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Items: 1 to 20 of 110

1.

Retinoid X receptors orchestrate osteoclast differentiation and postnatal bone remodeling.

Menéndez-Gutiérrez MP, Rőszer T, Fuentes L, Núñez V, Escolano A, Redondo JM, De Clerck N, Metzger D, Valledor AF, Ricote M.

J Clin Invest. 2015 Feb;125(2):809-23. doi: 10.1172/JCI77186. Epub 2015 Jan 9.

2.

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling.

Yoshikawa T, Ide T, Shimano H, Yahagi N, Amemiya-Kudo M, Matsuzaka T, Yatoh S, Kitamine T, Okazaki H, Tamura Y, Sekiya M, Takahashi A, Hasty AH, Sato R, Sone H, Osuga J, Ishibashi S, Yamada N.

Mol Endocrinol. 2003 Jul;17(7):1240-54. Epub 2003 May 1.

PMID:
12730331
3.

The multi-faceted role of retinoid X receptor in bone remodeling.

Menéndez-Gutiérrez MP, Ricote M.

Cell Mol Life Sci. 2017 Jun;74(12):2135-2149. doi: 10.1007/s00018-017-2458-4. Epub 2017 Jan 19. Review.

PMID:
28105491
4.

Structure basis of bigelovin as a selective RXR agonist with a distinct binding mode.

Zhang H, Li L, Chen L, Hu L, Jiang H, Shen X.

J Mol Biol. 2011 Mar 18;407(1):13-20. doi: 10.1016/j.jmb.2011.01.032. Epub 2011 Jan 22.

PMID:
21262235
5.

Genome-wide profiling of liver X receptor, retinoid X receptor, and peroxisome proliferator-activated receptor α in mouse liver reveals extensive sharing of binding sites.

Boergesen M, Pedersen TÅ, Gross B, van Heeringen SJ, Hagenbeek D, Bindesbøll C, Caron S, Lalloyer F, Steffensen KR, Nebb HI, Gustafsson JÅ, Stunnenberg HG, Staels B, Mandrup S.

Mol Cell Biol. 2012 Feb;32(4):852-67. doi: 10.1128/MCB.06175-11. Epub 2011 Dec 12.

6.

Tributyltin induces distinct effects on cortical and trabecular bone in female C57Bl/6J mice.

Watt J, Baker AH, Meeks B, Pajevic PD, Morgan EF, Gerstenfeld LC, Schlezinger JJ.

J Cell Physiol. 2018 Sep;233(9):7007-7021. doi: 10.1002/jcp.26495. Epub 2018 Mar 25.

PMID:
29380368
7.

MafB negatively regulates RANKL-mediated osteoclast differentiation.

Kim K, Kim JH, Lee J, Jin HM, Kook H, Kim KK, Lee SY, Kim N.

Blood. 2007 Apr 15;109(8):3253-9. Epub 2006 Dec 7.

PMID:
17158225
8.

Molecular determinants of the interactions between SRC-1 and LXR/RXR heterodimers.

Son YL, Lee YC.

FEBS Lett. 2010 Sep 24;584(18):3862-6. doi: 10.1016/j.febslet.2010.07.056. Epub 2010 Aug 1.

9.

Activation of liver X receptor (LXR) inhibits receptor activator of nuclear factor κB ligand (RANKL)-induced osteoclast differentiation in an LXRβ-dependent mechanism.

Remen KM, Henning P, Lerner UH, Gustafsson JÅ, Andersson G.

J Biol Chem. 2011 Sep 23;286(38):33084-94. doi: 10.1074/jbc.M111.235937. Epub 2011 Jul 22.

10.

Suppression of the pancreatic duodenal homeodomain transcription factor-1 (Pdx-1) promoter by sterol regulatory element-binding protein-1c (SREBP-1c).

Amemiya-Kudo M, Oka J, Takeuchi Y, Okazaki H, Yamamoto T, Yahagi N, Matsuzaka K, Okazaki S, Osuga J, Yamada N, Murase T, Shimano H.

J Biol Chem. 2011 Aug 12;286(32):27902-14. doi: 10.1074/jbc.M110.186221. Epub 2011 Jun 7.

