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Luteolin protects against vascular inflammation in mice and TNF-alpha-induced monocyte adhesion to endothelial cells via suppressing IΚBα/NF-κB signaling pathway.

Jia Z, Nallasamy P, Liu D, Shah H, Li JZ, Chitrakar R, Si H, McCormick J, Zhu H, Zhen W, Li Y. Jia Z, et al. J Nutr Biochem. 2015 Mar;26(3):293-302. doi: 10.1016/j.jnutbio.2014.11.008. Epub 2014 Dec 15. J Nutr Biochem. 2015. PMID: 25577468 Free PMC article.

Sulforaphane reduces vascular inflammation in mice and prevents TNF-α-induced monocyte adhesion to primary endothelial cells through interfering with the NF-κB pathway.

Nallasamy P, Si H, Babu PV, Pan D, Fu Y, Brooke EA, Shah H, Zhen W, Zhu H, Liu D, Li Y, Jia Z. Nallasamy P, et al. J Nutr Biochem. 2014 Aug;25(8):824-33. doi: 10.1016/j.jnutbio.2014.03.011. Epub 2014 Apr 4. J Nutr Biochem. 2014. PMID: 24880493 Free PMC article.

ZLJ-6, a novel COX/5-LOX inhibitor, attenuates TNF-α-induced endothelial E-selectin, ICAM-1 and VCAM-1 expression and monocyte-endothelial interactions via a COX/5-LOX-independent mechanism.

Chen L, Zhao Q, Wang XL, You R, Zhang YH, Ji H, Lai YS. Chen L, et al. Vascul Pharmacol. 2011 Nov-Dec;55(5-6):135-42. doi: 10.1016/j.vph.2011.07.003. Epub 2011 Jul 12. Vascul Pharmacol. 2011. PMID: 21777697

Combination of curcumin and luteolin synergistically inhibits TNF-α-induced vascular inflammation in human vascular cells and mice.

Zhang L, Wang X, Zhang L, Virgous C, Si H. Zhang L, et al. J Nutr Biochem. 2019 Nov;73:108222. doi: 10.1016/j.jnutbio.2019.108222. Epub 2019 Aug 15. J Nutr Biochem. 2019. PMID: 31665675

Docosahexaenoic acid attenuates VCAM-1 expression and NF-κB activation in TNF-α-treated human aortic endothelial cells.

Wang TM, Chen CJ, Lee TS, Chao HY, Wu WH, Hsieh SC, Sheu HH, Chiang AN. Wang TM, et al. J Nutr Biochem. 2011 Feb;22(2):187-94. doi: 10.1016/j.jnutbio.2010.01.007. Epub 2010 Jun 22. J Nutr Biochem. 2011. PMID: 20573493

Sargachromenol protects against vascular inflammation by preventing TNF-α-induced monocyte adhesion to primary endothelial cells via inhibition of NF-κB activation.

Gwon WG, Joung EJ, Kwon MS, Lim SJ, Utsuki T, Kim HR. Gwon WG, et al. Int Immunopharmacol. 2017 Jan;42:81-89. doi: 10.1016/j.intimp.2016.11.014. Epub 2016 Nov 27. Int Immunopharmacol. 2017. PMID: 27902962

Natural Compound Resveratrol Attenuates TNF-Alpha-Induced Vascular Dysfunction in Mice and Human Endothelial Cells: The Involvement of the NF-κB Signaling Pathway.

Nallasamy P, Kang ZY, Sun X, Anandh Babu PV, Liu D, Jia Z. Nallasamy P, et al. Int J Mol Sci. 2021 Nov 19;22(22):12486. doi: 10.3390/ijms222212486. Int J Mol Sci. 2021. PMID: 34830366 Free PMC article.

Inhibitory effect of Malvidin on TNF-α-induced inflammatory response in endothelial cells.

Huang WY, Wang J, Liu YM, Zheng QS, Li CY. Huang WY, et al. Eur J Pharmacol. 2014 Jan 15;723:67-72. doi: 10.1016/j.ejphar.2013.11.041. Epub 2013 Dec 11. Eur J Pharmacol. 2014. PMID: 24333549

Clematichinenoside inhibits VCAM-1 and ICAM-1 expression in TNF-α-treated endothelial cells via NADPH oxidase-dependent IκB kinase/NF-κB pathway.

Yan S, Zhang X, Zheng H, Hu D, Zhang Y, Guan Q, Liu L, Ding Q, Li Y. Yan S, et al. Free Radic Biol Med. 2015 Jan;78:190-201. doi: 10.1016/j.freeradbiomed.2014.11.004. Epub 2014 Nov 13. Free Radic Biol Med. 2015. PMID: 25463279

Genistein inhibits TNF-α-induced endothelial inflammation through the protein kinase pathway A and improves vascular inflammation in C57BL/6 mice.

Jia Z, Babu PV, Si H, Nallasamy P, Zhu H, Zhen W, Misra HP, Li Y, Liu D. Jia Z, et al. Int J Cardiol. 2013 Oct 3;168(3):2637-45. doi: 10.1016/j.ijcard.2013.03.035. Epub 2013 Apr 12. Int J Cardiol. 2013. PMID: 23587398 Free PMC article.

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