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Items: 1 to 20 of 67

1.

Nebulized perflubron and carbon dioxide rapidly dilate constricted airways in an ovine model of allergic asthma.

El Mays TY, Choudhury P, Leigh R, Koumoundouros E, Van der Velden J, Shrestha G, Pieron CA, Dennis JH, Green FH, Snibson KJ.

Respir Res. 2014 Sep 16;15:98. doi: 10.1186/s12931-014-0098-x.

2.

A phase IIa proof-of-concept, placebo-controlled, randomized, double-blind, crossover, single-dose clinical trial of a new class of bronchodilator for acute asthma.

Swystun V, Green FHY, Dennis JH, Rampakakis E, Lalli G, Fadayomi M, Chiu A, Shrestha G, El Shahat SG, Nelson DE, El Mays TY, Pieron CA, Leigh R.

Trials. 2018 Jun 18;19(1):321. doi: 10.1186/s13063-018-2720-6.

3.

A phase I, placebo-controlled, randomized, double-blind, single ascending dose-ranging study to evaluate the safety and tolerability of a novel biophysical bronchodilator (S-1226) administered by nebulization in healthy volunteers.

Green FH, Leigh R, Fadayomi M, Lalli G, Chiu A, Shrestha G, ElShahat SG, Nelson DE, El Mays TY, Pieron CA, Dennis JH.

Trials. 2016 Jul 28;17:361. doi: 10.1186/s13063-016-1489-8.

4.

Chronic airway disease: deteriorating pulmonary function in sheep associated with repeated challenges of house dust mite.

Koumoundouros E, Bischof RJ, Meeusen EN, Mareels IM, Snibson KJ.

Exp Lung Res. 2006 Aug;32(7):321-30.

PMID:
17060175
5.

Assessment of peripheral airway function following chronic allergen challenge in a sheep model of asthma.

Van der Velden J, Barker D, Barcham G, Koumoundouros E, Snibson K.

PLoS One. 2011;6(12):e28740. doi: 10.1371/journal.pone.0028740. Epub 2011 Dec 12.

6.

Increased mast cell density and airway responses to allergic and non-allergic stimuli in a sheep model of chronic asthma.

Van der Velden J, Barker D, Barcham G, Koumoundouros E, Snibson K.

PLoS One. 2012;7(5):e37161. doi: 10.1371/journal.pone.0037161. Epub 2012 May 14.

7.

Proteinase-activated receptor-2 activation participates in allergic sensitization to house dust mite allergens in a murine model.

Davidson CE, Asaduzzaman M, Arizmendi NG, Polley D, Wu Y, Gordon JR, Hollenberg MD, Cameron L, Vliagoftis H.

Clin Exp Allergy. 2013 Nov;43(11):1274-85. doi: 10.1111/cea.12185.

PMID:
24152160
8.

Induction of allergic inflammation in the lungs of sensitized sheep after local challenge with house dust mite.

Bischof RJ, Snibson K, Shaw R, Meeusen EN.

Clin Exp Allergy. 2003 Mar;33(3):367-75.

PMID:
12614452
9.

Comparison of airway responses in sheep of different age in precision-cut lung slices (PCLS).

Lambermont VA, Schlepütz M, Dassow C, König P, Zimmermann LJ, Uhlig S, Kramer BW, Martin C.

PLoS One. 2014 Sep 17;9(9):e97610. doi: 10.1371/journal.pone.0097610. eCollection 2014.

10.

Increased vascular density is a persistent feature of airway remodeling in a sheep model of chronic asthma.

Van der Velden J, Barker D, Barcham G, Koumoundouros E, Snibson K.

Exp Lung Res. 2012 Aug;38(6):307-15. doi: 10.3109/01902148.2012.697975.

PMID:
22734813
11.
12.

Effects of furosemide on allergic asthmatic responses in mice.

Wang S, Xiang YY, Ellis R, Wattie J, Feng M, Inman MD, Lu WY.

Clin Exp Allergy. 2011 Oct;41(10):1456-67. doi: 10.1111/j.1365-2222.2011.03811.x. Epub 2011 Jul 5.

PMID:
21729180
13.

Inhalation of nebulized perfluorochemical enhances recombinant adenovirus and adeno-associated virus-mediated gene expression in lung epithelium.

Beckett T, Bonneau L, Howard A, Blanchard J, Borda J, Weiner DJ, Wang L, Gao GP, Kolls JK, Bohm R, Liggitt D, Weiss DJ.

Hum Gene Ther Methods. 2012 Apr;23(2):98-110. doi: 10.1089/hgtb.2012.014. Epub 2012 May 8.

14.

Allergen-induced bronchial inflammation in house dust mite-allergic patients with or without asthma.

Lopuhaä CE, Out TA, Jansen HM, Aalberse RC, van der Zee JS.

Clin Exp Allergy. 2002 Dec;32(12):1720-7.

PMID:
12653162
15.

A guinea-pig model of ultrasonically nebulized distilled water-induced bronchoconstriction.

Fujimura M, Amemiya M, Myou S, Mizuguchi M, Matsuda T.

Eur Respir J. 1997 Oct;10(10):2237-42.

16.

[Nonspecific inhalative provocation in the sheep as an asthma model--correlation of respiratory and cardiovascular effects].

Marek W, Hoffarth HP, Potthast J, Ulmer WT, Baur X.

Pneumologie. 1994 Jun;48(6):433-42. German.

PMID:
8072989
17.
18.

Immune response to allergens in sheep sensitized to house dust mite.

Bischof RJ, Snibson KJ, Van Der Velden J, Meeusen EN.

J Inflamm (Lond). 2008 Oct 20;5:16. doi: 10.1186/1476-9255-5-16.

19.

Airway remodelling and inflammation in sheep lungs after chronic airway challenge with house dust mite.

Snibson KJ, Bischof RJ, Slocombe RF, Meeusen EN.

Clin Exp Allergy. 2005 Feb;35(2):146-52.

PMID:
15725184
20.

[Effect of phosphodiestrase 4 inhibitor (rolipram) on experimental allergic asthma-guinea pig model].

Nejman-Gryz P, Grubek-Jaworska H, Glapińiski J, Chazan R.

Pneumonol Alergol Pol. 2006;74(1):106-12. Polish.

PMID:
17175988

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