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Items: 1 to 20 of 350

1.

Molecular basis for ebolavirus VP35 suppression of human dendritic cell maturation.

Yen B, Mulder LC, Martinez O, Basler CF.

J Virol. 2014 Nov;88(21):12500-10. doi: 10.1128/JVI.02163-14. Epub 2014 Aug 20.

2.

Effects of Filovirus Interferon Antagonists on Responses of Human Monocyte-Derived Dendritic Cells to RNA Virus Infection.

Yen BC, Basler CF.

J Virol. 2016 Apr 29;90(10):5108-5118. doi: 10.1128/JVI.00191-16. Print 2016 May 15.

3.

Ebolavirus VP35 suppresses IFN production from conventional but not plasmacytoid dendritic cells.

Leung LW, Park MS, Martinez O, Valmas C, López CB, Basler CF.

Immunol Cell Biol. 2011 Oct;89(7):792-802. doi: 10.1038/icb.2010.169. Epub 2011 Jan 25.

4.

Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling.

Cárdenas WB, Loo YM, Gale M Jr, Hartman AL, Kimberlin CR, Martínez-Sobrido L, Saphire EO, Basler CF.

J Virol. 2006 Jun;80(11):5168-78.

5.

Differential Regulation of Interferon Responses by Ebola and Marburg Virus VP35 Proteins.

Edwards MR, Liu G, Mire CE, Sureshchandra S, Luthra P, Yen B, Shabman RS, Leung DW, Messaoudi I, Geisbert TW, Amarasinghe GK, Basler CF.

Cell Rep. 2016 Feb 23;14(7):1632-1640. doi: 10.1016/j.celrep.2016.01.049. Epub 2016 Feb 11.

6.

Structural basis for Marburg virus VP35-mediated immune evasion mechanisms.

Ramanan P, Edwards MR, Shabman RS, Leung DW, Endlich-Frazier AC, Borek DM, Otwinowski Z, Liu G, Huh J, Basler CF, Amarasinghe GK.

Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):20661-6. doi: 10.1073/pnas.1213559109. Epub 2012 Nov 26.

7.

Mutual antagonism between the Ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome.

Luthra P, Ramanan P, Mire CE, Weisend C, Tsuda Y, Yen B, Liu G, Leung DW, Geisbert TW, Ebihara H, Amarasinghe GK, Basler CF.

Cell Host Microbe. 2013 Jul 17;14(1):74-84. doi: 10.1016/j.chom.2013.06.010.

8.

Different Temporal Effects of Ebola Virus VP35 and VP24 Proteins on Global Gene Expression in Human Dendritic Cells.

Ilinykh PA, Lubaki NM, Widen SG, Renn LA, Theisen TC, Rabin RL, Wood TG, Bukreyev A.

J Virol. 2015 Aug;89(15):7567-83. doi: 10.1128/JVI.00924-15. Epub 2015 May 13.

9.

The VP35 protein of Ebola virus impairs dendritic cell maturation induced by virus and lipopolysaccharide.

Jin H, Yan Z, Prabhakar BS, Feng Z, Ma Y, Verpooten D, Ganesh B, He B.

J Gen Virol. 2010 Feb;91(Pt 2):352-61. doi: 10.1099/vir.0.017343-0. Epub 2009 Oct 14.

10.

The Ebola virus VP35 protein binds viral immunostimulatory and host RNAs identified through deep sequencing.

Dilley KA, Voorhies AA, Luthra P, Puri V, Stockwell TB, Lorenzi H, Basler CF, Shabman RS.

PLoS One. 2017 Jun 21;12(6):e0178717. doi: 10.1371/journal.pone.0178717. eCollection 2017.

11.

Evasion of interferon responses by Ebola and Marburg viruses.

Basler CF, Amarasinghe GK.

J Interferon Cytokine Res. 2009 Sep;29(9):511-20. doi: 10.1089/jir.2009.0076. Review.

12.

Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35.

Leung DW, Prins KC, Borek DM, Farahbakhsh M, Tufariello JM, Ramanan P, Nix JC, Helgeson LA, Otwinowski Z, Honzatko RB, Basler CF, Amarasinghe GK.

Nat Struct Mol Biol. 2010 Feb;17(2):165-72. doi: 10.1038/nsmb.1765. Epub 2010 Jan 17.

13.

dsRNA binding characterization of full length recombinant wild type and mutants Zaire ebolavirus VP35.

Zinzula L, Esposito F, Pala D, Tramontano E.

Antiviral Res. 2012 Mar;93(3):354-63. doi: 10.1016/j.antiviral.2012.01.005. Epub 2012 Jan 25.

PMID:
22289166
14.

Mutations abrogating VP35 interaction with double-stranded RNA render Ebola virus avirulent in guinea pigs.

Prins KC, Delpeut S, Leung DW, Reynard O, Volchkova VA, Reid SP, Ramanan P, Cárdenas WB, Amarasinghe GK, Volchkov VE, Basler CF.

J Virol. 2010 Mar;84(6):3004-15. doi: 10.1128/JVI.02459-09. Epub 2010 Jan 13.

15.

RLR-mediated production of interferon-β by a human dendritic cell subset and its role in virus-specific immunity.

Szabo A, Bene K, Gogolák P, Réthi B, Lányi Á, Jankovich I, Dezső B, Rajnavölgyi E.

J Leukoc Biol. 2012 Jul;92(1):159-69. doi: 10.1189/jlb.0711360. Epub 2012 Apr 18.

PMID:
22517920
16.

Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1.

Prins KC, Cárdenas WB, Basler CF.

J Virol. 2009 Apr;83(7):3069-77. doi: 10.1128/JVI.01875-08. Epub 2009 Jan 19.

17.

Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery.

Chang TH, Kubota T, Matsuoka M, Jones S, Bradfute SB, Bray M, Ozato K.

PLoS Pathog. 2009 Jun;5(6):e1000493. doi: 10.1371/journal.ppat.1000493. Epub 2009 Jun 26.

18.

TLR3 and Rig-like receptor on myeloid dendritic cells and Rig-like receptor on human NK cells are both mandatory for production of IFN-gamma in response to double-stranded RNA.

Perrot I, Deauvieau F, Massacrier C, Hughes N, Garrone P, Durand I, Demaria O, Viaud N, Gauthier L, Blery M, Bonnefoy-Berard N, Morel Y, Tschopp J, Alexopoulou L, Trinchieri G, Paturel C, Caux C.

J Immunol. 2010 Aug 15;185(4):2080-8. doi: 10.4049/jimmunol.1000532. Epub 2010 Jul 16.

19.

West Nile Virus NS1 Antagonizes Interferon Beta Production by Targeting RIG-I and MDA5.

Zhang HL, Ye HQ, Liu SQ, Deng CL, Li XD, Shi PY, Zhang B.

J Virol. 2017 Aug 24;91(18). pii: e02396-16. doi: 10.1128/JVI.02396-16. Print 2017 Sep 15.

20.

Lloviu virus VP24 and VP35 proteins function as innate immune antagonists in human and bat cells.

Feagins AR, Basler CF.

Virology. 2015 Nov;485:145-52. doi: 10.1016/j.virol.2015.07.010. Epub 2015 Aug 6.

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