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Items: 1 to 20 of 113

1.

Nobiletin suppresses the proliferation and induces apoptosis involving MAPKs and caspase-8/-9/-3 signals in human acute myeloid leukemia cells.

Hsiao PC, Lee WJ, Yang SF, Tan P, Chen HY, Lee LM, Chang JL, Lai GM, Chow JM, Chien MH.

Tumour Biol. 2014 Dec;35(12):11903-11. doi: 10.1007/s13277-014-2457-0. Epub 2014 Aug 28.

PMID:
25164609
2.

Nobiletin, a Polymethoxylated Flavone, Inhibits Glioma Cell Growth and Migration via Arresting Cell Cycle and Suppressing MAPK and Akt Pathways.

Lien LM, Wang MJ, Chen RJ, Chiu HC, Wu JL, Shen MY, Chou DS, Sheu JR, Lin KH, Lu WJ.

Phytother Res. 2016 Feb;30(2):214-21. doi: 10.1002/ptr.5517. Epub 2015 Nov 12.

PMID:
26560814
3.

Pterostilbene simultaneously induced G0/G1-phase arrest and MAPK-mediated mitochondrial-derived apoptosis in human acute myeloid leukemia cell lines.

Hsiao PC, Chou YE, Tan P, Lee WJ, Yang SF, Chow JM, Chen HY, Lin CH, Lee LM, Chien MH.

PLoS One. 2014 Aug 21;9(8):e105342. doi: 10.1371/journal.pone.0105342. eCollection 2014.

4.

Cantharidic acid induces apoptosis of human leukemic HL-60 cells via c-Jun N-terminal kinase-regulated caspase-8/-9/-3 activation pathway.

Wang SC, Chow JM, Chien MH, Lin CW, Chen HY, Hsiao PC, Yang SF.

Environ Toxicol. 2018 Apr;33(4):514-522. doi: 10.1002/tox.22537. Epub 2018 Jan 18.

PMID:
29345422
5.

Hispolon induces apoptosis through JNK1/2-mediated activation of a caspase-8, -9, and -3-dependent pathway in acute myeloid leukemia (AML) cells and inhibits AML xenograft tumor growth in vivo.

Hsiao PC, Hsieh YH, Chow JM, Yang SF, Hsiao M, Hua KT, Lin CH, Chen HY, Chien MH.

J Agric Food Chem. 2013 Oct 23;61(42):10063-73. doi: 10.1021/jf402956m. Epub 2013 Oct 15.

PMID:
24093560
6.

Glabridin mediate caspases activation and induces apoptosis through JNK1/2 and p38 MAPK pathway in human promyelocytic leukemia cells.

Huang HL, Hsieh MJ, Chien MH, Chen HY, Yang SF, Hsiao PC.

PLoS One. 2014 Jun 5;9(6):e98943. doi: 10.1371/journal.pone.0098943. eCollection 2014.

7.

Involvement of histone H3 phosphorylation through p38 MAPK pathway activation in casticin-induced cytocidal effects against the human promyelocytic cell line HL-60.

Kikuchi H, Yuan B, Yuhara E, Takagi N, Toyoda H.

Int J Oncol. 2013 Dec;43(6):2046-56. doi: 10.3892/ijo.2013.2106. Epub 2013 Sep 20.

PMID:
24064676
8.

Nobiletin induces apoptosis and potentiates the effects of the anticancer drug 5-fluorouracil in p53-mutated SNU-16 human gastric cancer cells.

Moon JY, Cho M, Ahn KS, Cho SK.

Nutr Cancer. 2013;65(2):286-95. doi: 10.1080/01635581.2013.756529.

PMID:
23441616
9.

Radotinib inhibits acute myeloid leukemia cell proliferation via induction of mitochondrial-dependent apoptosis and CDK inhibitors.

Heo SK, Noh EK, Gwon GD, Kim JY, Jo JC, Choi Y, Koh S, Baek JH, Min YJ, Kim H.

Eur J Pharmacol. 2016 Oct 15;789:280-290. doi: 10.1016/j.ejphar.2016.07.049. Epub 2016 Jul 28.

PMID:
27477352
11.

Antiproliferative and apoptosis-inducing activity of nobiletin against three subtypes of human breast cancer cell lines.

Chen C, Ono M, Takeshima M, Nakano S.

Anticancer Res. 2014 Apr;34(4):1785-92.

PMID:
24692711
12.
13.

The mechanism of acacetin-induced apoptosis on oral squamous cell carcinoma.

Kim CD, Cha JD, Li S, Cha IH.

Arch Oral Biol. 2015 Sep;60(9):1283-98. doi: 10.1016/j.archoralbio.2015.05.009. Epub 2015 Jun 8.

PMID:
26099663
15.

Anti-leukemic effect of 2-pyrone derivatives via MAPK and PI3 kinase pathways.

Yoon JS, Won YW, Kim SJ, Oh SJ, Kim ES, Kim BK, Cho CG, Choi JH, Park BB, Lee MH, Lee YY.

Invest New Drugs. 2012 Dec;30(6):2284-93. doi: 10.1007/s10637-012-9814-x. Epub 2012 Apr 19.

PMID:
22526834
16.

Tangeretin and nobiletin induce G1 cell cycle arrest but not apoptosis in human breast and colon cancer cells.

Morley KL, Ferguson PJ, Koropatnick J.

Cancer Lett. 2007 Jun 18;251(1):168-78. Epub 2007 Jan 2.

PMID:
17197076
17.

Sulforaphane-induced apoptosis in human leukemia HL-60 cells through extrinsic and intrinsic signal pathways and altering associated genes expression assayed by cDNA microarray.

Shang HS, Shih YL, Lee CH, Hsueh SC, Liu JY, Liao NC, Chen YL, Huang YP, Lu HF, Chung JG.

Environ Toxicol. 2017 Jan;32(1):311-328. doi: 10.1002/tox.22237. Epub 2016 Feb 2.

PMID:
26833863
18.

Icaritin induces AML cell apoptosis via the MAPK/ERK and PI3K/AKT signal pathways.

Li Q, Huai L, Zhang C, Wang C, Jia Y, Chen Y, Yu P, Wang H, Rao Q, Wang M, Wang J.

Int J Hematol. 2013 May;97(5):617-23. doi: 10.1007/s12185-013-1317-9. Epub 2013 Apr 3.

PMID:
23550021
19.

Dioscin suppresses human laryngeal cancer cells growth via induction of cell-cycle arrest and MAPK-mediated mitochondrial-derived apoptosis and inhibition of tumor invasion.

Si L, Zheng L, Xu L, Yin L, Han X, Qi Y, Xu Y, Wang C, Peng J.

Eur J Pharmacol. 2016 Mar 5;774:105-17. doi: 10.1016/j.ejphar.2016.02.009. Epub 2016 Feb 3.

PMID:
26849940
20.

Matrine induces apoptosis in human acute myeloid leukemia cells via the mitochondrial pathway and Akt inactivation.

Zhang S, Zhang Y, Zhuang Y, Wang J, Ye J, Zhang S, Wu J, Yu K, Han Y.

PLoS One. 2012;7(10):e46853. doi: 10.1371/journal.pone.0046853. Epub 2012 Oct 8.

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