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Items: 1 to 20 of 111

1.

Increased levels of IL-6 in the cerebrospinal fluid of patients with chronic schizophrenia--significance for activation of the kynurenine pathway.

Schwieler L, Larsson MK, Skogh E, Kegel ME, Orhan F, Abdelmoaty S, Finn A, Bhat M, Samuelsson M, Lundberg K, Dahl ML, Sellgren C, Schuppe-Koistinen I, Svensson C, Erhardt S, Engberg G.

J Psychiatry Neurosci. 2015 Mar;40(2):126-33.

2.

Increased levels of kynurenine and kynurenic acid in the CSF of patients with schizophrenia.

Linderholm KR, Skogh E, Olsson SK, Dahl ML, Holtze M, Engberg G, Samuelsson M, Erhardt S.

Schizophr Bull. 2012 May;38(3):426-32. doi: 10.1093/schbul/sbq086. Epub 2010 Aug 20.

3.

Kynurenic acid and psychotic symptoms and personality traits in twins with psychiatric morbidity.

Kegel ME, Johansson V, Wetterberg L, Bhat M, Schwieler L, Cannon TD, Schuppe-Koistinen I, Engberg G, Landén M, Hultman CM, Erhardt S.

Psychiatry Res. 2017 Jan;247:105-112. doi: 10.1016/j.psychres.2016.11.017. Epub 2016 Nov 16.

PMID:
27886578
4.

Inhibition of Large Neutral Amino Acid Transporters Suppresses Kynurenic Acid Production Via Inhibition of Kynurenine Uptake in Rodent Brain.

Sekine A, Kuroki Y, Urata T, Mori N, Fukuwatari T.

Neurochem Res. 2016 Sep;41(9):2256-66. doi: 10.1007/s11064-016-1940-y. Epub 2016 May 9.

PMID:
27161376
5.

Activation of kynurenine pathway in ex vivo fibroblasts from patients with bipolar disorder or schizophrenia: cytokine challenge increases production of 3-hydroxykynurenine.

Johansson AS, Owe-Larsson B, Asp L, Kocki T, Adler M, Hetta J, Gardner R, Lundkvist GB, Urbanska EM, Karlsson H.

J Psychiatr Res. 2013 Nov;47(11):1815-23. doi: 10.1016/j.jpsychires.2013.08.008. Epub 2013 Aug 23.

PMID:
24012176
6.

The kynurenine pathway is involved in bacterial meningitis.

Coutinho LG, Christen S, Bellac CL, Fontes FL, Souza FR, Grandgirard D, Leib SL, Agnez-Lima LF.

J Neuroinflammation. 2014 Oct 2;11:169. doi: 10.1186/s12974-014-0169-4.

7.

Age-related increase of kynurenic acid in human cerebrospinal fluid - IgG and beta2-microglobulin changes.

Kepplinger B, Baran H, Kainz A, Ferraz-Leite H, Newcombe J, Kalina P.

Neurosignals. 2005;14(3):126-35.

8.

Electroconvulsive therapy suppresses the neurotoxic branch of the kynurenine pathway in treatment-resistant depressed patients.

Schwieler L, Samuelsson M, Frye MA, Bhat M, Schuppe-Koistinen I, Jungholm O, Johansson AG, Landén M, Sellgren CM, Erhardt S.

J Neuroinflammation. 2016 Feb 29;13(1):51. doi: 10.1186/s12974-016-0517-7.

9.

Imbalanced kynurenine pathway in schizophrenia.

Kegel ME, Bhat M, Skogh E, Samuelsson M, Lundberg K, Dahl ML, Sellgren C, Schwieler L, Engberg G, Schuppe-Koistinen I, Erhardt S.

Int J Tryptophan Res. 2014 Sep 16;7:15-22. doi: 10.4137/IJTR.S16800. eCollection 2014.

10.

Increased Levels of Kynurenic Acid in the Cerebrospinal Fluid in Patients with Hydrocephalus.

Kepplinger B, Baran H, Kronsteiner C, Reuss J.

