavier RJ, Kullberg BJ, Netea MG.

Eur J Clin Microbiol Infect Dis. 2015 May;34(5):963-974. doi: 10.1007/s10096-014-2309-2. Epub 2015 Jan 13.

2.

The essential, nonredundant roles of RIG-I and MDA5 in detecting and controlling West Nile virus infection.

Errett JS, Suthar MS, McMillan A, Diamond MS, Gale M Jr.

J Virol. 2013 Nov;87(21):11416-25. doi: 10.1128/JVI.01488-13. Epub 2013 Aug 21.

3.

TRIM13 is a negative regulator of MDA5-mediated type I interferon production.

Narayan K, Waggoner L, Pham ST, Hendricks GL, Waggoner SN, Conlon J, Wang JP, Fitzgerald KA, Kang J.

J Virol. 2014 Sep;88(18):10748-57. doi: 10.1128/JVI.02593-13. Epub 2014 Jul 9.

4.

Effects of type 1 diabetes-associated IFIH1 polymorphisms on MDA5 function and expression.

Looney BM, Xia CQ, Concannon P, Ostrov DA, Clare-Salzler MJ.

Curr Diab Rep. 2015 Nov;15(11):96. doi: 10.1007/s11892-015-0656-8. Review.

PMID:
26385483
5.

EFTUD2 Is a Novel Innate Immune Regulator Restricting Hepatitis C Virus Infection through the RIG-I/MDA5 Pathway.

Zhu C, Xiao F, Hong J, Wang K, Liu X, Cai D, Fusco DN, Zhao L, Jeong SW, Brisac C, Chusri P, Schaefer EA, Zhao H, Peng LF, Lin W, Chung RT.

J Virol. 2015 Jul;89(13):6608-18. doi: 10.1128/JVI.00364-15. Epub 2015 Apr 15.

6.

Establishment and maintenance of the innate antiviral response to West Nile Virus involves both RIG-I and MDA5 signaling through IPS-1.

Fredericksen BL, Keller BC, Fornek J, Katze MG, Gale M Jr.

J Virol. 2008 Jan;82(2):609-16. Epub 2007 Oct 31.

7.

Toll-like receptor 3 and RIG-I-like receptor activation induces innate antiviral responses in mouse ovarian granulosa cells.

Yan K, Zhu W, Yu L, Li N, Zhang X, Liu P, Chen Q, Chen Y, Han D.

Mol Cell Endocrinol. 2013 Jun 15;372(1-2):73-85. doi: 10.1016/j.mce.2013.03.027. Epub 2013 Apr 6.

PMID:
23567548
8.

Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B.

Kitai Y, Takeuchi O, Kawasaki T, Ori D, Sueyoshi T, Murase M, Akira S, Kawai T.

J Biol Chem. 2015 Jan 9;290(2):1269-80. doi: 10.1074/jbc.M114.611053. Epub 2014 Dec 1.

9.

Pattern recognition receptor MDA5 modulates CD8+ T cell-dependent clearance of West Nile virus from the central nervous system.

Lazear HM, Pinto AK, Ramos HJ, Vick SC, Shrestha B, Suthar MS, Gale M Jr, Diamond MS.

J Virol. 2013 Nov;87(21):11401-15. doi: 10.1128/JVI.01403-13. Epub 2013 Aug 21.

10.

RIG-I, MDA5 and TLR3 synergistically play an important role in restriction of dengue virus infection.

Nasirudeen AM, Wong HH, Thien P, Xu S, Lam KP, Liu DX.

PLoS Negl Trop Dis. 2011 Jan 4;5(1):e926. doi: 10.1371/journal.pntd.0000926.

11.

LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses.

Satoh T, Kato H, Kumagai Y, Yoneyama M, Sato S, Matsushita K, Tsujimura T, Fujita T, Akira S, Takeuchi O.

Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1512-7. doi: 10.1073/pnas.0912986107. Epub 2010 Jan 8.

12.

Enterovirus 2Apro targets MDA5 and MAVS in infected cells.

Feng Q, Langereis MA, Lork M, Nguyen M, Hato SV, Lanke K, Emdad L, Bhoopathi P, Fisher PB, Lloyd RE, van Kuppeveld FJ.

J Virol. 2014 Mar;88(6):3369-78. doi: 10.1128/JVI.02712-13. Epub 2014 Jan 3.

13.

Double-stranded RNA induces an antiviral defense status in epidermal keratinocytes through TLR3-, PKR-, and MDA5/RIG-I-mediated differential signaling.

Kalali BN, Köllisch G, Mages J, Müller T, Bauer S, Wagner H, Ring J, Lang R, Mempel M, Ollert M.

J Immunol. 2008 Aug 15;181(4):2694-704.

14.

Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity.

Loo YM, Fornek J, Crochet N, Bajwa G, Perwitasari O, Martinez-Sobrido L, Akira S, Gill MA, García-Sastre A, Katze MG, Gale M Jr.

J Virol. 2008 Jan;82(1):335-45. Epub 2007 Oct 17.

15.

MDA5 Is Critical to Host Defense during Infection with Murine Coronavirus.

Zalinger ZB, Elliott R, Rose KM, Weiss SR.

J Virol. 2015 Dec;89(24):12330-40. doi: 10.1128/JVI.01470-15. Epub 2015 Sep 30.

16.

Sustained activation of interferon regulatory factor 3 during infection by paramyxoviruses requires MDA5.

Grandvaux N, Guan X, Yoboua F, Zucchini N, Fink K, Doyon P, Martin L, Servant MJ, Chartier S.

J Innate Immun. 2014;6(5):650-62. doi: 10.1159/000360764. Epub 2014 Apr 30.

17.

TLR4 signaling induces retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5 in mesangial cells.

Imaizumi T, Aizawa-Yashiro T, Watanabe S, Matsumiya T, Yoshida H, Tatsuta T, Xing F, Meng P, Hayakari R, Tsuruga K, Tanaka H.

J Nephrol. 2013 Sep-Oct;26(5):886-93. doi: 10.5301/jn.5000254. Epub 2013 Apr 5.

PMID:
23559071
18.

A selective contribution of the RIG-I-like receptor pathway to type I interferon responses activated by cytosolic DNA.

Choi MK, Wang Z, Ban T, Yanai H, Lu Y, Koshiba R, Nakaima Y, Hangai S, Savitsky D, Nakasato M, Negishi H, Takeuchi O, Honda K, Akira S, Tamura T, Taniguchi T.

Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17870-5. doi: 10.1073/pnas.0909545106. Epub 2009 Oct 1.

19.

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses.

Kato H, Takeuchi O, Sato S, Yoneyama M, Yamamoto M, Matsui K, Uematsu S, Jung A, Kawai T, Ishii KJ, Yamaguchi O, Otsu K, Tsujimura T, Koh CS, Reis e Sousa C, Matsuura Y, Fujita T, Akira S.

Nature. 2006 May 4;441(7089):101-5. Epub 2006 Apr 9.

PMID:
16625202
20.

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