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Examining the polymorphisms in the hypoxia pathway genes in relation to outcome in colorectal cancer.

Haja Mohideen AM, Hyde A, Squires J, Wang J, Dicks E, Younghusband B, Parfrey P, Green R, Savas S.

PLoS One. 2014 Nov 18;9(11):e113513. doi: 10.1371/journal.pone.0113513. eCollection 2014.


Progesterone and interferon tau regulate hypoxia-inducible factors in the endometrium of the ovine uterus.

Song G, Kim J, Bazer FW, Spencer TE.

Endocrinology. 2008 Apr;149(4):1926-34. doi: 10.1210/en.2007-1530. Epub 2008 Jan 3.


Functional polymorphisms of circadian positive feedback regulation genes and clinical outcome of Chinese patients with resected colorectal cancer.

Zhou F, He X, Liu H, Zhu Y, Jin T, Chen C, Qu F, Li Y, Bao G, Chen Z, Xing J.

Cancer. 2012 Feb 15;118(4):937-46. doi: 10.1002/cncr.26348. Epub 2011 Jul 19.


Association of hypoxia-inducible factor 1-alpha gene polymorphisms and colorectal cancer prognosis.

Szkandera J, Knechtel G, Stotz M, Hofmann G, Langsenlehner U, Krippl P, Langsenlehner T, Dehchamani D, Samonigg H, Renner W, Gerger A.

Anticancer Res. 2010 Jun;30(6):2393-7.


No association of the hypoxia-inducible factor-1α gene polymorphisms with survival in patients with colorectal cancer.

Lee SJ, Kim JG, Sohn SK, Chae YS, Moon JH, Kang BW, Park JS, Park JY, Choi GS.

Med Oncol. 2011 Dec;28(4):1032-7. doi: 10.1007/s12032-010-9618-9. Epub 2010 Jul 16.


Hypoxia and renal cell carcinoma: The influence of HIF1A+1772C/T functional genetic polymorphism on prognosis.

Ferreira M, Teixeira A, Maurício J, Lobo F, Morais A, Medeiros R.

Urol Oncol. 2017 Aug;35(8):532.e25-532.e30. doi: 10.1016/j.urolonc.2017.04.002. Epub 2017 May 2.


Polymorphisms of HIF1A gene are associated with prognosis of early stage non-small-cell lung cancer patients after surgery.

Liu B, Liu Q, Song Y, Li X, Wang Y, Wan S, Zhang Z, Su H.

Med Oncol. 2014 Apr;31(4):877. doi: 10.1007/s12032-014-0877-8. Epub 2014 Feb 25.


The polymorphisms in the VHL and HIF1A genes are associated with the prognosis but not the development of renal cell carcinoma.

Qin C, Cao Q, Ju X, Wang M, Meng X, Zhu J, Yan F, Li P, Ding Q, Chen J, Gu M, Zhang W, Yin C, Zhang Z.

Ann Oncol. 2012 Apr;23(4):981-9. doi: 10.1093/annonc/mdr325. Epub 2011 Jul 21.


Single nucleotide polymorphisms within interferon signaling pathway genes are associated with colorectal cancer susceptibility and survival.

Lu S, Pardini B, Cheng B, Naccarati A, Huhn S, Vymetalkova V, Vodickova L, Buchler T, Hemminki K, Vodicka P, Försti A.

PLoS One. 2014 Oct 28;9(10):e111061. doi: 10.1371/journal.pone.0111061. eCollection 2014.


No associations of a set of SNPs in the Vascular Endothelial Growth Factor (VEGF) and Matrix Metalloproteinase (MMP) genes with survival of colorectal cancer patients.

Dan LA, Werdyani S, Xu J, Shestopaloff K, Hyde A, Dicks E, Younghusband B, Green J, Parfrey P, Xu W, Savas S.

Cancer Med. 2016 Sep;5(9):2221-31. doi: 10.1002/cam4.796. Epub 2016 Jun 23.


Genetic variations in the HIF1A gene modulate response to adjuvant chemotherapy after surgery in patients with colorectal cancer.

Zhang Y, Wang P, Zhou XC, Bao GQ, Lyu ZM, Liu XN, Wan SG, He XL, Huang QC.

Asian Pac J Cancer Prev. 2014;15(11):4637-42.


Genetic variations in STK11, PRKAA1, and TSC1 associated with prognosis for patients with colorectal cancer.

Lee SJ, Kang BW, Chae YS, Kim HJ, Park SY, Park JS, Choi GS, Jeon HS, Lee WK, Kim JG.

Ann Surg Oncol. 2014 Dec;21 Suppl 4:S634-9. doi: 10.1245/s10434-014-3729-z. Epub 2014 Apr 28.


Genetic variants in the vitamin D pathway and breast cancer disease-free survival.

Pande M, Thompson PA, Do KA, Sahin AA, Amos CI, Frazier ML, Bondy ML, Brewster AM.

Carcinogenesis. 2013 Mar;34(3):587-94. doi: 10.1093/carcin/bgs369. Epub 2012 Nov 24.


A Survival Association Study of 102 Polymorphisms Previously Associated with Survival Outcomes in Colorectal Cancer.

Savas S, Xu J, Werdyani S, Shestopaloff K, Dicks E, Green J, Parfrey P, Green R, Xu W.

Biomed Res Int. 2015;2015:968743. doi: 10.1155/2015/968743. Epub 2015 May 12.


Hypoxia-inducible transcription factors, HIF1A and HIF2A, increase in aging mucosal tissues.

Ebersole JL, Novak MJ, Orraca L, Martinez-Gonzalez J, Kirakodu S, Chen KC, Stromberg A, Gonzalez OA.

Immunology. 2018 Jul;154(3):452-464. doi: 10.1111/imm.12894. Epub 2018 Feb 14.


Hypoxia Inducible Factor-2 Alpha and Prolinhydroxylase 2 Polymorphisms in Patients with Acute Respiratory Distress Syndrome (ARDS).

Dötsch A, Eisele L, Rabeling M, Rump K, Walstein K, Bick A, Cox L, Engler A, Bachmann HS, Jöckel KH, Adamzik M, Peters J, Schäfer ST.

Int J Mol Sci. 2017 Jun 14;18(6). pii: E1266. doi: 10.3390/ijms18061266.


Stromal expression of hypoxia regulated proteins is an adverse prognostic factor in colorectal carcinomas.

Cleven AH, van Engeland M, Wouters BG, de Bruïne AP.

Cell Oncol. 2007;29(3):229-40.


Single nucleotide polymorphisms in the hypoxia-inducible factor-1 gene and colorectal cancer risk.

Knechtel G, Szkandera J, Stotz M, Hofmann G, Langsenlehner U, Krippl P, Samonigg H, Renner W, Langner C, Dehchamani D, Gerger A.

Mol Carcinog. 2010 Sep;49(9):805-9. doi: 10.1002/mc.20655.


Polymorphisms of genes involved in the hypoxia signaling pathway and the development of abdominal aortic aneurysms or large-artery atherosclerosis.

Strauss E, Waliszewski K, Oszkinis G, Staniszewski R.

J Vasc Surg. 2015 May;61(5):1105-13.e3. doi: 10.1016/j.jvs.2014.02.007. Epub 2014 Mar 20.


GATA2 rs2335052 Polymorphism Predicts the Survival of Patients with Colorectal Cancer.

Liu X, Jiang B, Wang A, Di J, Wang Z, Chen L, Su X.

PLoS One. 2015 Aug 19;10(8):e0136020. doi: 10.1371/journal.pone.0136020. eCollection 2015.

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