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Items: 1 to 20 of 100

1.

Novel genes for airway wall thickness identified with combined genome-wide association and expression analyses.

Dijkstra AE, Postma DS, van Ginneken B, Wielpütz MO, Schmidt M, Becker N, Owsijewitsch M, Kauczor HU, de Koning HJ, Lammers JW, Oudkerk M, Brandsma CA, Bossé Y, Nickle DC, Sin DD, Hiemstra PS, Wijmenga C, Smolonska J, Zanen P, Vonk JM, van den Berge M, Boezen HM, Groen HJ.

Am J Respir Crit Care Med. 2015 Mar 1;191(5):547-56. doi: 10.1164/rccm.201405-0840OC.

PMID:
25517131
2.

A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes.

Cho MH, Castaldi PJ, Hersh CP, Hobbs BD, Barr RG, Tal-Singer R, Bakke P, Gulsvik A, San José Estépar R, Van Beek EJ, Coxson HO, Lynch DA, Washko GR, Laird NM, Crapo JD, Beaty TH, Silverman EK; NETT Genetics, ECLIPSE, and COPDGene Investigators.

Am J Respir Crit Care Med. 2015 Sep 1;192(5):559-69. doi: 10.1164/rccm.201501-0148OC.

3.

Visual Assessment of Chest Computed Tomographic Images Is Independently Useful for Genetic Association Analysis in Studies of Chronic Obstructive Pulmonary Disease.

Halper-Stromberg E, Cho MH, Wilson C, Nevrekar D, Crapo JD, Washko G, Estépar RS, Lynch DA, Silverman EK, Leach S, Castaldi PJ.

Ann Am Thorac Soc. 2017 Jan;14(1):33-40. doi: 10.1513/AnnalsATS.201606-427OC.

4.

Association of COPD candidate genes with computed tomography emphysema and airway phenotypes in severe COPD.

Kim WJ, Hoffman E, Reilly J, Hersh C, Demeo D, Washko G, Silverman EK.

Eur Respir J. 2011 Jan;37(1):39-43. doi: 10.1183/09031936.00173009. Epub 2010 Jun 4.

5.

SERPINE2 haplotype as a risk factor for panlobular type of emphysema.

Kukkonen MK, Tiili E, Hämäläinen S, Vehmas T, Oksa P, Piirilä P, Hirvonen A.

BMC Med Genet. 2011 Dec 7;12:157. doi: 10.1186/1471-2350-12-157.

6.

Airway wall thickening and emphysema show independent familial aggregation in chronic obstructive pulmonary disease.

Patel BD, Coxson HO, Pillai SG, Agustí AG, Calverley PM, Donner CF, Make BJ, Müller NL, Rennard SI, Vestbo J, Wouters EF, Hiorns MP, Nakano Y, Camp PG, Nasute Fauerbach PV, Screaton NJ, Campbell EJ, Anderson WH, Paré PD, Levy RD, Lake SL, Silverman EK, Lomas DA; International COPD Genetics Network.

Am J Respir Crit Care Med. 2008 Sep 1;178(5):500-5. doi: 10.1164/rccm.200801-059OC. Epub 2008 Jun 19.

PMID:
18565956
7.

The 15q24/25 susceptibility variant for lung cancer and chronic obstructive pulmonary disease is associated with emphysema.

Lambrechts D, Buysschaert I, Zanen P, Coolen J, Lays N, Cuppens H, Groen HJ, Dewever W, van Klaveren RJ, Verschakelen J, Wijmenga C, Postma DS, Decramer M, Janssens W.

Am J Respir Crit Care Med. 2010 Mar 1;181(5):486-93. doi: 10.1164/rccm.200909-1364OC. Epub 2009 Dec 10.

PMID:
20007924
8.

Low-dose CT measurements of airway dimensions and emphysema associated with airflow limitation in heavy smokers: a cross sectional study.

Dijkstra AE, Postma DS, ten Hacken N, Vonk JM, Oudkerk M, van Ooijen PM, Zanen P, Mohamed Hoesein FA, van Ginneken B, Schmidt M, Groen HJ.

Respir Res. 2013 Jan 28;14:11. doi: 10.1186/1465-9921-14-11.

9.

Limited overlap in significant hits between genome-wide association studies on two airflow obstruction definitions in the same population.

van der Plaat DA, Vonk JM, Lahousse L, de Jong K, Faiz A, Nedeljkovic I, Amin N, van Diemen CC, Brusselle GG, Bossé Y, Brandsma CA, Hao K, Paré PD, van Duijn CM, Postma DS, Boezen HM.

BMC Pulm Med. 2019 Mar 7;19(1):58. doi: 10.1186/s12890-019-0811-0.

10.

Two CHRN susceptibility variants for COPD are genetic determinants of emphysema and chest computed tomography manifestations in Chinese patients.

Zhao Z, Jiang C, Zhao D, Li Y, Liang C, Liu W, Wei S, Zhou Y, Zhao Z, Ran P.

Int J Chron Obstruct Pulmon Dis. 2017 May 15;12:1447-1455. doi: 10.2147/COPD.S134010. eCollection 2017.

11.

A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.

