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Items: 1 to 20 of 204

1.

Feedback regulation via AMPK and HIF-1 mediates ROS-dependent longevity in Caenorhabditis elegans.

Hwang AB, Ryu EA, Artan M, Chang HW, Kabir MH, Nam HJ, Lee D, Yang JS, Kim S, Mair WB, Lee C, Lee SS, Lee SJ.

Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4458-67. doi: 10.1073/pnas.1411199111. Epub 2014 Oct 6.

2.

Regulation of life span by mitochondrial respiration: the HIF-1 and ROS connection.

Hwang AB, Lee SJ.

Aging (Albany NY). 2011 Mar;3(3):304-10. Review.

3.

Inhibition of respiration extends C. elegans life span via reactive oxygen species that increase HIF-1 activity.

Lee SJ, Hwang AB, Kenyon C.

Curr Biol. 2010 Dec 7;20(23):2131-6. doi: 10.1016/j.cub.2010.10.057. Epub 2010 Nov 18.

4.

Elucidating the Mechanism of Weissella-dependent Lifespan Extension in Caenorhabditis elegans.

Lee J, Kwon G, Lim YH.

Sci Rep. 2015 Nov 25;5:17128. doi: 10.1038/srep17128.

5.

Lonidamine extends lifespan of adult Caenorhabditis elegans by increasing the formation of mitochondrial reactive oxygen species.

Schmeisser S, Zarse K, Ristow M.

Horm Metab Res. 2011 Sep;43(10):687-92. doi: 10.1055/s-0031-1286308. Epub 2011 Sep 19.

PMID:
21932172
6.

Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB.

Mair W, Morantte I, Rodrigues AP, Manning G, Montminy M, Shaw RJ, Dillin A.

Nature. 2011 Feb 17;470(7334):404-8. doi: 10.1038/nature09706.

7.

Synergism between soluble guanylate cyclase signaling and neuropeptides extends lifespan in the nematode Caenorhabditis elegans.

Abergel R, Livshits L, Shaked M, Chatterjee AK, Gross E.

Aging Cell. 2017 Apr;16(2):401-413. doi: 10.1111/acel.12569. Epub 2017 Jan 4.

8.

Roles for ROS and hydrogen sulfide in the longevity response to germline loss in Caenorhabditis elegans.

Wei Y, Kenyon C.

Proc Natl Acad Sci U S A. 2016 May 17;113(20):E2832-41. doi: 10.1073/pnas.1524727113. Epub 2016 May 2.

9.

Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans.

Edwards C, Canfield J, Copes N, Brito A, Rehan M, Lipps D, Brunquell J, Westerheide SD, Bradshaw PC.

BMC Genet. 2015 Feb 3;16:8. doi: 10.1186/s12863-015-0167-2.

10.

Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans.

Morcos M, Du X, Pfisterer F, Hutter H, Sayed AA, Thornalley P, Ahmed N, Baynes J, Thorpe S, Kukudov G, Schlotterer A, Bozorgmehr F, El Baki RA, Stern D, Moehrlen F, Ibrahim Y, Oikonomou D, Hamann A, Becker C, Zeier M, Schwenger V, Miftari N, Humpert P, Hammes HP, Buechler M, Bierhaus A, Brownlee M, Nawroth PP.

Aging Cell. 2008 Mar;7(2):260-9. doi: 10.1111/j.1474-9726.2008.00371.x. Epub 2008 Jan 21.

11.

Inhibition of elongin C promotes longevity and protein homeostasis via HIF-1 in C. elegans.

Hwang W, Artan M, Seo M, Lee D, Nam HG, Lee SJ.

Aging Cell. 2015 Dec;14(6):995-1002. doi: 10.1111/acel.12390. Epub 2015 Sep 11.

12.

A Mutation in Caenorhabditis elegans NDUF-7 Activates the Mitochondrial Stress Response and Prolongs Lifespan via ROS and CED-4.

Rauthan M, Ranji P, Abukar R, Pilon M.

G3 (Bethesda). 2015 Jun 1;5(8):1639-48. doi: 10.1534/g3.115.018598.

13.

HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans.

Chen D, Thomas EL, Kapahi P.

PLoS Genet. 2009 May;5(5):e1000486. doi: 10.1371/journal.pgen.1000486. Epub 2009 May 22.

14.

A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans.

Yang W, Hekimi S.

PLoS Biol. 2010 Dec 7;8(12):e1000556. doi: 10.1371/journal.pbio.1000556.

15.

Chicoric acid is an antioxidant molecule that stimulates AMP kinase pathway in L6 myotubes and extends lifespan in Caenorhabditis elegans.

Schlernitzauer A, Oiry C, Hamad R, Galas S, Cortade F, Chabi B, Casas F, Pessemesse L, Fouret G, Feillet-Coudray C, Cros G, Cabello G, Magous R, Wrutniak-Cabello C.

PLoS One. 2013 Nov 11;8(11):e78788. doi: 10.1371/journal.pone.0078788. eCollection 2013.

16.
17.

Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway.

Fang EF, Waltz TB, Kassahun H, Lu Q, Kerr JS, Morevati M, Fivenson EM, Wollman BN, Marosi K, Wilson MA, Iser WB, Eckley DM, Zhang Y, Lehrmann E, Goldberg IG, Scheibye-Knudsen M, Mattson MP, Nilsen H, Bohr VA, Becker KG.

Sci Rep. 2017 Apr 11;7:46208. doi: 10.1038/srep46208.

18.

Uncoupling of oxidative stress resistance and lifespan in long-lived isp-1 mitochondrial mutants in Caenorhabditis elegans.

Dues DJ, Schaar CE, Johnson BK, Bowman MJ, Winn ME, Senchuk MM, Van Raamsdonk JM.

Free Radic Biol Med. 2017 Jul;108:362-373. doi: 10.1016/j.freeradbiomed.2017.04.004. Epub 2017 Apr 7.

19.

The Caenorhabditis elegans germ line regulates distinct signaling pathways to control lifespan and innate immunity.

Alper S, McElwee MK, Apfeld J, Lackford B, Freedman JH, Schwartz DA.

J Biol Chem. 2010 Jan 15;285(3):1822-8. doi: 10.1074/jbc.M109.057323. Epub 2009 Nov 18.

20.

Loss of hif-1 promotes resistance to the exogenous mitochondrial stressor ethidium bromide in Caenorhabditis elegans.

Kamal M, D'Amora DR, Kubiseski TJ.

BMC Cell Biol. 2016 Sep 13;17 Suppl 1:34. doi: 10.1186/s12860-016-0112-x.

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