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Items: 1 to 20 of 123

1.

Early double-negative thymocyte export in Trypanosoma cruzi infection is restricted by sphingosine receptors and associated with human chagas disease.

Lepletier A, de Almeida L, Santos L, da Silva Sampaio L, Paredes B, González FB, Freire-de-Lima CG, Beloscar J, Bottasso O, Einicker-Lamas M, Pérez AR, Savino W, Morrot A.

PLoS Negl Trop Dis. 2014 Oct 16;8(10):e3203. doi: 10.1371/journal.pntd.0003203. eCollection 2014 Oct.

2.

Modulation of Intrathymic Sphingosine-1-Phosphate Levels Promotes Escape of Immature Thymocytes to the Periphery with a Potential Proinflammatory Role in Chagas Disease.

Flávia Nardy A, Santos L, Freire-de-Lima CG, Morrot A.

Biomed Res Int. 2015;2015:709846. doi: 10.1155/2015/709846. Epub 2015 Aug 4. Review.

3.

Sphingosine-1-phosphate/sphingosine-1-phosphate receptor 1 signaling is required for migration of naive human T cells from the thymus to the periphery.

Resop RS, Douaisi M, Craft J, Jachimowski LC, Blom B, Uittenbogaart CH.

J Allergy Clin Immunol. 2016 Aug;138(2):551-557.e8. doi: 10.1016/j.jaci.2015.12.1339. Epub 2016 Apr 4.

PMID:
27056271
4.

Chagasic thymic atrophy does not affect negative selection but results in the export of activated CD4+CD8+ T cells in severe forms of human disease.

Morrot A, Terra-Granado E, Pérez AR, Silva-Barbosa SD, Milićević NM, Farias-de-Oliveira DA, Berbert LR, De Meis J, Takiya CM, Beloscar J, Wang X, Kont V, Peterson P, Bottasso O, Savino W.

PLoS Negl Trop Dis. 2011 Aug;5(8):e1268. doi: 10.1371/journal.pntd.0001268. Epub 2011 Aug 16.

5.

TNF-α is involved in the abnormal thymocyte migration during experimental Trypanosoma cruzi infection and favors the export of immature cells.

Pérez AR, Berbert LR, Lepletier A, Revelli S, Bottasso O, Silva-Barbosa SD, Savino W.

PLoS One. 2012;7(3):e34360. doi: 10.1371/journal.pone.0034360. Epub 2012 Mar 26.

6.

Elevated intrathymic sphingosine-1-phosphate promotes thymus involution during sepsis.

Kuchler L, Sha LK, Giegerich AK, Knape T, Angioni C, Ferreirós N, Schmidt MV, Weigert A, Brüne B, von Knethen A.

Mol Immunol. 2017 Oct;90:255-263. doi: 10.1016/j.molimm.2017.08.011. Epub 2017 Aug 30.

PMID:
28846923
7.

S1P lyase in thymic perivascular spaces promotes egress of mature thymocytes via up-regulation of S1P receptor 1.

Maeda Y, Yagi H, Takemoto K, Utsumi H, Fukunari A, Sugahara K, Masuko T, Chiba K.

Int Immunol. 2014 May;26(5):245-55. doi: 10.1093/intimm/dxt069. Epub 2013 Dec 16.

PMID:
24343820
8.

Sphingosine-1-Phosphate Induces Dose-Dependent Chemotaxis or Fugetaxis of T-ALL Blasts through S1P1 Activation.

Messias CV, Santana-Van-Vliet E, Lemos JP, Moreira OC, Cotta-de-Almeida V, Savino W, Mendes-da-Cruz DA.

PLoS One. 2016 Jan 29;11(1):e0148137. doi: 10.1371/journal.pone.0148137. eCollection 2016.

9.

Ceramide synthase 2 facilitates S1P-dependent egress of thymocytes into the circulation in mice.

Rieck M, Kremser C, Jobin K, Mettke E, Kurts C, Gräler M, Willecke K, Kolanus W.

Eur J Immunol. 2017 Apr;47(4):677-684. doi: 10.1002/eji.201646623. Epub 2017 Feb 27.

10.

