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Items: 1 to 20 of 114

1.

Glycosaminoglycan binding by Borrelia burgdorferi adhesin BBK32 specifically and uniquely promotes joint colonization.

Lin YP, Chen Q, Ritchie JA, Dufour NP, Fischer JR, Coburn J, Leong JM.

Cell Microbiol. 2015 Jun;17(6):860-75. doi: 10.1111/cmi.12407. Epub 2015 Jan 24.

2.

Inactivation of the fibronectin-binding adhesin gene bbk32 significantly attenuates the infectivity potential of Borrelia burgdorferi.

Seshu J, Esteve-Gassent MD, Labandeira-Rey M, Kim JH, Trzeciakowski JP, Höök M, Skare JT.

Mol Microbiol. 2006 Mar;59(5):1591-601.

3.
4.

Bioluminescent imaging of Borrelia burgdorferi in vivo demonstrates that the fibronectin-binding protein BBK32 is required for optimal infectivity.

Hyde JA, Weening EH, Chang M, Trzeciakowski JP, Höök M, Cirillo JD, Skare JT.

Mol Microbiol. 2011 Oct;82(1):99-113. doi: 10.1111/j.1365-2958.2011.07801.x. Epub 2011 Aug 30.

5.

Borrelia burgdorferi lacking BBK32, a fibronectin-binding protein, retains full pathogenicity.

Li X, Liu X, Beck DS, Kantor FS, Fikrig E.

Infect Immun. 2006 Jun;74(6):3305-13.

6.

A short-term Borrelia burgdorferi infection model identifies tissue tropisms and bloodstream survival conferred by adhesion proteins.

Caine JA, Coburn J.

Infect Immun. 2015 Aug;83(8):3184-94. doi: 10.1128/IAI.00349-15. Epub 2015 May 26.

7.

The Borrelia burgdorferi Glycosaminoglycan Binding Protein Bgp in the B31 Strain Is Not Essential for Infectivity despite Facilitating Adherence and Tissue Colonization.

Schlachter S, Seshu J, Lin T, Norris S, Parveen N.

Infect Immun. 2018 Jan 22;86(2). pii: e00667-17. doi: 10.1128/IAI.00667-17. Print 2018 Feb.

8.

Decorin-binding proteins A and B confer distinct mammalian cell type-specific attachment by Borrelia burgdorferi, the Lyme disease spirochete.

Fischer JR, Parveen N, Magoun L, Leong JM.

Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7307-12. Epub 2003 May 28.

9.
10.

Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules.

Moriarty TJ, Shi M, Lin YP, Ebady R, Zhou H, Odisho T, Hardy PO, Salman-Dilgimen A, Wu J, Weening EH, Skare JT, Kubes P, Leong J, Chaconas G.

Mol Microbiol. 2012 Dec;86(5):1116-31. doi: 10.1111/mmi.12045. Epub 2012 Oct 24.

11.

Borrelia burgdorferi protein BBK32 binds to soluble fibronectin via the N-terminal 70-kDa region, causing fibronectin to undergo conformational extension.

Harris G, Ma W, Maurer LM, Potts JR, Mosher DF.

J Biol Chem. 2014 Aug 8;289(32):22490-9. doi: 10.1074/jbc.M114.578419. Epub 2014 Jun 24.

12.

BBK32, a fibronectin binding MSCRAMM from Borrelia burgdorferi, contains a disordered region that undergoes a conformational change on ligand binding.

Kim JH, Singvall J, Schwarz-Linek U, Johnson BJ, Potts JR, Höök M.

J Biol Chem. 2004 Oct 1;279(40):41706-14. Epub 2004 Jul 29.

13.
14.

Borrelia burgdorferi binds fibronectin through a tandem beta-zipper, a common mechanism of fibronectin binding in staphylococci, streptococci, and spirochetes.

Raibaud S, Schwarz-Linek U, Kim JH, Jenkins HT, Baines ER, Gurusiddappa S, Höök M, Potts JR.

J Biol Chem. 2005 May 13;280(19):18803-9. Epub 2005 Feb 28.

15.

Borrelia burgdorferi RevA antigen binds host fibronectin.

Brissette CA, Bykowski T, Cooley AE, Bowman A, Stevenson B.

Infect Immun. 2009 Jul;77(7):2802-12. doi: 10.1128/IAI.00227-09. Epub 2009 Apr 27.

16.

Strain-specific variation of the decorin-binding adhesin DbpA influences the tissue tropism of the lyme disease spirochete.

Lin YP, Benoit V, Yang X, Martínez-Herranz R, Pal U, Leong JM.

PLoS Pathog. 2014 Jul 31;10(7):e1004238. doi: 10.1371/journal.ppat.1004238. eCollection 2014 Jul.

17.

Regulation of expression of the fibronectin-binding protein BBK32 in Borrelia burgdorferi.

He M, Boardman BK, Yan D, Yang XF.

J Bacteriol. 2007 Nov;189(22):8377-80. Epub 2007 Sep 14.

18.

Mapping the ligand-binding region of Borrelia burgdorferi fibronectin-binding protein BBK32.

Probert WS, Kim JH, Höök M, Johnson BJ.

Infect Immun. 2001 Jun;69(6):4129-33.

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20.

Allelic variation of the Lyme disease spirochete adhesin DbpA influences spirochetal binding to decorin, dermatan sulfate, and mammalian cells.

Benoit VM, Fischer JR, Lin YP, Parveen N, Leong JM.

Infect Immun. 2011 Sep;79(9):3501-9. doi: 10.1128/IAI.00163-11. Epub 2011 Jun 27.

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