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Items: 1 to 20 of 139

1.

Monitoring of dabigatran anticoagulation and its reversal in vitro by thrombelastography.

Solbeck S, Meyer MA, Johansson PI, Meyer AS, Cotton BA, Stensballe J, Schött U, Ostrowski SR.

Int J Cardiol. 2014 Oct 20;176(3):794-9. doi: 10.1016/j.ijcard.2014.07.084. Epub 2014 Aug 4.

PMID:
25156858
2.

Thrombin generation using the calibrated automated thrombinoscope to assess reversibility of dabigatran and rivaroxaban.

Herrmann R, Thom J, Wood A, Phillips M, Muhammad S, Baker R.

Thromb Haemost. 2014 May 5;111(5):989-95. doi: 10.1160/TH13-07-0607. Epub 2013 Dec 19.

PMID:
24352511
3.

Thrombelastography detects dabigatran at therapeutic concentrations in vitro to the same extent as gold-standard tests.

Solbeck S, Ostrowski SR, Stensballe J, Johansson PI.

Int J Cardiol. 2016 Apr 1;208:14-8. doi: 10.1016/j.ijcard.2016.01.148. Epub 2016 Jan 9.

PMID:
26826624
4.

Global coagulation tests: their applicability for measuring direct factor Xa- and thrombin inhibition and reversal of anticoagulation by prothrombin complex concentrate.

Dinkelaar J, Patiwael S, Harenberg J, Leyte A, Brinkman HJ.

Clin Chem Lab Med. 2014 Nov;52(11):1615-23. doi: 10.1515/cclm-2014-0307.

PMID:
24902009
6.

Dabigatran and its reversal with recombinant factor VIIa and prothrombin complex concentrate: a Sonoclot in vitro study.

Sølbeck S, Nilsson CU, Engström M, Ostrowski SR, Johansson PI.

Scand J Clin Lab Invest. 2014 Oct;74(7):591-8. doi: 10.3109/00365513.2014.921930. Epub 2014 Jun 9.

PMID:
24909158
7.

Reversal of dabigatran effects in models of thrombin generation and hemostasis by factor VIIa and prothrombin complex concentrate.

Hoffman M, Volovyk Z, Monroe DM.

Anesthesiology. 2015 Feb;122(2):353-62. doi: 10.1097/ALN.0000000000000540.

PMID:
25502064
8.

Use of Thromboelastography (TEG) for Detection of New Oral Anticoagulants.

Dias JD, Norem K, Doorneweerd DD, Thurer RL, Popovsky MA, Omert LA.

Arch Pathol Lab Med. 2015 May;139(5):665-73. doi: 10.5858/arpa.2014-0170-OA.

PMID:
25927150
9.

Performance of coagulation tests in patients on therapeutic doses of dabigatran: a cross-sectional pharmacodynamic study based on peak and trough plasma levels.

Hawes EM, Deal AM, Funk-Adcock D, Gosselin R, Jeanneret C, Cook AM, Taylor JM, Whinna HC, Winkler AM, Moll S.

J Thromb Haemost. 2013 Aug;11(8):1493-502. doi: 10.1111/jth.12308.

10.

In vitro studies using a global hemostasis assay to examine the anticoagulation effects in plasma by the direct thrombin inhibitors: dabigatran and argatroban.

He S, Wallèn H, Bark N, Blombäck M.

J Thromb Thrombolysis. 2013 Feb;35(2):131-9. doi: 10.1007/s11239-012-0791-x.

PMID:
22843196
11.

Management of major bleeding complications and emergency surgery in patients on long-term treatment with direct oral anticoagulants, thrombin or factor-Xa inhibitors: proposals of the working group on perioperative haemostasis (GIHP) - March 2013.

Pernod G, Albaladejo P, Godier A, Samama CM, Susen S, Gruel Y, Blais N, Fontana P, Cohen A, Llau JV, Rosencher N, Schved JF, de Maistre E, Samama MM, Mismetti P, Sié P; Working Group on Perioperative Haemostasis.

Arch Cardiovasc Dis. 2013 Jun-Jul;106(6-7):382-93. doi: 10.1016/j.acvd.2013.04.009. Epub 2013 Jun 25.

12.

The effect of dabigatran on the activated partial thromboplastin time and thrombin time as determined by the Hemoclot thrombin inhibitor assay in patient plasma samples.

Hapgood G, Butler J, Malan E, Chunilal S, Tran H.

Thromb Haemost. 2013 Aug;110(2):308-15. doi: 10.1160/TH13-04-0301. Epub 2013 Jun 20.

PMID:
23783268
13.

Reversal of rivaroxaban-induced anticoagulation with prothrombin complex concentrate, activated prothrombin complex concentrate and recombinant activated factor VII in vitro.

Perzborn E, Heitmeier S, Laux V, Buchmüller A.

Thromb Res. 2014 Apr;133(4):671-81. doi: 10.1016/j.thromres.2014.01.017. Epub 2014 Jan 21.

14.

Reversal of dabigatran anticoagulation by prothrombin complex concentrate (Beriplex P/N) in a rabbit model.

Pragst I, Zeitler SH, Doerr B, Kaspereit FJ, Herzog E, Dickneite G, van Ryn J.

J Thromb Haemost. 2012 Sep;10(9):1841-8. doi: 10.1111/j.1538-7836.2012.04859.x.

15.

Differential profiles of thrombin inhibitors (heparin, hirudin, bivalirudin, and dabigatran) in the thrombin generation assay and thromboelastography in vitro.

Xu Y, Wu W, Wang L, Chintala M, Plump AS, Ogletree ML, Chen Z.

Blood Coagul Fibrinolysis. 2013 Apr;24(3):332-8. doi: 10.1097/MBC.0b013e32835e4219.

PMID:
23348428
16.

Measurement of dabigatran in standardly used clinical assays, whole blood viscoelastic coagulation, and thrombin generation assays.

van Ryn J, Grottke O, Spronk H.

Clin Lab Med. 2014 Sep;34(3):479-501. doi: 10.1016/j.cll.2014.06.008. Epub 2014 Jul 22. Review.

PMID:
25168938
17.

Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects.

Eerenberg ES, Kamphuisen PW, Sijpkens MK, Meijers JC, Buller HR, Levi M.

Circulation. 2011 Oct 4;124(14):1573-9. doi: 10.1161/CIRCULATIONAHA.111.029017. Epub 2011 Sep 6.

18.

Dabigatran etexilate--a novel, reversible, oral direct thrombin inhibitor: interpretation of coagulation assays and reversal of anticoagulant activity.

van Ryn J, Stangier J, Haertter S, Liesenfeld KH, Wienen W, Feuring M, Clemens A.

Thromb Haemost. 2010 Jun;103(6):1116-27. doi: 10.1160/TH09-11-0758. Epub 2010 Mar 29. Review.

PMID:
20352166
19.

Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: a randomised crossover ex vivo study in healthy volunteers.

Marlu R, Hodaj E, Paris A, Albaladejo P, Cracowski JL, Pernod G.

Thromb Haemost. 2012 Aug;108(2):217-24. doi: 10.1160/TH12-03-0179. Epub 2012 May 25. Erratum in: Thromb Haemost. 2013 Jan;109(1):169.

PMID:
22627883
20.

γT -S195A thrombin reduces the anticoagulant effects of dabigatran in vitro and in vivo.

Sheffield WP, Lambourne MD, Eltringham-Smith LJ, Bhakta V, Arnold DM, Crowther MA.

J Thromb Haemost. 2014 Jul;12(7):1110-5. doi: 10.1111/jth.12601. Epub 2014 Jun 19.

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