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Items: 1 to 20 of 114

1.

The ER-associated protein ZDHHC1 is a positive regulator of DNA virus-triggered, MITA/STING-dependent innate immune signaling.

Zhou Q, Lin H, Wang S, Wang S, Ran Y, Liu Y, Ye W, Xiong X, Zhong B, Shu HB, Wang YY.

Cell Host Microbe. 2014 Oct 8;16(4):450-61. doi: 10.1016/j.chom.2014.09.006.

2.

SNX8 modulates innate immune response to DNA virus by mediating trafficking and activation of MITA.

Wei J, Lian H, Guo W, Chen YD, Zhang XN, Zang R, Zhong L, Yang Q, Hu MM, Luo WW, Shu HB, Li S.

PLoS Pathog. 2018 Oct 15;14(10):e1007336. doi: 10.1371/journal.ppat.1007336. eCollection 2018 Oct.

3.

NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING.

Zhang L, Mo J, Swanson KV, Wen H, Petrucelli A, Gregory SM, Zhang Z, Schneider M, Jiang Y, Fitzgerald KA, Ouyang S, Liu ZJ, Damania B, Shu HB, Duncan JA, Ting JP.

Immunity. 2014 Mar 20;40(3):329-41. doi: 10.1016/j.immuni.2014.01.010. Epub 2014 Feb 20. Review.

4.

Endoplasmic Reticulum Transmembrane Proteins ZDHHC1 and STING Both Act as Direct Adaptors for IRF3 Activation in Teleost.

Xu X, Li M, Wu Z, Wang H, Wang L, Huang K, Liu X, Hou Q, Lin G, Hu C.

J Immunol. 2017 Nov 15;199(10):3623-3633. doi: 10.4049/jimmunol.1700750. Epub 2017 Oct 18.

5.

USP49 negatively regulates cellular antiviral responses via deconjugating K63-linked ubiquitination of MITA.

Ye L, Zhang Q, Liuyu T, Xu Z, Zhang MX, Luo MH, Zeng WB, Zhu Q, Lin D, Zhong B.

PLoS Pathog. 2019 Apr 3;15(4):e1007680. doi: 10.1371/journal.ppat.1007680. eCollection 2019 Apr.

6.

Evasion of the STING DNA-Sensing Pathway by VP11/12 of Herpes Simplex Virus 1.

Deschamps T, Kalamvoki M.

J Virol. 2017 Jul 27;91(16). pii: e00535-17. doi: 10.1128/JVI.00535-17. Print 2017 Aug 15.

7.

ZDHHC11 modulates innate immune response to DNA virus by mediating MITA-IRF3 association.

Liu Y, Zhou Q, Zhong L, Lin H, Hu MM, Zhou Y, Shu HB, Li S.

Cell Mol Immunol. 2018 Oct;15(10):907-916. doi: 10.1038/cmi.2017.146. Epub 2018 Feb 12.

PMID:
29429998
8.

USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA.

Zhang M, Zhang MX, Zhang Q, Zhu GF, Yuan L, Zhang DE, Zhu Q, Yao J, Shu HB, Zhong B.

Cell Res. 2016 Dec;26(12):1302-1319. doi: 10.1038/cr.2016.125. Epub 2016 Nov 1.

9.

TRIM32 protein modulates type I interferon induction and cellular antiviral response by targeting MITA/STING protein for K63-linked ubiquitination.

Zhang J, Hu MM, Wang YY, Shu HB.

J Biol Chem. 2012 Aug 17;287(34):28646-55. doi: 10.1074/jbc.M112.362608. Epub 2012 Jun 28.

10.

The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA.

Zhong B, Zhang L, Lei C, Li Y, Mao AP, Yang Y, Wang YY, Zhang XL, Shu HB.

Immunity. 2009 Mar 20;30(3):397-407. doi: 10.1016/j.immuni.2009.01.008. Epub 2009 Mar 12.