11.

Crosstalk between RXR, LXR and VDR within blood mononuclear cellular model.

Dave VP, Kaul D, Sharma M.

Indian J Exp Biol. 2012 Jan;50(1):35-40.

PMID:
22279938
12.

MafB promotes atherosclerosis by inhibiting foam-cell apoptosis.

Hamada M, Nakamura M, Tran MT, Moriguchi T, Hong C, Ohsumi T, Dinh TT, Kusakabe M, Hattori M, Katsumata T, Arai S, Nakashima K, Kudo T, Kuroda E, Wu CH, Kao PH, Sakai M, Shimano H, Miyazaki T, Tontonoz P, Takahashi S.

Nat Commun. 2014;5:3147. doi: 10.1038/ncomms4147.

PMID:
24445679
13.

Inhibition of Ca²⁺/calmodulin-dependent protein kinase kinase 2 stimulates osteoblast formation and inhibits osteoclast differentiation.

Cary RL, Waddell S, Racioppi L, Long F, Novack DV, Voor MJ, Sankar U.

J Bone Miner Res. 2013 Jul;28(7):1599-610. doi: 10.1002/jbmr.1890.

14.

FoxO1 inhibits sterol regulatory element-binding protein-1c (SREBP-1c) gene expression via transcription factors Sp1 and SREBP-1c.

Deng X, Zhang W, O-Sullivan I, Williams JB, Dong Q, Park EA, Raghow R, Unterman TG, Elam MB.

J Biol Chem. 2012 Jun 8;287(24):20132-43. doi: 10.1074/jbc.M112.347211. Epub 2012 Apr 16.

15.

Liver X receptors orchestrate osteoblast/osteoclast crosstalk and counteract pathologic bone loss.

Kleyer A, Scholtysek C, Bottesch E, Hillienhof U, Beyer C, Distler JH, Tuckermann JP, Schett G, Krönke G.

J Bone Miner Res. 2012 Dec;27(12):2442-51. doi: 10.1002/jbmr.1702.

16.

Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter.

Yoshikawa T, Shimano H, Amemiya-Kudo M, Yahagi N, Hasty AH, Matsuzaka T, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Harada K, Gotoda T, Kimura S, Ishibashi S, Yamada N.

Mol Cell Biol. 2001 May;21(9):2991-3000.

17.

The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis.

Miyauchi Y, Ninomiya K, Miyamoto H, Sakamoto A, Iwasaki R, Hoshi H, Miyamoto K, Hao W, Yoshida S, Morioka H, Chiba K, Kato S, Tokuhisa T, Saitou M, Toyama Y, Suda T, Miyamoto T.

J Exp Med. 2010 Apr 12;207(4):751-62. doi: 10.1084/jem.20091957. Epub 2010 Apr 5.

18.

Liver X receptor activation inhibits osteoclastogenesis by suppressing NF-κB activity and c-Fos induction and prevents inflammatory bone loss in mice.

Kim HJ, Yoon KA, Yoon HJ, Hong JM, Lee MJ, Lee IK, Kim SY.

J Leukoc Biol. 2013 Jul;94(1):99-107. doi: 10.1189/jlb.1112601. Epub 2013 May 8.

PMID:
23657115
19.

Modulation of RXR function through ligand design.

Pérez E, Bourguet W, Gronemeyer H, de Lera AR.

Biochim Biophys Acta. 2012 Jan;1821(1):57-69. doi: 10.1016/j.bbalip.2011.04.003. Epub 2011 Apr 16. Review.

PMID:
21515403
20.

Thyroid hormone-responsive SPOT 14 homolog promotes hepatic lipogenesis, and its expression is regulated by liver X receptor α through a sterol regulatory element-binding protein 1c-dependent mechanism in mice.

Wu J, Wang C, Li S, Li S, Wang W, Li J, Chi Y, Yang H, Kong X, Zhou Y, Dong C, Wang F, Xu G, Yang J, Gustafsson JÅ, Guan Y.

Hepatology. 2013 Aug;58(2):617-28. doi: 10.1002/hep.26272. Epub 2013 Jul 2.

PMID:
23348573

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