Similar articles for PMID: 25263562

Year	Number of Results
2008	4
2009	2
2010	2
2011	3
2012	10
2013	20
2014	20
2015	25
2016	18
2017	6
2018	8
2019	9
2020	5
2021	12
2022	27
2023	13
2024	1

1

The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1.

Chantranupong L, Wolfson RL, Orozco JM, Saxton RA, Scaria SM, Bar-Peled L, Spooner E, Isasa M, Gygi SP, Sabatini DM. Chantranupong L, et al. Cell Rep. 2014 Oct 9;9(1):1-8. doi: 10.1016/j.celrep.2014.09.014. Epub 2014 Sep 25. Cell Rep. 2014. PMID: 25263562 Free PMC article.

2

Sestrins inhibit mTORC1 kinase activation through the GATOR complex.

Parmigiani A, Nourbakhsh A, Ding B, Wang W, Kim YC, Akopiants K, Guan KL, Karin M, Budanov AV. Parmigiani A, et al. Cell Rep. 2014 Nov 20;9(4):1281-91. doi: 10.1016/j.celrep.2014.10.019. Cell Rep. 2014. PMID: 25457612 Free PMC article.

3

A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1.

Bar-Peled L, Chantranupong L, Cherniack AD, Chen WW, Ottina KA, Grabiner BC, Spear ED, Carter SL, Meyerson M, Sabatini DM. Bar-Peled L, et al. Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. Science. 2013. PMID: 23723238 Free PMC article.

4

Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling.

Peng M, Yin N, Li MO. Peng M, et al. Cell. 2014 Sep 25;159(1):122-133. doi: 10.1016/j.cell.2014.08.038. Cell. 2014. PMID: 25259925 Free PMC article.

5

KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.

Wolfson RL, Chantranupong L, Wyant GA, Gu X, Orozco JM, Shen K, Condon KJ, Petri S, Kedir J, Scaria SM, Abu-Remaileh M, Frankel WN, Sabatini DM. Wolfson RL, et al. Nature. 2017 Mar 16;543(7645):438-442. doi: 10.1038/nature21423. Epub 2017 Feb 15. Nature. 2017. PMID: 28199306 Free PMC article.

6

SZT2 dictates GATOR control of mTORC1 signalling.

Peng M, Yin N, Li MO. Peng M, et al. Nature. 2017 Mar 16;543(7645):433-437. doi: 10.1038/nature21378. Epub 2017 Feb 15. Nature. 2017. PMID: 28199315 Free PMC article.

7

Amino Acid-Induced Activation of mTORC1 in Rat Liver Is Attenuated by Short-Term Consumption of a High-Fat Diet.

Kimball SR, Ravi S, Gordon BS, Dennis MD, Jefferson LS. Kimball SR, et al. J Nutr. 2015 Nov;145(11):2496-502. doi: 10.3945/jn.115.215491. Epub 2015 Sep 23. J Nutr. 2015. PMID: 26400964 Free PMC article.

8

Sestrin2 inhibits mTORC1 through modulation of GATOR complexes.

Kim JS, Ro SH, Kim M, Park HW, Semple IA, Park H, Cho US, Wang W, Guan KL, Karin M, Lee JH. Kim JS, et al. Sci Rep. 2015 Mar 30;5:9502. doi: 10.1038/srep09502. Sci Rep. 2015. PMID: 25819761 Free PMC article.

9

The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1.

Tsun ZY, Bar-Peled L, Chantranupong L, Zoncu R, Wang T, Kim C, Spooner E, Sabatini DM. Tsun ZY, et al. Mol Cell. 2013 Nov 21;52(4):495-505. doi: 10.1016/j.molcel.2013.09.016. Epub 2013 Oct 3. Mol Cell. 2013. PMID: 24095279 Free PMC article.

10

Sestrin2 is a leucine sensor for the mTORC1 pathway.

Wolfson RL, Chantranupong L, Saxton RA, Shen K, Scaria SM, Cantor JR, Sabatini DM. Wolfson RL, et al. Science. 2016 Jan 1;351(6268):43-8. doi: 10.1126/science.aab2674. Epub 2015 Oct 8. Science. 2016. PMID: 26449471 Free PMC article.

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