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Items: 1 to 20 of 198

1.

CARD9 mediates Dectin-1-induced ERK activation by linking Ras-GRF1 to H-Ras for antifungal immunity.

Jia XM, Tang B, Zhu LL, Liu YH, Zhao XQ, Gorjestani S, Hsu YM, Yang L, Guan JH, Xu GT, Lin X.

J Exp Med. 2014 Oct 20;211(11):2307-21. doi: 10.1084/jem.20132349. Epub 2014 Sep 29.

2.

CARD9 mediates dectin-2-induced IkappaBalpha kinase ubiquitination leading to activation of NF-kappaB in response to stimulation by the hyphal form of Candida albicans.

Bi L, Gojestani S, Wu W, Hsu YM, Zhu J, Ariizumi K, Lin X.

J Biol Chem. 2010 Aug 20;285(34):25969-77. doi: 10.1074/jbc.M110.131300. Epub 2010 Jun 9.

3.

CARD9 Syk-dependent and Raf-1 Syk-independent signaling pathways in target recognition of Candida albicans by Dectin-1.

Yang H, He H, Dong Y.

Eur J Clin Microbiol Infect Dis. 2011 Mar;30(3):303-5. doi: 10.1007/s10096-010-1103-z. Epub 2010 Nov 25. Review.

PMID:
21108038
4.

Phospholipase Cgamma2 is critical for Dectin-1-mediated Ca2+ flux and cytokine production in dendritic cells.

Xu S, Huo J, Lee KG, Kurosaki T, Lam KP.

J Biol Chem. 2009 Mar 13;284(11):7038-46. doi: 10.1074/jbc.M806650200. Epub 2009 Jan 9.

5.

C-type lectin receptor dectin-3 mediates trehalose 6,6'-dimycolate (TDM)-induced Mincle expression through CARD9/Bcl10/MALT1-dependent nuclear factor (NF)-κB activation.

Zhao XQ, Zhu LL, Chang Q, Jiang C, You Y, Luo T, Jia XM, Lin X.

J Biol Chem. 2014 Oct 24;289(43):30052-62. doi: 10.1074/jbc.M114.588574. Epub 2014 Sep 8.

6.

Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity.

Gross O, Gewies A, Finger K, Schäfer M, Sparwasser T, Peschel C, Förster I, Ruland J.

Nature. 2006 Aug 10;442(7103):651-6. Epub 2006 Jul 12.

PMID:
16862125
7.

Syk kinase-coupled C-type lectin receptors engage protein kinase C-σ to elicit Card9 adaptor-mediated innate immunity.

Strasser D, Neumann K, Bergmann H, Marakalala MJ, Guler R, Rojowska A, Hopfner KP, Brombacher F, Urlaub H, Baier G, Brown GD, Leitges M, Ruland J.

Immunity. 2012 Jan 27;36(1):32-42. doi: 10.1016/j.immuni.2011.11.015.

8.

Vav Proteins Are Key Regulators of Card9 Signaling for Innate Antifungal Immunity.

Roth S, Bergmann H, Jaeger M, Yeroslaviz A, Neumann K, Koenig PA, Prazeres da Costa C, Vanes L, Kumar V, Johnson M, Menacho-Márquez M, Habermann B, Tybulewicz VL, Netea M, Bustelo XR, Ruland J.

Cell Rep. 2016 Dec 6;17(10):2572-2583. doi: 10.1016/j.celrep.2016.11.018.

9.

Dectin-1 and Dectin-2 in innate immunity against fungi.

Saijo S, Iwakura Y.

Int Immunol. 2011 Aug;23(8):467-72. doi: 10.1093/intimm/dxr046. Epub 2011 Jun 15. Review.

PMID:
21677049
10.

CARD9 signaling in the innate immune response.

Ruland J.

Ann N Y Acad Sci. 2008 Nov;1143:35-44. doi: 10.1196/annals.1443.024. Review.

PMID:
19076343
11.

Impaired RASGRF1/ERK-mediated GM-CSF response characterizes CARD9 deficiency in French-Canadians.

Gavino C, Hamel N, Zeng JB, Legault C, Guiot MC, Chankowsky J, Lejtenyi D, Lemire M, Alarie I, Dufresne S, Boursiquot JN, McIntosh F, Langelier M, Behr MA, Sheppard DC, Foulkes WD, Vinh DC.