Trans-sialidase from Trypanosoma cruzi enhances the adhesion properties and fibronectin-driven migration of thymocytes.

Nardy AF, Luiz da Silva Filho J, Pérez AR, de Meis J, Farias-de-Oliveira DA, Penha L, de Araújo Oliveira I, Dias WB, Todeschini AR, Freire-de-Lima CG, Bellio M, Caruso-Neves C, Pinheiro AA, Takiya CM, Bottasso O, Savino W, Morrot A.

Microbes Infect. 2013 May;15(5):365-74. doi: 10.1016/j.micinf.2013.02.003. Epub 2013 Feb 24.

11.

Altered expression of galectin-3 induces cortical thymocyte depletion and premature exit of immature thymocytes during Trypanosoma cruzi infection.

Silva-Monteiro E, Reis Lorenzato L, Kenji Nihei O, Junqueira M, Rabinovich GA, Hsu DK, Liu FT, Savino W, Chammas R, Villa-Verde DM.

Am J Pathol. 2007 Feb;170(2):546-56.

12.

Trypanosoma cruzi disrupts thymic homeostasis by altering intrathymic and systemic stress-related endocrine circuitries.

Lepletier A, de Carvalho VF, Rodrigues e Silva PM, Villar S, Pérez AR, Savino W, Morrot A.

PLoS Negl Trop Dis. 2013 Nov 14;7(11):e2470. doi: 10.1371/journal.pntd.0002470. eCollection 2013 Nov.

13.

Altered bone marrow lymphopoiesis and interleukin-6-dependent inhibition of thymocyte differentiation contribute to thymic atrophy during Trypanosoma cruzi infection.

Carbajosa S, Gea S, Chillón-Marinas C, Poveda C, Del Carmen Maza M, Fresno M, Gironès N.

Oncotarget. 2017 Mar 14;8(11):17551-17561. doi: 10.18632/oncotarget.14886.

14.

Caspase-8 and caspase-9 mediate thymocyte apoptosis in Trypanosoma cruzi acutely infected mice.

Farias-de-Oliveira DA, Villa-Verde DM, Nunes Panzenhagen PH, Silva dos Santos D, Berbert LR, Savino W, de Meis J.

J Leukoc Biol. 2013 Feb;93(2):227-34. doi: 10.1189/jlb.1211589. Epub 2012 Nov 16.

PMID:
23159925
15.

Sphingosine 1-phosphate receptor type 1 regulates egress of mature T cells from mouse bone marrow.

Maeda Y, Seki N, Sato N, Sugahara K, Chiba K.

Int Immunol. 2010 Jun;22(6):515-25. doi: 10.1093/intimm/dxq036. Epub 2010 May 23.

PMID:
20497959
16.

The sphingosine-1-phosphate/sphingosine-1-phosphate receptor 2 axis regulates early airway T-cell infiltration in murine mast cell-dependent acute allergic responses.

Oskeritzian CA, Hait NC, Wedman P, Chumanevich A, Kolawole EM, Price MM, Falanga YT, Harikumar KB, Ryan JJ, Milstien S, Sabbadini R, Spiegel S.

J Allergy Clin Immunol. 2015 Apr;135(4):1008-18.e1. doi: 10.1016/j.jaci.2014.10.044. Epub 2014 Dec 13.

17.

Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network.

Rosen H, Goetzl EJ.

Nat Rev Immunol. 2005 Jul;5(7):560-70. Review.

PMID:
15999095
18.

Sphingosine-1-phosphate receptor expression in cardiac fibroblasts is modulated by in vitro culture conditions.

Landeen LK, Aroonsakool N, Haga JH, Hu BS, Giles WR.

Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H2698-711. Epub 2007 Mar 2.

19.

Involvement of sphingosine 1-phosphate (S1P) receptor type 1 and type 4 in migratory response of mouse T cells toward S1P.

Matsuyuki H, Maeda Y, Yano K, Sugahara K, Chiba K, Kohno T, Igarashi Y.

Cell Mol Immunol. 2006 Dec;3(6):429-37.

20.

[Effects of sphingosine 1-phosphate on functions of T cell - review].

Huang WR, Wang LS, DA WM.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2005 Aug;13(4):718-22. Chinese.

PMID:
16129068

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