Pillai SG, Ge D, Zhu G, Kong X, Shianna KV, Need AC, Feng S, Hersh CP, Bakke P, Gulsvik A, Ruppert A, Lødrup Carlsen KC, Roses A, Anderson W, Rennard SI, Lomas DA, Silverman EK, Goldstein DB; ICGN Investigators.

PLoS Genet. 2009 Mar;5(3):e1000421. doi: 10.1371/journal.pgen.1000421. Epub 2009 Mar 20.

12.

The Relationship of Educational Attainment with Pulmonary Emphysema and Airway Wall Thickness.

Gjerdevik M, Grydeland TB, Washko GR, Coxson HO, Silverman EK, Gulsvik A, Bakke PS.

Ann Am Thorac Soc. 2015 Jun;12(6):813-20. doi: 10.1513/AnnalsATS.201410-485OC.

PMID:
25822654
13.

Loci identified by genome-wide association studies influence different disease-related phenotypes in chronic obstructive pulmonary disease.

Pillai SG, Kong X, Edwards LD, Cho MH, Anderson WH, Coxson HO, Lomas DA, Silverman EK; ECLIPSE and ICGN Investigators.

Am J Respir Crit Care Med. 2010 Dec 15;182(12):1498-505. doi: 10.1164/rccm.201002-0151OC. Epub 2010 Jul 23.

14.

Genome-wide association identifies regulatory Loci associated with distinct local histogram emphysema patterns.

Castaldi PJ, Cho MH, San José Estépar R, McDonald ML, Laird N, Beaty TH, Washko G, Crapo JD, Silverman EK; COPDGene Investigators.

Am J Respir Crit Care Med. 2014 Aug 15;190(4):399-409. doi: 10.1164/rccm.201403-0569OC.

15.

Polymorphisms in the superoxide dismutase-3 gene are associated with emphysema in COPD.

Sørheim IC, DeMeo DL, Washko G, Litonjua A, Sparrow D, Bowler R, Bakke P, Pillai SG, Coxson HO, Lomas DA, Silverman EK, Hersh CP; International COPD Genetics Network Investigators.

COPD. 2010 Aug;7(4):262-8. doi: 10.3109/15412555.2010.496821.

16.

Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene.

Hersh CP, Pillai SG, Zhu G, Lomas DA, Bakke P, Gulsvik A, DeMeo DL, Klanderman BJ, Lazarus R, Litonjua AA, Sparrow D, Reilly JJ, Agusti A, Calverley PM, Donner CF, Levy RD, Make BJ, Paré PD, Rennard SI, Vestbo J, Wouters EF, Scholand MB, Coon H, Hoidal J, Silverman EK.

Am J Respir Crit Care Med. 2010 Sep 1;182(5):605-13. doi: 10.1164/rccm.200910-1586OC. Epub 2010 May 12.

17.

Genome-wide association study on the FEV1/FVC ratio in never-smokers identifies HHIP and FAM13A.

van der Plaat DA, de Jong K, Lahousse L, Faiz A, Vonk JM, van Diemen CC, Nedeljkovic I, Amin N, Brusselle GG, Hofman A, Brandsma CA, Bossé Y, Sin DD, Nickle DC, van Duijn CM, Postma DS, Boezen HM.

J Allergy Clin Immunol. 2017 Feb;139(2):533-540. doi: 10.1016/j.jaci.2016.06.062. Epub 2016 Sep 6.

PMID:
27612410
18.

Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema.

Kong X, Cho MH, Anderson W, Coxson HO, Muller N, Washko G, Hoffman EA, Bakke P, Gulsvik A, Lomas DA, Silverman EK, Pillai SG; ECLIPSE Study NETT Investigators.

Am J Respir Crit Care Med. 2011 Jan 1;183(1):43-9. doi: 10.1164/rccm.201004-0541OC. Epub 2010 Aug 13.

19.

Genome-Wide Association Study Identification of Novel Loci Associated with Airway Responsiveness in Chronic Obstructive Pulmonary Disease.

Hansel NN, Paré PD, Rafaels N, Sin DD, Sandford A, Daley D, Vergara C, Huang L, Elliott WM, Pascoe CD, Arsenault BA, Postma DS, Boezen HM, Bossé Y, van den Berge M, Hiemstra PS, Cho MH, Litonjua AA, Sparrow D, Ober C, Wise RA, Connett J, Neptune ER, Beaty TH, Ruczinski I, Mathias RA, Barnes KC; Lung Health Study.

Am J Respir Cell Mol Biol. 2015 Aug;53(2):226-34. doi: 10.1165/rcmb.2014-0198OC.

20.

Genome-Wide Association Study of the Genetic Determinants of Emphysema Distribution.

Boueiz A, Lutz SM, Cho MH, Hersh CP, Bowler RP, Washko GR, Halper-Stromberg E, Bakke P, Gulsvik A, Laird NM, Beaty TH, Coxson HO, Crapo JD, Silverman EK, Castaldi PJ, DeMeo DL; COPDGene and ECLIPSE Investigators.

Am J Respir Crit Care Med. 2017 Mar 15;195(6):757-771. doi: 10.1164/rccm.201605-0997OC.

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