J Allergy Clin Immunol. 2016 Apr;137(4):1178-1188.e7. doi: 10.1016/j.jaci.2015.09.016. Epub 2015 Oct 29.

PMID:
26521038
12.

The role of Dectin-1 in the host defence against fungal infections.

Drummond RA, Brown GD.

Curr Opin Microbiol. 2011 Aug;14(4):392-9. doi: 10.1016/j.mib.2011.07.001. Epub 2011 Jul 29. Review.

PMID:
21803640
13.

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection.

Robinson MJ, Osorio F, Rosas M, Freitas RP, Schweighoffer E, Gross O, Verbeek JS, Ruland J, Tybulewicz V, Brown GD, Moita LF, Taylor PR, Reis e Sousa C.

J Exp Med. 2009 Aug 31;206(9):2037-51. doi: 10.1084/jem.20082818. Epub 2009 Aug 24.

14.

The autophagy regulator Rubicon is a feedback inhibitor of CARD9-mediated host innate immunity.

Yang CS, Rodgers M, Min CK, Lee JS, Kingeter L, Lee JY, Jong A, Kramnik I, Lin X, Jung JU.

Cell Host Microbe. 2012 Mar 15;11(3):277-89. doi: 10.1016/j.chom.2012.01.019.

15.

Mechanistic Insights into the Role of C-Type Lectin Receptor/CARD9 Signaling in Human Antifungal Immunity.

Drummond RA, Lionakis MS.

Front Cell Infect Microbiol. 2016 Apr 5;6:39. doi: 10.3389/fcimb.2016.00039. eCollection 2016. Review.

16.

Dectin-1-mediated signaling leads to characteristic gene expressions and cytokine secretion via spleen tyrosine kinase (Syk) in rat mast cells.

Kimura Y, Chihara K, Honjoh C, Takeuchi K, Yamauchi S, Yoshiki H, Fujieda S, Sada K.

J Biol Chem. 2014 Nov 7;289(45):31565-75. doi: 10.1074/jbc.M114.581322. Epub 2014 Sep 22.

17.

PKC-δ activation in neutrophils promotes fungal clearance.

Li X, Cullere X, Nishi H, Saggu G, Durand E, Mansour MK, Tam JM, Song XY, Lin X, Vyas JM, Mayadas T.

J Leukoc Biol. 2016 Sep;100(3):581-8. doi: 10.1189/jlb.4A0915-405R. Epub 2016 Mar 10.

PMID:
26965632
18.

Fungal-derived cues promote ocular autoimmunity through a Dectin-2/Card9-mediated mechanism.

Brown BR, Lee EJ, Snow PE, Vance EE, Iwakura Y, Ohno N, Miura N, Lin X, Brown GD, Wells CA, Smith JR, Caspi RR, Rosenzweig HL.

Clin Exp Immunol. 2017 Dec;190(3):293-303. doi: 10.1111/cei.13021. Epub 2017 Aug 30.

PMID:
28763100
19.

Autoimmune regulator (AIRE) contributes to Dectin-1-induced TNF-α production and complexes with caspase recruitment domain-containing protein 9 (CARD9), spleen tyrosine kinase (Syk), and Dectin-1.

Pedroza LA, Kumar V, Sanborn KB, Mace EM, Niinikoski H, Nadeau K, Vasconcelos Dde M, Perez E, Jyonouchi S, Jyonouchi H, Banerjee PP, Ruuskanen O, Condino-Neto A, Orange JS.

J Allergy Clin Immunol. 2012 Feb;129(2):464-72, 472.e1-3. doi: 10.1016/j.jaci.2011.08.027. Epub 2011 Sep 29.

PMID:
21962774
20.

Dectin-2 is a pattern recognition receptor for fungi that couples with the Fc receptor gamma chain to induce innate immune responses.

Sato K, Yang XL, Yudate T, Chung JS, Wu J, Luby-Phelps K, Kimberly RP, Underhill D, Cruz PD Jr, Ariizumi K.

J Biol Chem. 2006 Dec 15;281(50):38854-66. Epub 2006 Oct 18.

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