11.

STING Requires the Adaptor TRIF to Trigger Innate Immune Responses to Microbial Infection.

Wang X, Majumdar T, Kessler P, Ozhegov E, Zhang Y, Chattopadhyay S, Barik S, Sen GC.

Cell Host Microbe. 2016 Sep 14;20(3):329-341. doi: 10.1016/j.chom.2016.08.002. Erratum in: Cell Host Microbe. 2017 Jun 14;21(6):788.

12.

MITA/STING and Its Alternative Splicing Isoform MRP Restrict Hepatitis B Virus Replication.

Liu S, Zhao K, Su X, Lu L, Zhao H, Zhang X, Wang Y, Wu C, Chen J, Zhou Y, Hu X, Wang Y, Lu M, Chen X, Pei R.

PLoS One. 2017 Jan 5;12(1):e0169701. doi: 10.1371/journal.pone.0169701. eCollection 2017.

13.

The E3 ubiquitin ligase AMFR and INSIG1 bridge the activation of TBK1 kinase by modifying the adaptor STING.

Wang Q, Liu X, Cui Y, Tang Y, Chen W, Li S, Yu H, Pan Y, Wang C.

Immunity. 2014 Dec 18;41(6):919-33. doi: 10.1016/j.immuni.2014.11.011. Epub 2014 Nov 28.

14.

Herpes Simplex Virus 1 Serine Protease VP24 Blocks the DNA-Sensing Signal Pathway by Abrogating Activation of Interferon Regulatory Factor 3.

Zhang D, Su C, Zheng C.

J Virol. 2016 May 27;90(12):5824-5829. doi: 10.1128/JVI.00186-16. Print 2016 Jun 15.

15.

Herpes Simplex Virus 1 Tegument Protein VP22 Abrogates cGAS/STING-Mediated Antiviral Innate Immunity.

Huang J, You H, Su C, Li Y, Chen S, Zheng C.

J Virol. 2018 Jul 17;92(15). pii: e00841-18. doi: 10.1128/JVI.00841-18. Print 2018 Aug 1.

16.

Herpes Simplex Virus 1 γ134.5 Protein Inhibits STING Activation That Restricts Viral Replication.

Pan S, Liu X, Ma Y, Cao Y, He B.

J Virol. 2018 Sep 26;92(20). pii: e01015-18. doi: 10.1128/JVI.01015-18. Print 2018 Oct 15.

17.

Herpes Simplex Virus 1 Abrogates the cGAS/STING-Mediated Cytosolic DNA-Sensing Pathway via Its Virion Host Shutoff Protein, UL41.

Su C, Zheng C.

J Virol. 2017 Feb 28;91(6). pii: e02414-16. doi: 10.1128/JVI.02414-16. Print 2017 Mar 15.

18.

TMED2 Potentiates Cellular IFN Responses to DNA Viruses by Reinforcing MITA Dimerization and Facilitating Its Trafficking.

Sun MS, Zhang J, Jiang LQ, Pan YX, Tan JY, Yu F, Guo L, Yin L, Shen C, Shu HB, Liu Y.

Cell Rep. 2018 Dec 11;25(11):3086-3098.e3. doi: 10.1016/j.celrep.2018.11.048.

19.

MITA/STING: a central and multifaceted mediator in innate immune response.

Ran Y, Shu HB, Wang YY.

Cytokine Growth Factor Rev. 2014 Dec;25(6):631-9. doi: 10.1016/j.cytogfr.2014.05.003. Epub 2014 May 20. Review.

PMID:
24929887
20.

A STING-dependent innate-sensing pathway mediates resistance to corneal HSV-1 infection via upregulation of the antiviral effector tetherin.

Royer DJ, Carr DJ.

Mucosal Immunol. 2016 Jul;9(4):1065-75. doi: 10.1038/mi.2015.124. Epub 2015 Dec 2.

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