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Items: 1 to 20 of 335

1.

A signal integration model of thymic selection and natural regulatory T cell commitment.

Khailaie S, Robert PA, Toker A, Huehn J, Meyer-Hermann M.

J Immunol. 2014 Dec 15;193(12):5983-96. doi: 10.4049/jimmunol.1400889. Epub 2014 Nov 12.

2.

Alterations in the Thymic Selection Threshold Skew the Self-Reactivity of the TCR Repertoire in Neonates.

Dong M, Artusa P, Kelly SA, Fournier M, Baldwin TA, Mandl JN, Melichar HJ.

J Immunol. 2017 Aug 1;199(3):965-973. doi: 10.4049/jimmunol.1602137. Epub 2017 Jun 28.

4.

Role of thymic cortex-specific self-peptides in positive selection of T cells.

Takahama Y, Nitta T, Mat Ripen A, Nitta S, Murata S, Tanaka K.

Semin Immunol. 2010 Oct;22(5):287-93. doi: 10.1016/j.smim.2010.04.012. Epub 2010 May 26. Review.

PMID:
20510627
5.

Stable interactions and sustained TCR signaling characterize thymocyte-thymocyte interactions that support negative selection.

Melichar HJ, Ross JO, Taylor KT, Robey EA.

J Immunol. 2015 Feb 1;194(3):1057-1061. doi: 10.4049/jimmunol.1400169. Epub 2014 Dec 17.

6.

Thymic microenvironments for T-cell repertoire formation.

Nitta T, Murata S, Ueno T, Tanaka K, Takahama Y.

Adv Immunol. 2008;99:59-94. doi: 10.1016/S0065-2776(08)00603-2. Review.

PMID:
19117532
7.

Thymic selection generates T cells expressing self-reactive TCRs in the absence of CD45.

Trop S, Charron J, Arguin C, Lesage S, Hugo P.

J Immunol. 2000 Sep 15;165(6):3073-9. Erratum in: J Immunol 2000 Nov 1;165(9):following 5366.

8.

Distinct temporal patterns of T cell receptor signaling during positive versus negative selection in situ.

Melichar HJ, Ross JO, Herzmark P, Hogquist KA, Robey EA.

Sci Signal. 2013 Oct 15;6(297):ra92. doi: 10.1126/scisignal.2004400.

9.

Peptide specificity of thymic selection of CD4+CD25+ T cells.

Pacholczyk R, Kraj P, Ignatowicz L.

J Immunol. 2002 Jan 15;168(2):613-20.

10.
11.

Indirect presentation in the thymus limits naive and regulatory T-cell differentiation by promoting deletion of self-reactive thymocytes.

Yap JY, Wirasinha RC, Chan A, Howard DR, Goodnow CC, Daley SR.

Immunology. 2018 Jul;154(3):522-532. doi: 10.1111/imm.12904. Epub 2018 Feb 27.

12.

TCR engagement of CD4+CD8+ thymocytes in vitro induces early aspects of positive selection, but not apoptosis.

Groves T, Parsons M, Miyamoto NG, Guidos CJ.

J Immunol. 1997 Jan 1;158(1):65-75.

PMID:
8977176
14.

TCR tuning of T cell subsets.

Cho JH, Sprent J.

Immunol Rev. 2018 May;283(1):129-137. doi: 10.1111/imr.12646. Review.

PMID:
29664578
15.

Strength of TCR signal from self-peptide modulates autoreactive thymocyte deletion and Foxp3(+) Treg-cell formation.

Caton AJ, Kropf E, Simons DM, Aitken M, Weissler KA, Jordan MS.

Eur J Immunol. 2014 Mar;44(3):785-93. doi: 10.1002/eji.201343767. Epub 2013 Dec 27.

17.

Thymic selection by a single MHC/peptide ligand produces a semidiverse repertoire of CD4+ T cells.

Surh CD, Lee DS, Fung-Leung WP, Karlsson L, Sprent J.

Immunity. 1997 Aug;7(2):209-19.

18.

How nonuniform contact profiles of T cell receptors modulate thymic selection outcomes.

Chen H, Chakraborty AK, Kardar M.

Phys Rev E. 2018 Mar;97(3-1):032413. doi: 10.1103/PhysRevE.97.032413.

PMID:
29776088
19.
20.

Degree of TCR internalization and Ca2+ flux correlates with thymocyte selection.

Mariathasan S, Bachmann MF, Bouchard D, Ohteki T, Ohashi PS.

J Immunol. 1998 Dec 1;161(11):6030-7.

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