Similar articles for PMID: 25376372

Year	Number of Results
1991	2
1992	2
1995	3
1996	1
1998	2
2000	1
2001	3
2002	1
2004	1
2005	4
2006	2
2007	2
2008	7
2009	4
2010	3
2011	7
2012	6
2013	5
2014	5
2015	8
2016	11
2017	8
2018	9
2019	9
2020	8
2021	17
2022	19
2023	9
2024	0

1

Pharmacokinetic-pharmacodynamic modeling for reduction of hepatic apolipoprotein B mRNA and plasma total cholesterol after administration of antisense oligonucleotide in mice.

Shimizu R, Kitade M, Kobayashi T, Hori S, Watanabe A. Shimizu R, et al. J Pharmacokinet Pharmacodyn. 2015 Feb;42(1):67-77. doi: 10.1007/s10928-014-9398-5. Epub 2014 Nov 7. J Pharmacokinet Pharmacodyn. 2015. PMID: 25376372

2

Pharmacokinetic-pharmacodynamic modeling for hepatic delivery and efficacy of antisense oligonucleotides with lipophilic ligands in mice.

Watanabe A, Katsube T. Watanabe A, et al. Biopharm Drug Dispos. 2021 Apr;42(4):178-187. doi: 10.1002/bdd.2271. Epub 2021 Apr 28. Biopharm Drug Dispos. 2021. PMID: 33724506

3

Comparative Characterization of Hepatic Distribution and mRNA Reduction of Antisense Oligonucleotides Conjugated with Triantennary N-Acetyl Galactosamine and Lipophilic Ligands Targeting Apolipoprotein B.

Watanabe A, Nakajima M, Kasuya T, Onishi R, Kitade N, Mayumi K, Ikehara T, Kugimiya A. Watanabe A, et al. J Pharmacol Exp Ther. 2016 May;357(2):320-30. doi: 10.1124/jpet.115.230300. Epub 2016 Feb 23. J Pharmacol Exp Ther. 2016. PMID: 26907624

4

Cross-species comparison of in vivo PK/PD relationships for second-generation antisense oligonucleotides targeting apolipoprotein B-100.

Yu RZ, Lemonidis KM, Graham MJ, Matson JE, Crooke RM, Tribble DL, Wedel MK, Levin AA, Geary RS. Yu RZ, et al. Biochem Pharmacol. 2009 Mar 1;77(5):910-9. doi: 10.1016/j.bcp.2008.11.005. Epub 2008 Nov 14. Biochem Pharmacol. 2009. PMID: 19056355

5

Evaluation of the effects of chemically different linkers on hepatic accumulations, cell tropism and gene silencing ability of cholesterol-conjugated antisense oligonucleotides.

Wada S, Yasuhara H, Wada F, Sawamura M, Waki R, Yamamoto T, Harada-Shiba M, Obika S. Wada S, et al. J Control Release. 2016 Mar 28;226:57-65. doi: 10.1016/j.jconrel.2016.02.007. Epub 2016 Feb 5. J Control Release. 2016. PMID: 26855051

6

Liver-specific inhibition of acyl-coenzyme a:cholesterol acyltransferase 2 with antisense oligonucleotides limits atherosclerosis development in apolipoprotein B100-only low-density lipoprotein receptor-/- mice.

Bell TA 3rd, Brown JM, Graham MJ, Lemonidis KM, Crooke RM, Rudel LL. Bell TA 3rd, et al. Arterioscler Thromb Vasc Biol. 2006 Aug;26(8):1814-20. doi: 10.1161/01.ATV.0000225289.30767.06. Epub 2006 May 4. Arterioscler Thromb Vasc Biol. 2006. PMID: 16675724

7

Pharmacokinetic and Pharmacodynamic Investigations of ION-353382, a Model Antisense Oligonucleotide: Using Alpha-2-Macroglobulin and Murinoglobulin Double-Knockout Mice.

Shemesh CS, Yu RZ, Gaus HJ, Seth PP, Swayze EE, Bennett FC, Geary RS, Henry SP, Wang Y. Shemesh CS, et al. Nucleic Acid Ther. 2016 Aug;26(4):223-35. doi: 10.1089/nat.2016.0607. Epub 2016 Mar 31. Nucleic Acid Ther. 2016. PMID: 27031383

8

Cholesterol-GalNAc Dual Conjugation Strategy for Reducing Renal Distribution of Antisense Oligonucleotides.

Wada F, Yamamoto T, Ueda T, Sawamura M, Wada S, Harada-Shiba M, Obika S. Wada F, et al. Nucleic Acid Ther. 2018 Feb;28(1):50-57. doi: 10.1089/nat.2017.0698. Epub 2018 Jan 23. Nucleic Acid Ther. 2018. PMID: 29360004

9

Comparison of the pharmacological profiles of murine antisense oligonucleotides targeting apolipoprotein B and microsomal triglyceride transfer protein.

Lee RG, Fu W, Graham MJ, Mullick AE, Sipe D, Gattis D, Bell TA, Booten S, Crooke RM. Lee RG, et al. J Lipid Res. 2013 Mar;54(3):602-614. doi: 10.1194/jlr.M029215. Epub 2012 Dec 6. J Lipid Res. 2013. PMID: 23220583 Free PMC article.

10

Mouse genome-wide association studies and systems genetics uncover the genetic architecture associated with hepatic pharmacokinetic and pharmacodynamic properties of a constrained ethyl antisense oligonucleotide targeting Malat1.

Pirie E, Ray S, Pan C, Fu W, Powers AF, Polikoff D, Miller CM, Kudrna KM, Harris EN, Lusis AJ, Crooke RM, Lee RG. Pirie E, et al. PLoS Genet. 2018 Oct 29;14(10):e1007732. doi: 10.1371/journal.pgen.1007732. eCollection 2018 Oct. PLoS Genet. 2018. PMID: 30372444 Free PMC article.

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