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Items: 1 to 20 of 120

1.

Sonic hedgehog signaling in Basal cell nevus syndrome.

Athar M, Li C, Kim AL, Spiegelman VS, Bickers DR.

Cancer Res. 2014 Sep 15;74(18):4967-75. doi: 10.1158/0008-5472.CAN-14-1666. Epub 2014 Aug 29. Review.

2.

Shh and p50/Bcl3 signaling crosstalk drives pathogenesis of BCCs in Gorlin syndrome.

Chaudhary SC, Tang X, Arumugam A, Li C, Srivastava RK, Weng Z, Xu J, Zhang X, Kim AL, McKay K, Elmets CA, Kopelovich L, Bickers DR, Athar M.

Oncotarget. 2015 Nov 3;6(34):36789-814. doi: 10.18632/oncotarget.5103.

3.

The immunoprofile of odontogenic keratocyst (keratocystic odontogenic tumor) that includes expression of PTCH, SMO, GLI-1 and bcl-2 is similar to ameloblastoma but different from odontogenic cysts.

Vered M, Peleg O, Taicher S, Buchner A.

J Oral Pathol Med. 2009 Aug;38(7):597-604. doi: 10.1111/j.1600-0714.2009.00778.x. Epub 2009 Apr 16.

PMID:
19473442
4.

Analysis of mutation in exon 17 of PTCH in patients with nevoid basal cell carcinoma syndrome.

Li J, Wang J, Liu Y, Wang W.

Mol Biol Rep. 2010 Jan;37(1):359-62. doi: 10.1007/s11033-009-9782-1.

PMID:
19728145
5.

Basal cell nevus syndrome: clinical and molecular review and case report.

Pino LC, Balassiano LK, Sessim M, de Almeida AP, Empinotti VD, Semenovitch I, Treu C, Lupi O.

Int J Dermatol. 2016 Apr;55(4):367-75. doi: 10.1111/ijd.12993. Epub 2015 Sep 10. Review.

PMID:
26356331
6.

Basal Cell Carcinoma in Gorlin's Patients: a Matter of Fibroblasts-Led Protumoral Microenvironment?

Gache Y, Brellier F, Rouanet S, Al-Qaraghuli S, Goncalves-Maia M, Burty-Valin E, Barnay S, Scarzello S, Ruat M, Sevenet N, Avril MF, Magnaldo T.

PLoS One. 2015 Dec 22;10(12):e0145369. doi: 10.1371/journal.pone.0145369. eCollection 2015.

7.

The patched/hedgehog/smoothened signalling pathway in human breast cancer: no evidence for H133Y SHH, PTCH and SMO mutations.

Vorechovský I, Benediktsson KP, Toftgård R.

Eur J Cancer. 1999 May;35(5):711-3.

PMID:
10505029
8.

A novel mutation of the PTCH1 gene activates the Shh/Gli signaling pathway in a Chinese family with nevoid basal cell carcinoma syndrome.

Zhang T, Chen M, Lü Y, Xing Q, Chen W.

Biochem Biophys Res Commun. 2011 Jun 3;409(2):166-70. doi: 10.1016/j.bbrc.2011.04.047. Epub 2011 Apr 13.

PMID:
21514272
9.

Elucidating the role of molecular signaling pathways in the tumorigenesis of basal cell carcinoma.

Tang JY.

Semin Cutan Med Surg. 2011 Dec;30(4 Suppl):S6-9. doi: 10.1016/j.sder.2011.11.001. Review.

PMID:
22177103
10.

Protein kinase A activation inhibits oncogenic Sonic hedgehog signalling and suppresses basal cell carcinoma of the skin.

Makinodan E, Marneros AG.

Exp Dermatol. 2012 Nov;21(11):847-52. doi: 10.1111/exd.12016.

PMID:
23163650
11.

Targeting the hedgehog pathway to treat basal cell carcinoma.

Geeraert P, Williams JS, Brownell I.

J Drugs Dermatol. 2013 May;12(5):519-23. Review.

PMID:
23652945
12.

Correlations between the Sonic Hedgehog pathway and basal cell carcinoma.

Lupi O.

Int J Dermatol. 2007 Nov;46(11):1113-7. Review.

PMID:
17988327
13.

Activation of the Sonic Hedgehog pathway in thyroid neoplasms and its potential role in tumor cell proliferation.

Xu X, Ding H, Rao G, Arora S, Saclarides CP, Esparaz J, Gattuso P, Solorzano CC, Prinz RA.

Endocr Relat Cancer. 2012 Apr 10;19(2):167-79. doi: 10.1530/ERC-11-0305. Print 2012 Apr.

14.

Relation between sonic hedgehog pathway gene polymorphisms and basal cell carcinoma development in the Polish population.

Lesiak A, Sobolewska-Sztychny D, Majak P, Sobjanek M, Wodz K, Sygut KP, Majsterek I, Wozniacka A, Narbutt J.

Arch Dermatol Res. 2016 Jan;308(1):39-47. doi: 10.1007/s00403-015-1612-9. Epub 2015 Nov 21.

PMID:
26590974
15.

Expression of sonic hedgehog signal transducers, patched and smoothened, in human basal cell carcinoma.

Tojo M, Mori T, Kiyosawa H, Honma Y, Tanno Y, Kanazawa KY, Yokoya S, Kaneko F, Wanaka A.

Pathol Int. 1999 Aug;49(8):687-94.

PMID:
10504535
16.

Hedgehog signaling is synergistically enhanced by nutritional deprivation and ligand stimulation in human fibroblasts of Gorlin syndrome.

Mizuochi H, Fujii K, Shiohama T, Uchikawa H, Shimojo N.

Biochem Biophys Res Commun. 2015 Feb 13;457(3):318-23. doi: 10.1016/j.bbrc.2014.12.108. Epub 2015 Jan 7.

PMID:
25576868
17.

Activating Smoothened mutations in sporadic basal-cell carcinoma.

Xie J, Murone M, Luoh SM, Ryan A, Gu Q, Zhang C, Bonifas JM, Lam CW, Hynes M, Goddard A, Rosenthal A, Epstein EH Jr, de Sauvage FJ.

Nature. 1998 Jan 1;391(6662):90-2.

PMID:
9422511
18.

A missense mutation in PTCH2 underlies dominantly inherited NBCCS in a Chinese family.

Fan Z, Li J, Du J, Zhang H, Shen Y, Wang CY, Wang S.

J Med Genet. 2008 May;45(5):303-8. doi: 10.1136/jmg.2007.055343. Epub 2008 Feb 19.

PMID:
18285427
19.

Hedgehog-signaling is upregulated in non-producing human adrenal adenomas and antagonism of hedgehog-signaling inhibits proliferation of NCI-H295R cells and an immortalized primary human adrenal cell line.

Werminghaus P, Haase M, Hornsby PJ, Schinner S, Schott M, Malendowicz LK, Lammers BJ, Goretzki PE, Müller-Mattheis V, Markus Giessing, Willenberg HS.

J Steroid Biochem Mol Biol. 2014 Jan;139:7-15. doi: 10.1016/j.jsbmb.2013.09.007. Epub 2013 Sep 21.

PMID:
24063979
20.

Basal cell carcinoma: pathophysiology.

Sehgal VN, Chatterjee K, Pandhi D, Khurana A.

Skinmed. 2014 May-Jun;12(3):176-81.

PMID:
25134314

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