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Items: 1 to 20 of 390

1.

miR-184 regulates ezrin, LAMP-1 expression, affects phagocytosis in human retinal pigment epithelium and is downregulated in age-related macular degeneration.

Murad N, Kokkinaki M, Gunawardena N, Gunawan MS, Hathout Y, Janczura KJ, Theos AC, Golestaneh N.

FEBS J. 2014 Dec;281(23):5251-64. doi: 10.1111/febs.13066. Epub 2014 Oct 13.

2.

Effect of miR-23 on oxidant-induced injury in human retinal pigment epithelial cells.

Lin H, Qian J, Castillo AC, Long B, Keyes KT, Chen G, Ye Y.

Invest Ophthalmol Vis Sci. 2011 Aug 9;52(9):6308-14. doi: 10.1167/iovs.10-6632.

PMID:
21693609
3.

MicroRNA-184 promotes differentiation of the retinal pigment epithelium by targeting the AKT2/mTOR signaling pathway.

Jiang C, Qin B, Liu G, Sun X, Shi H, Ding S, Liu Y, Zhu M, Chen X, Zhao C.

Oncotarget. 2016 Aug 9;7(32):52340-52353. doi: 10.18632/oncotarget.10566.

4.

Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration.

Golestaneh N, Chu Y, Xiao YY, Stoleru GL, Theos AC.

Cell Death Dis. 2017 Jan 5;8(1):e2537. doi: 10.1038/cddis.2016.453.

5.

Age-related changes of cystatin C expression and polarized secretion by retinal pigment epithelium: potential age-related macular degeneration links.

Kay P, Yang YC, Hiscott P, Gray D, Maminishkis A, Paraoan L.

Invest Ophthalmol Vis Sci. 2014 Feb 14;55(2):926-34. doi: 10.1167/iovs.13-13239.

PMID:
24458156
6.

Dysfunction of the retinal pigment epithelium with age: increased iron decreases phagocytosis and lysosomal activity.

Chen H, Lukas TJ, Du N, Suyeoka G, Neufeld AH.

Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1895-902. doi: 10.1167/iovs.08-2850. Epub 2009 Jan 17.

PMID:
19151392
7.
8.

A method to enhance cell survival on Bruch's membrane in eyes affected by age and age-related macular degeneration.

Sugino IK, Rapista A, Sun Q, Wang J, Nunes CF, Cheewatrakoolpong N, Zarbin MA.

Invest Ophthalmol Vis Sci. 2011 Dec 20;52(13):9598-609. doi: 10.1167/iovs.11-8400.

PMID:
22039244
9.

Altered bioenergetics and enhanced resistance to oxidative stress in human retinal pigment epithelial cells from donors with age-related macular degeneration.

Ferrington DA, Ebeling MC, Kapphahn RJ, Terluk MR, Fisher CR, Polanco JR, Roehrich H, Leary MM, Geng Z, Dutton JR, Montezuma SR.

Redox Biol. 2017 Oct;13:255-265. doi: 10.1016/j.redox.2017.05.015. Epub 2017 Jun 1.

10.

Comparison of Mouse and Human Retinal Pigment Epithelium Gene Expression Profiles: Potential Implications for Age-Related Macular Degeneration.

Bennis A, Gorgels TG, Ten Brink JB, van der Spek PJ, Bossers K, Heine VM, Bergen AA.

PLoS One. 2015 Oct 30;10(10):e0141597. doi: 10.1371/journal.pone.0141597. eCollection 2015.

11.

Complement factor C3a alters proteasome function in human RPE cells and in an animal model of age-related RPE degeneration.

Ramos de Carvalho JE, Klaassen I, Vogels IM, Schipper-Krom S, van Noorden CJ, Reits E, Gorgels TG, Bergen AA, Schlingemann RO.

Invest Ophthalmol Vis Sci. 2013 Oct 3;54(10):6489-501. doi: 10.1167/iovs.13-12374.

PMID:
23982842
12.

Bruch's membrane aging decreases phagocytosis of outer segments by retinal pigment epithelium.

Sun K, Cai H, Tezel TH, Paik D, Gaillard ER, Del Priore LV.

Mol Vis. 2007 Dec 21;13:2310-9.

PMID:
18199972
14.

Reduced zinc and copper in the retinal pigment epithelium and choroid in age-related macular degeneration.

Erie JC, Good JA, Butz JA, Pulido JS.

Am J Ophthalmol. 2009 Feb;147(2):276-282.e1. doi: 10.1016/j.ajo.2008.08.014. Epub 2008 Oct 9.

PMID:
18848316
15.

Lipofuscin redistribution and loss accompanied by cytoskeletal stress in retinal pigment epithelium of eyes with age-related macular degeneration.

Ach T, Tolstik E, Messinger JD, Zarubina AV, Heintzmann R, Curcio CA.

Invest Ophthalmol Vis Sci. 2015 May;56(5):3242-52. doi: 10.1167/iovs.14-16274.

16.

Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium.

Yao J, Jia L, Khan N, Lin C, Mitter SK, Boulton ME, Dunaief JL, Klionsky DJ, Guan JL, Thompson DA, Zacks DN.

Autophagy. 2015;11(6):939-53. doi: 10.1080/15548627.2015.1041699.

17.

Inhibitory effect of microRNA-34a on retinal pigment epithelial cell proliferation and migration.

Hou Q, Tang J, Wang Z, Wang C, Chen X, Hou L, Dong XD, Tu L.

Invest Ophthalmol Vis Sci. 2013 Oct 3;54(10):6481-8. doi: 10.1167/iovs.13-11873.

PMID:
23970470
18.

Elevated amyloid β production in senescent retinal pigment epithelium, a possible mechanism of subretinal deposition of amyloid β in age-related macular degeneration.

Wang J, Ohno-Matsui K, Morita I.

Biochem Biophys Res Commun. 2012 Jun 22;423(1):73-8. doi: 10.1016/j.bbrc.2012.05.085. Epub 2012 May 23.

PMID:
22634014
19.

RPE phagocytic function declines in age-related macular degeneration and is rescued by human umbilical tissue derived cells.

Inana G, Murat C, An W, Yao X, Harris IR, Cao J.

J Transl Med. 2018 Mar 13;16(1):63. doi: 10.1186/s12967-018-1434-6.

20.

Interleukin-18 induces retinal pigment epithelium degeneration in mice.

Ijima R, Kaneko H, Ye F, Nagasaka Y, Takayama K, Kataoka K, Kachi S, Iwase T, Terasaki H.

Invest Ophthalmol Vis Sci. 2014 Sep 18;55(10):6673-8. doi: 10.1167/iovs.14-15367.

PMID:
25237159

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