Neurosignals. 2019;27(1):1-11. doi: 10.33594/000000095.

11.
12.

Elevated levels of kynurenic acid in the cerebrospinal fluid of male patients with schizophrenia.

Nilsson LK, Linderholm KR, Engberg G, Paulson L, Blennow K, Lindström LH, Nordin C, Karanti A, Persson P, Erhardt S.

Schizophr Res. 2005 Dec 15;80(2-3):315-22. Epub 2005 Aug 25.

PMID:
16125901
13.

Kynurenic Acid in Schizophrenia: A Systematic Review and Meta-analysis.

Plitman E, Iwata Y, Caravaggio F, Nakajima S, Chung JK, Gerretsen P, Kim J, Takeuchi H, Chakravarty MM, Remington G, Graff-Guerrero A.

Schizophr Bull. 2017 Jul 1;43(4):764-777. doi: 10.1093/schbul/sbw221. Review.

14.

Correlations of Kynurenic Acid, 3-Hydroxykynurenine, sIL-2R, IFN-α, and IL-4 with Clinical Symptoms During Acute Relapse of Schizophrenia.

Szymona K, Zdzisińska B, Karakuła-Juchnowicz H, Kocki T, Kandefer-Szerszeń M, Flis M, Rosa W, Urbańska EM.

Neurotox Res. 2017 Jul;32(1):17-26. doi: 10.1007/s12640-017-9714-0. Epub 2017 Mar 8.

PMID:
28275903
15.

Schizophrenia as an inflammation-mediated dysbalance of glutamatergic neurotransmission.

Muller N, Schwarz M.

Neurotox Res. 2006 Oct;10(2):131-48. Review.

PMID:
17062375
16.

Dysregulation of kynurenine metabolism is related to proinflammatory cytokines, attention, and prefrontal cortex volume in schizophrenia.

Kindler J, Lim CK, Weickert CS, Boerrigter D, Galletly C, Liu D, Jacobs KR, Balzan R, Bruggemann J, O'Donnell M, Lenroot R, Guillemin GJ, Weickert TW.

Mol Psychiatry. 2019 Apr 3. doi: 10.1038/s41380-019-0401-9. [Epub ahead of print]

PMID:
30940904
17.

Modulation by kynurenine of extracellular kynurenate and glutamate in cerebral cortex of rats with acute liver failure.

Hilgier W, Kocki T, Obara-Michlewska M, Turski WA, Oja SS, Saransaari P, Albrecht J.

Pharmacol Rep. 2014 Jun;66(3):466-70. doi: 10.1016/j.pharep.2013.11.007. Epub 2014 Apr 13.

PMID:
24905525
18.

Cerebrospinal fluid kynurenine and kynurenic acid concentrations are associated with coma duration and long-term neurocognitive impairment in Ugandan children with cerebral malaria.

Holmberg D, Franzén-Röhl E, Idro R, Opoka RO, Bangirana P, Sellgren CM, Wickström R, Färnert A, Schwieler L, Engberg G, John CC.

Malar J. 2017 Jul 28;16(1):303. doi: 10.1186/s12936-017-1954-1.

19.

The KMO allele encoding Arg452 is associated with psychotic features in bipolar disorder type 1, and with increased CSF KYNA level and reduced KMO expression.

Lavebratt C, Olsson S, Backlund L, Frisén L, Sellgren C, Priebe L, Nikamo P, Träskman-Bendz L, Cichon S, Vawter MP, Osby U, Engberg G, Landén M, Erhardt S, Schalling M.

Mol Psychiatry. 2014 Mar;19(3):334-41. doi: 10.1038/mp.2013.11. Epub 2013 Mar 5.

20.

Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans.

Yan EB, Frugier T, Lim CK, Heng B, Sundaram G, Tan M, Rosenfeld JV, Walker DW, Guillemin GJ, Morganti-Kossmann MC.

J Neuroinflammation. 2015 May 30;12:110. doi: 10.1186/s12974-015-0328-2.

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